Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. https://t.co/ERBXkBqjny
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @BiotechRadar: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https:/…
#gwas - detect if you have 3x - 8x higher risk of common diseases, thanks to new risk scores https://t.co/3POHzUpbbT
RT @brent_p: also, AUC for 74 variants at genomewide significance for CAD was 0.791 and AUC for 6.63 million variants (imputed from ~800K)…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @brent_p: also, AUC for 74 variants at genomewide significance for CAD was 0.791 and AUC for 6.63 million variants (imputed from ~800K)…
RT @brent_p: also, AUC for 74 variants at genomewide significance for CAD was 0.791 and AUC for 6.63 million variants (imputed from ~800K)…
RT @RonZimmernPHG: The original letter should be read by all interested in the use of genomics for disease prevention https://t.co/CjnFSYl0…
also, AUC for 74 variants at genomewide significance for CAD was 0.791 and AUC for 6.63 million variants (imputed from ~800K) was only improved to 0.806 -- though the OR per SD was more improved. (From Supp Table 1)
“Kathiresan can calculate risk scores .... simply by reanalyzing the kind of raw data people receive after sending a cheek swab to companies like 23andMe.” raw data = full of errors (false positives and false negatives).
How does this relate to your work, @AtheroLab?
RT @clopezcorrea: Great article in the use of #genomics for #orevention of common diseases https://t.co/CutXzpGQKf
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @DrJCheungEP: Brilliant work by @skathire @steven_lubitz et al on polygenic risk scores. A lot of attention on CAD in the press but of c…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @chrisricupero: “Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations” from…
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
“Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations” from @skathire
RT @venkmurthy: @ewanbirney @skathire Media-ites, perhaps also talk to @cecilejanssens or @f2harrell about the deep flaws in this line of t…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @DrJCheungEP: Brilliant work by @skathire @steven_lubitz et al on polygenic risk scores. A lot of attention on CAD in the press but of c…
RT @FAndreMD: polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versu…
RT @skathire: Thx @DrJCheungEP I agree A fib polygenic score result even more intriguing as: A fib heritable essentially *no* large ef…
Thx @DrJCheungEP I agree A fib polygenic score result even more intriguing as: A fib heritable essentially *no* large effect monogenic component for this disease but for top ~1% polygenic score, greater than 5-fold higher risk
Brilliant work by @skathire @steven_lubitz et al on polygenic risk scores. A lot of attention on CAD in the press but of course I'm intrigued by the AF story. How will risk score predict response to therapies like AF ablation? https://t.co/xq2erXIL9X https
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @timspector: There may still be hope that genes can help predict risk of common diseases - though a fair way to go still - even identica…
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
@ewanbirney @skathire Media-ites, perhaps also talk to @cecilejanssens or @f2harrell about the deep flaws in this line of thinking and the limitations rather than just blindly #hyping. https://t.co/41pnYrOb2w
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @lcpilling: Nice paper and thread on CVD polygenic risk by @skathire: genetic risk is non-linear, i.e. those at the top have substantial…
RT @FAndreMD: polygenic risk score of breast cancer is currently being evaluated in a randomized trial testing personalized screening versu…
RT @RonZimmernPHG: The original letter should be read by all interested in the use of genomics for disease prevention https://t.co/CjnFSYl0…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @ruifeitas: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https://t…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @ElementoLab: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https:/…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @RonZimmernPHG: The original letter should be read by all interested in the use of genomics for disease prevention https://t.co/CjnFSYl0…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations | Nature Genetics https://t.co/P1xwHLip96 #genomics #PolygenicPredictor #DiseaseRisk https://t.co/AXUYq0G3li
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
La bella ciencia de la cardiología cada vez más cerca de buscar los responsables del infarto y esta cada vez más lejos.
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @lcpilling: Nice paper and thread on CVD polygenic risk by @skathire: genetic risk is non-linear, i.e. those at the top have substantial…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @drdargaray: Un nuevo ensayo genético que detecta la susceptibilidad individual para un ataque cardiaco. Cual será el papel del cribado…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
CAD等典型的な五つの多遺伝子病の #ゲノムワイド多遺伝子スコア を提示。CADではリスク閾値の3倍以上の8.0%集団を特定できる: MGH。 https://t.co/u1xwSw8peF
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @RonZimmernPHG: The original letter should be read by all interested in the use of genomics for disease prevention https://t.co/CjnFSYl0…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…