@aaconnor1 @BronskiJoseph The EDU3 refers to the polygenic score (PGS) for educational attainment. It's a metric for assessing the strength of people's genetic endowment for succeeding in education (which correlates quite strongly with IQ). Comes from 2018
@ExposingRaicsts @aaronm75172349 The study is behind a paywall. See photos. https://t.co/dbpfoMe3ST https://t.co/aq25a3fXQP
@nuance_guy @AporiaMagazine @_HelenDale We have identified 1,271 single-nucleotide polymorphisms (SNPs) that are significantly associated with educational attainment. We can use the alleles at those SNPs to estimate an individual's cognitive ability. http
@entoreklaw @FeverLyfe @pinkiep98052392 @sneako It was but the ncbi/nih link no longer works The other one still does https://t.co/LyC3S7kRJb
@VVVisuri @JaninaJunnola @hurumdara2 Yhteys näkyy myös geneettisellä tasolla: osittain samat geenit selittävät sekä koulutusta että kognitiivista kykyä: https://t.co/PjohPbWKgJ
@RHALWB @Aella_Girl Nonsense. There are many studies which use polygenic scores associated with educational attainment https://t.co/XbSW69I53r
@LaleiNk @EstoriaEspanna @Juan__RP @aaandrios Ya puestos también podemos retrotraernos a alguna ameba primordial del pasado: pero eso no elimina las diferencias entre subespecies humanas actuales. Y la cuestión es que existen diferencias genéticas notable
@thedukesofdank @nighttimemedia @ArchaeologyGame Intelligence has a heritability of 0.5-0.8. This isn't even debatable. https://t.co/w11HbtWIZn We use polygenic scores associated with educational attainment to predict outcomes. https://t.co/XbSW69I53r Y
@JacobKishnevi @ArchaeologyGame By using polygenic scores. https://t.co/XbSW69I53r
This means that the effect of a SNP will 'shrink' within-family when there is AM, even without IGEs or other confounding factors. Results for the amount of shrinkage as a function of the strength of AM have been given by several authors (@LoicYengo, (https
@jegrifff Its behind a paywall. https://t.co/dbpfoMe3ST
RT @cremieuxrecueil: @katey1776 @monitoringbias No, it isn't inherited more from the mother and sibling results still show greater male var…
RT @cremieuxrecueil: @katey1776 @monitoringbias No, it isn't inherited more from the mother and sibling results still show greater male var…
@katey1776 @monitoringbias No, it isn't inherited more from the mother and sibling results still show greater male variance: https://t.co/VT3Ss9qHev For a description of how variances differ with means: https://t.co/JUHgwgFN8a More links: https://t.co/
GWAS: educational attainment reflects thousands of SNPs that are mostly active in the brain. Polygenic scores "explain 11–13% of the variance in educational attainment and 7–10% of the variance in cognitive performance." Glia not involved. https://t.co
RT @cremieuxrecueil: @ProtoLSMutt The X-chromosome contributes as much as you'd expect for a chromosome of its size in terms of loci, and a…
The X-chromosome is not all that abnormal when it comes educational attainment. https://t.co/vXAC2gzIaD
RT @Alexis_Verger: ça reste 1 corrélation et non 1 causalité, c'est bien pour ça que les auteurs de cette étude par exemple utilisent le mo…
@zugzjuan96 https://t.co/Apqd018Jcb ahí dice que tiene un tamaño del efecto de 11-13%, comparable a haber nacido en una familia rica (15%)
@ProtoLSMutt The X-chromosome contributes as much as you'd expect for a chromosome of its size in terms of loci, and a little less than you'd expect in terms of megabases. https://t.co/vOXqffvRw9 https://t.co/EGRIDqpOMd
