RT @NatureGenet: #NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.c…
RT @markmccarthyoxf: Excellent - and to my mind fair - summary of the potential of grs for patient care, and the obstacles that need to be…
RT @NatureGenet: #NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.c…
RT @markmccarthyoxf: Excellent - and to my mind fair - summary of the potential of grs for patient care, and the obstacles that need to be…
RT @NatureGenet: #NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.c…
RT @NatureGenet: #NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.c…
RT @markmccarthyoxf: Excellent - and to my mind fair - summary of the potential of grs for patient care, and the obstacles that need to be…
Excellent - and to my mind fair - summary of the potential of grs for patient care, and the obstacles that need to be overcome to make it a reality....
RT @NatureGenet: #NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.c…
The Schork family weighs in on the use of polygenic risk scores in clinical practice! Not sure that requiring evidence of clinical utility is part of “outdated ways of thinking about health maintenance.” Via @NatureGenet https://t.co/nhYEVw6Unx
#NatGenNV Genetic risks and clinical rewards (Schork, Schork & Schork) https://t.co/Yu2j4ED6hZ on Khera et al. https://t.co/Roi4vMiZhV https://t.co/LmMLCiS7Rd
RT @amitvkhera: Fantastic explainer of our recent work on polygenic risk scores and implications from @rplenge Open-access paper at: http…
RT @amitvkhera: Fantastic explainer of our recent work on polygenic risk scores and implications from @rplenge Open-access paper at: http…
RT @amitvkhera: Fantastic explainer of our recent work on polygenic risk scores and implications from @rplenge Open-access paper at: http…
Fantastic explainer of our recent work on polygenic risk scores and implications from @rplenge Open-access paper at: https://t.co/nRrfTVepty
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @henning_lars: Good tweetorial about https://t.co/NNhc8WaCYF https://t.co/gMwG5WW8Kx
Good tweetorial about https://t.co/NNhc8WaCYF
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
Clear, balanced, comprehensive. Wonderful job contrasting recent @NatureGenet article on polygenic risk scores in CAD with similar article a month before on PRS in educational status. Great weekend read. https://t.co/xf3YV9NDE3 https://t.co/Ld6gaNyqze 2
@crowthrm @S_brimble @lastwalsh Moving towards the future of genetic risk prediction and stratification. Important when treatment associated with therapeutic burden, and for patient enrichment in trials
RT @C_Glastonbury: Yes: "it is time to contemplate the inclusion of polygenic risk prediction in clinical care" https://t.co/anJzK0p5a2 ..…
RT @C_Glastonbury: Yes: "it is time to contemplate the inclusion of polygenic risk prediction in clinical care" https://t.co/anJzK0p5a2 ..…
RT @C_Glastonbury: Yes: "it is time to contemplate the inclusion of polygenic risk prediction in clinical care" https://t.co/anJzK0p5a2 ..…
Yes: "it is time to contemplate the inclusion of polygenic risk prediction in clinical care" https://t.co/anJzK0p5a2 ... For middle aged affluent Caucasian Europeans...
