RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @ElementoLab: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https:/…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @StuartJRitchie: For some reason I genuinely can’t fathom, polygenic scores have a lot of haters. This thread (and paper) should convinc…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
Nice first steps! True personalized approaches implies a framework shift from reductionism to complexity. From genetic scores to multidimensional complex phenotypes #SystemsMedicine #ThinkSystemic
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https://t.co/GQOMOx9tSo
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @eyemiyake: 引用RT>多因子疾患のゲノムについてはこういう使い方でしょうね。 我々は眼科疾患について研究しています。例えば、片眼の加齢黄斑変性において、反対眼にも同疾患が発症するリスクは、遺伝的リスクスコア上位10%では10年で51%であったのに対し、下位1…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT GustaveRoussy "RT FAndreMD: polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versus mammogram GustaveRoussy GroupeUNICANCER https://t.co/74gelmadDp"
引用RT>多因子疾患のゲノムについてはこういう使い方でしょうね。 我々は眼科疾患について研究しています。例えば、片眼の加齢黄斑変性において、反対眼にも同疾患が発症するリスクは、遺伝的リスクスコア上位10%では10年で51%であったのに対し、下位10%では3%でした。 https://t.co/foqhALJ4Bg
RT @FAndreMD: polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versu…
RT @FAndreMD: polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versu…
The original letter should be read by all interested in the use of genomics for disease prevention
polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versus mammogram @GustaveRoussy @GroupeUNICANCER
Impressive predictive power of polygenic risk score for coronary artery disease (and others). Top 8% of individuals three times as likely to have the disease. #Genomics #PrecisionMedicine #CAD https://t.co/d9Zh5pxXip https://t.co/gkuykRgI9B
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations | Nature Genetics https://t.co/hWhzUSa87m
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
#gamechanger translating GWAS into a clinically useful tool - kudos @skathire and team
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @StuartJRitchie: For some reason I genuinely can’t fathom, polygenic scores have a lot of haters. This thread (and paper) should convinc…
RT @whsource: "Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations". 8% of th…
We are all complex! Finally it is acknowledged. Now translation into therapy and care for patients is warranted........, which might be a long way to go - but we now have the direction!
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @HoulstonLab_ICR: Development & validation of genome-wide polygenic #risk scores in five common diseases @skathire @amitvkhera @NatureGe…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @_jdevos_: Important paper. Has the time come to include polygenic risk prediction in clinical care? This does indeed raise the question…
冠動脈疾患(CAD)を含む5疾患において、約660万の変異データからGenome-wide Polygenic Score (GPS)を算出した研究。 CADでは、GPS上位8%のその他92%と比較したオッズ比が3.0。これはMonogenic FHののオッズ比に近い。 GPS上位8%はFHと同様の予防・治療が必要かもしれない。 https://t.co/HwM1tXiUf8
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
Take control of your health - learn your risk score & take action! #genomics
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @danweiner92: Exciting papers in @NatureGenet today, especially development+validation+clinical musings re genetic risk scores by @skath…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @whsource: "Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations". 8% of th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @jyasuda1: 先のRTは心房細動や心血管疾患、糖尿病のような代表的な疾患についてpolygenicなアプローチによってリスク三倍のヒトを同定できるようにした、というNature Geneticsの論文のようだ。今週のNGはそうした記事が複数載っているようだ。関係者…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
This should be a bit of a dampener on the idea that we will all be getting precision Rx for all disease any time soon....
先のRTは心房細動や心血管疾患、糖尿病のような代表的な疾患についてpolygenicなアプローチによってリスク三倍のヒトを同定できるようにした、というNature Geneticsの論文のようだ。今週のNGはそうした記事が複数載っているようだ。関係者は必見と見た。 https://t.co/3kA82MRryG
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @whsource: "Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations". 8% of th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
Important study.
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @drdargaray: Un nuevo ensayo genético que detecta la susceptibilidad individual para un ataque cardiaco. Cual será el papel del cribado…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @danweiner92: Exciting papers in @NatureGenet today, especially development+validation+clinical musings re genetic risk scores by @skath…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @StuartJRitchie: For some reason I genuinely can’t fathom, polygenic scores have a lot of haters. This thread (and paper) should convinc…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @StuartJRitchie: For some reason I genuinely can’t fathom, polygenic scores have a lot of haters. This thread (and paper) should convinc…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
Un nuevo ensayo genético que detecta la susceptibilidad individual para un ataque cardiaco. Cual será el papel del cribado genético de predisposición al infarto en un futuro (no lejano..)?
I hope an equally talented team can come up with a polygenic score for chronic #kidney disease too! What do you think, @kidneyomicsamps @kirylukk? #genomics