@kevinburch @craigcandor Perhaps enabling embryo selection for educational attainment? The predictive value is small, but small (assuming there are no side effects) is better than nothing. https://t.co/evCFxWl97w
@tadesouaiaia Could embryo selection increase the chances of having a smarter kid? Could the accuracy of this increase in the near future? https://t.co/evCFxWl97w
@sean_johnsen Here is the link to the paper https://t.co/qOO5xFx9tK
@sean_johnsen If you want to learn more about the methods, to validate your opinion, I suggest checking out this thread on the GWAS that identified the variants for educational attainment https://t.co/eLdVmmibR5
@KayteSB @peterubel Also, consider some of the sociogenomic studies if not already on your list, e.g., https://t.co/V5R38gOBo5
@charlesmurray The author of this essay, James Lee, was lead author on a very high impact paper in 2018 which showed certain DNA differences are linked to educational attainment and IQ. This study was led by a group called SSGAC. 1/ https://t.co/EegwK9DptR
@StevePittelli @AnrothanN @charlesmurray Please explain what you specifically believe is objectionable about this article and why you felt it was important for you to imply that Lee, being lead author on an article with dozens of collaborators, had some °
Given these background, when the first large scale well-powered GWAS of educational attainment came out, many were surprised to find no enrichment in glial cells. https://t.co/UWeHpRwIOI https://t.co/7BQLqm0yoa
@kot8a 在学年数に相関がみられる、のやつです https://t.co/2AyBcccfMg
And of course the paper cites the flagship of #GWASturbation studies the one that the Uvalde massacre's shooter has cited in his "manifesto", the "educational attainment" one https://t.co/1rClcjH6hu
@utikejt @stevcho91 @Bulkington__ Teze 1. Naslednost stečenog obrazovanja je visoka. 2. Za blagostanje jedne zemlje nije svejedno kakva je raspodela zanimanja njenog stanovništva. Deo izvora https://t.co/tT1J2z35So https://t.co/tSXc0lbavi https://t.co/Yn
@AnaYorke Žao mi je što Vas vređa kad neko piše istinu https://t.co/j00DGrmhDS https://t.co/AfmKYo3N0w
@KukurikuKokoda Pokrića mejnstrim nauke👇 https://t.co/j00DGrDkFS https://t.co/AfmKYnLDMo https://t.co/pcSIStuOU1
@Ana_neznana Sve je moguće, ali verovatnoće nisu iste. https://t.co/j00DGrmhDS https://t.co/noAx3PgYtu
If more people became influenced by 1517/Thiel Fellow dropout culture, it would satiate Pachter's desire to utterly destroy the James J. Lee GWAS educational attainment paper (https://t.co/4a5dT10q0C) by abolishing the strange correlation between educatio
To the UK Biobank @uk_biobank: You might be aware the study linked here was cited as part of a rationale by a mass shooter in Buffalo, NY. I see a UKBB application organization (11425), but a study number (12512) that does not appear to exist. /1 https:/
O link da pesquisa pra quem tiver curiosidade https://t.co/pvTs9nZVct
@RobertoIGOCARD1 @LeoKitsune https://t.co/8Mfu6dDyOT o artigo completo para você.
..."Se você não tem os recursos da família, até as crianças brilhantes – aquelas naturalmente dotadas – terão que enfrentar batalhas muito difíceis”, disse Thom. “Muito potencial está sendo desperdiçado" Leia mais em: https://t.co/lfu9ijO6X6 A pesquisa:
For example https://t.co/f5mnS8lWWy
@Blinde_owl @yajrumujlo Я не биолог, знаю то, что в популярных книжках (напри. The Genetic Lottery от Harden). Группа снипов определяют будущее образование и, вероятно, интеллект. Или, например, это https://t.co/pcKCXO566G
@NPirastu @renebekkers @HermanWerfhorst @dr_appie It’s in the EA3 GWAS (https://t.co/Sh2c04FKAG), the average rg between the cohorts is like ~.72.