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
RT @EricTopol: @FridaGhitis @CircAHA the polygenic risk score for heart disease described here https://t.co/eRisYjpUtB and here https://t.c…
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @broadinstitute: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https://t.co/HwnKQoq7aE via @NatureGenet
We agree. It is also time to explore strategies to accelerate their rapid adoption and sustained use in appropriate clinical and public health settings. #ImplementationScience #ImplementationResearch #HLBSpopOMICS @NIH_NHLBI https://t.co/Aj3xfmJ4o6
@FridaGhitis @CircAHA the polygenic risk score for heart disease described here https://t.co/eRisYjpUtB and here https://t.co/scex6RcN2r perfect to help people decide about taking statins
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
This paper claims that genome-wide #polygenic scores can help in #RiskStratification similar to mendelian diseases. https://t.co/yFsQiXbeQf
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
Use polygenic genetic markers as predictors of risk, prognosis and treatment improvements for common diseases. Move towards Personalized Medicine with your Health Map 👣📥📋👩🏽⚕️👨🏻⚕️ https://t.co/bRPxAtSxMM
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @MuinJKhoury: Genetic risk scores are back in the limelight. The approach can identify 1.5% to 8.0% of the population at greater than th…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @Genomeducator: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations https://t.co/IKwxyfjf7Y
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
It is time to contemplate the inclusion of polygenic risk prediction in clinical care, and discuss relevant issues. https://t.co/rVZC0QWuwO
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
Polygenic Risk Score = #PM101: Genomics enables one to exploit the genetics of populations and individuals to predict disease risk, a component of P4 Medicine: Predictive, Preventive, Personalized, and Participatory. @ISBLeeHood
RT @broadinstitute: .@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet…
.@amitvkhera explains how polygenic risk scores are developed. You can read Khera's recent publication in @NatureGenet here https://t.co/Kvq9i7UzGw and read the Broad news story here https://t.co/0stxr3Q1QM https://t.co/AKdDk3AT3j
Cada vez queda menos para tener en cuenta los riesgos poligénicos en la práctica clínica https://t.co/ltkNZYpiyI https://t.co/ltkNZYpiyI
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
Great work by @skathire and colleagues on polygenic risk & scoring in common human disease, thoughts on translation into clinical practice. https://t.co/OVlREuTnlJ
RT @brent_p: also, AUC for 74 variants at genomewide significance for CAD was 0.791 and AUC for 6.63 million variants (imputed from ~800K)…
#Genome-wide polygenic scores for common diseases identify individuals with #risk #equivalent to monogenic mutation..https://t.co/RH1n3fmtr2
@GCBrianne @elo81 @chicagogenetics @skathire @JennaGuLCGC @katie_stoll Found this thread helpful: https://t.co/7PQbvWjbfB
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
@Alex_Peluffo @skathire Thanks Alex! FYI, open access version of article at: https://t.co/nRrfTVepty
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations: https://t.co/lwbUl4Qnrg https://t.co/6TKaOPk2iq
RT @skathire: What is inherited basis for heart attack? A new quantitative (genome-wide polygenic score) that captures inherited liability…
RT @cecilejanssens: My take home message from the latest polygenic risk paper: 6.6 million snps improve AUC by 0.015. In the derivation sam…
RT @broadinstitute: What is a polygenic risk score? How is it calculated? Watch @skathire explain –in this video. Read his group's latest p…
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. https://t.co/sX7r9EWBc0
A research team reports a new kind of genome analysis that could identify large fractions of the population who have a much higher risk of developing serious common diseases, including coronary artery disease, breast cancer, or type 2 diabetes. https://t.
Researchers predict risk for common deadly diseases from millions of genetic variants A research team reports a new kind of genome analysis that could identify large fractions of the population who have a much higher risk of... https://t.co/6P4inwo7F6
RT @EricTopol: Important assessment of polygenic risk scores for 5 common diseases @NatureGenet by @amitvkhera @skathire @broadinstitute @M…
RT @victor_faundes: La medicina de precisión cada vez más cerca de la práctica clínica habitual. Sin embargo, urge replicar estos estudios…
RT @wintonARK: Current state of the art: have a single unlucky mutation and you have a 4x higher risk of heart attack, so targeted statins…
RT @Chri_Pristipino: Nice first steps! True personalized approaches implies a framework shift from reductionism to complexity. From geneti…
1/ “Because allele frequencies, linkage disequilibrium patterns, and effect sizes of common polymorphisms vary with ancestry, the specific GPS here will not have optimal predictive power for other (non European) ethnic groups.” https://t.co/BumiJbqsV6
RT @NatureGenet: Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (Khera e…
@RoxanaDaneshjou @epigencare @AdeAdamson The variants do not have to be causative (as long as they predict risks) as recent paper in Nature Genetics demonstrates for 5 common diseases https://t.co/zAsBJKGRCh