RT @ewanbirney: @lpachter I think the strongest ones are the Iceland series (this is one https://t.co/qMYtZ10pq7) but of course the other i…
RT @ewanbirney: @lpachter I think the strongest ones are the Iceland series (this is one https://t.co/qMYtZ10pq7) but of course the other i…
@lpachter I think the strongest ones are the Iceland series (this is one https://t.co/qMYtZ10pq7) but of course the other is the big meta-analysis (https://t.co/j5idqfuMgm)
For comparison, the genome-wide signal from an 1.1 million GWAS of educational attainment (a highly polygenic trait) explain only <4% of the phenotypic variance (first bars) https://t.co/UWeHpRwIOI https://t.co/3udQ0s6EVB
As an outsider, it strikes me that the epigenetics research agenda poses a misspecification challenge to gene-economists as the latter zero out interaction effects (by ignoring the interplay between genes and environmental factors). https://t.co/UNKVrVeoc
RT @PGCgenetics: Reanalysis of CNVs across 11 published studies in ADHD showed enrichment of genes & networks across species. We identified…
RT @PGCgenetics: Reanalysis of CNVs across 11 published studies in ADHD showed enrichment of genes & networks across species. We identified…
@FDrenos
Reanalysis of CNVs across 11 published studies in ADHD showed enrichment of genes & networks across species. We identified novel candidate genes for ADHD through integration across species and variant types. https://t.co/15lScKOsRq
@jennymaria @jonasvlachos @KGJLagerkranser @PetterLundborg Den här är ju också viktig: https://t.co/C6jfFR6Wzm
@CurrieJamie @AaronL001 @GodlessCranium @AuthorConfusion @DavidePiffer what expert has found the genetic code for intelligence? The modern GWAS research for educational attainment (EA) have found more than 1000 genetic code differences for IQ/EA. Here is r
@tmwaring @KevinHong1991 yes, and as far as i understand, if one restricts themselves to EA GWAS, "good culture/education genes" might be primarily related to brain development, neural connection, the CNS... not sure how informative that really is at the e
@krichard1212 @tailcalled @SecretBaboon @ent3c Increased brain (cerebral cortex) size has been linked to increased IQ. Gene differences have been linked to educational attainment (EA3 polygenic score) and it has now been shown that many are genetically cor
Here's one such study: Gene discovery and polygenic prediction from a 1.1-million-person GWAS of educational attainment https://t.co/SlIwQqa4Ut https://t.co/JFIU0PESEq
Does IQ have an impact that compensates for all the other racist, classist, ablest, socio-economic shit? Not really. https://t.co/KbrvDgOB2q
@lg__Ek Ok, det här är komplicerat. Jag ska försöka att förenkla det. 1. I en storskalig studie som omfattade över 1 miljon deltagare har forskare identifierat ett tusental genvarianter som är associerade med högre utbildningslängd. Den artikeln finns hä
Y aquí hay mucho que debatir ya que los científicos tenemos claro que la inteligencia es un concepto muy complejo con características genéticas pero también ambientales… https://t.co/22xHpWaB77
@wil_da_beast630 Theory: https://t.co/nSmjlJqwU6 https://t.co/MDiAEVEB3E Empirical evidence: https://t.co/iRa5uhMGc9 Specific alleles (in progress): https://t.co/pB1IJA0VaW https://t.co/d3Eg47IiFG https://t.co/pESOmnQkik (note that finishing 3 is argua
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals https://t.co/jrBhTG6GjD
@Superutz @DieTwychologin @4therecords Klingt vor allem nach Neid auf diejenigen die halt mehr Glück hatten. Diese Studie hat auf Basis von Daten von 1,1 Mio Menschen genetische Marker für statisch deutlich signifikante Unterschiede in den kognitiven Fähig
@rubenarslan @laurencejmshowe So the method used to estimate h2 simply requires to large a sample (like 6k minimum) to estimate h2 per study, the one study that did as far as I know is Lee et al. the big Edu GWAS (https://t.co/Sh2c04FKAG) their supp table
First Behav Genetics Law: any trait is heritable. Educational attainment is discussed as an example: https://t.co/MZahuB58p6 Also an example of the "Fourth Law", that a typical trait is associated with many genetic variants, each explaining a small perce
@gregoryconnor11 @HumanVarieties @ResearchGate Lee et al.’s whole paper here is interesting, but just read their conclusion and the section on within-family sampling for what i’m talking about. https://t.co/csuKtLhHUg
@evo_homo @gcochran99 @TeaGeeGeePea @CovfefeAnon @arguablywrong @AryanCrash @ArchieN1966 @RhiannonDauster @EPoe187 "some of the predictive power of the polygenic score reflects environmental amplification of the genetic effects. Without controls for this b
@wil_da_beast630 @realchrisrufo ...by genetic factors summing additively - and 2) isn't contaminated by environmental influences (for example, "genetic nurture") and 3) is more-or-less equally predictive in the comparison groups. We're getting there. See
@monsoon0 Those genetic markers are FAR from a crystal ball... here's the GWAS paper where their markers came from: https://t.co/AsGN0xkxxw https://t.co/40AyGkxyof
Source 3: https://t.co/8CNndqqStH
RT @PGCgenetics: Reanalysis of CNVs across 11 published studies in ADHD showed enrichment of genes & networks across species. Novel candida…
Reanalysis of CNVs across 11 published studies in ADHD showed enrichment of genes & networks across species. Novel candidate genes for ADHD through integration across species and variant types. https://t.co/15lScL63IY
How come we never hear about this now well-established result from proponents of GWAS? Esp when they're writing these papers advocating for how some GWAS predict education so very well... That your scores are terrible for non-Whites seems like a rather fun
@jstevewhite @amiguello1 @Pseudobadger @SarahGrynpas @and_furiouser @karischoonbee @jessesingal No, GWAS identifies genes that have association with a particular phenotype. It is this collection of genes that is used in the paper (identified in Lee et al.
@BlackMa30578734 Une des études citées (la plus grosse en 2018 selon l'article) trouve que “les scores polygéniques expliquent 11-13% de la variance dans le succès scolaire et 7-10% de la variance dans les performance cognitives”. (Paye ton “hérédité bien
@ProvNero @DrunkenPanda42 @Systemrelevant0 Mal einige Quellen dazu: https://t.co/ipVuzduoK5 https://t.co/05FoVA883Z https://t.co/QXmI9Brmld Zum Teil wurden auch schon Zusammenhänge zu spezifischen Genen hergestellt (jedoch nur kleinere Anteile): https://t.
@veroyeet @TedJasper1 @NBCNews https://t.co/7wtaJmW0TD There are studies coming out now showing that Europeans are much more likely than Africans to possess certain genes that predict intelligence. It's why there's been such a push to ban this kind of rese
12/25 As a result, our new PGS contains information about income over and above that contained in the PGS for educational attainment from our previous study in N~1.1mio individuals (see Table 4 and tweet 10 in this thread)... https://t.co/i7zcqXnsYC
7/25 26 of our loci were previously found to be associated with average household income https://t.co/p1Kox4Y7qB and 31 with educational attainment https://t.co/i7zcqXnsYC. Thus, the genetic architectures of different measures of socioeconomic attainment a
@charlesmurray EA herit (Silv ea 2020) is crit bec GWAS (Lee ea 2018, Dunkel ea 2019, Piffer 2019/20) req large SS and more direct/stand tests of GI are not curr ava at scale https://t.co/oaBq1FRfuZ https://t.co/FB2yUBidkn https://t.co/8NQLBi6FlL https://
@marosse @Estadao @soracy Acabei de te dar a reportagem da BBC que cita dados da OCDE e PISA. O vídeo do Atila tem as referências em baixo de pesquisas acadêmicas. https://t.co/RRtkURWzvw https://t.co/GVQnsAqvCu https://t.co/FK4CEdSNy9
RT @RoyAFrye1: @DustinAventHolt @primalpoly @ent3c Some of the genomic DNA variation that influences IQ and educational attainment has been…
RT @RoyAFrye1: @DustinAventHolt @primalpoly @ent3c Some of the genomic DNA variation that influences IQ and educational attainment has been…
RT @RoyAFrye1: @DustinAventHolt @primalpoly @ent3c Some of the genomic DNA variation that influences IQ and educational attainment has been…
RT @RoyAFrye1: @DustinAventHolt @primalpoly @ent3c Some of the genomic DNA variation that influences IQ and educational attainment has been…
RT @RoyAFrye1: @DustinAventHolt @primalpoly @ent3c Some of the genomic DNA variation that influences IQ and educational attainment has been…
@Thinking__T @Bioliberalism @symmo1969 @a_centrism @Parapraxis1980 @patrickamon @sapinker @Quillette sorry link for JJ Lee et al. was not correct, try this link https://t.co/EegwK9CREj