RT @ichiipsy: 「老化すると戻らない」という通説は、最近の研究を見てるともう当てはまらないと感じる。脳内の炎症を抑えて認知機能の低下を防いで回復させたり、視力を元に戻したりと「一度失ったものでも元に戻せる」という新しい目を見張るような研究結果が出てきてる。科学ってす…
RT @ichiipsy: 「老化すると戻らない」という通説は、最近の研究を見てるともう当てはまらないと感じる。脳内の炎症を抑えて認知機能の低下を防いで回復させたり、視力を元に戻したりと「一度失ったものでも元に戻せる」という新しい目を見張るような研究結果が出てきてる。科学ってす…
「老化すると戻らない」という通説は、最近の研究を見てるともう当てはまらないと感じる。脳内の炎症を抑えて認知機能の低下を防いで回復させたり、視力を元に戻したりと「一度失ったものでも元に戻せる」という新しい目を見張るような研究結果が出てきてる。科学ってすごい https://t.co/1yHIxUAf2v
RT @GoldLabCharite: Reduced cellular metabolism in the periheral immune system drives cognitive decline and chronic inflammation. Elegant s…
RT @nature: Cognitive decline can be reversed in mice by treating them with a drug that reduces inflammation and boosts the metabolism of i…
RT @DrMicroglia: Restoring metabolism of myeloid cells reverses cognitive decline in ageing. (2021) https://t.co/mICraynv0N
Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/Kyl7naRwI8
Ep !!! Això es força interesant. Vol dir que podría ser un camí per tirar enrere les malfuncions del cervell per l’envelliment. https://t.co/t4p0hz0KyE
@giollabhui
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @andvoge: Keep your macrophages and their metabolism fit! Very impressive work hot off the press @nature https://t.co/4XI4XABUCo
RT @andvoge: Keep your macrophages and their metabolism fit! Very impressive work hot off the press @nature https://t.co/4XI4XABUCo
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Myeloid metabolic reprogramming prevents cognitive aging 🤓
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/foNFKgX7xx
In ageing mice myeloid cell bioenergetics are suppressed in response to increased signalling by the lipid messenger prostaglandin E2 (PGE2), a major modulator of inflammation https://t.co/OEU6InQaZU
RT @nature: Cognitive decline can be reversed in mice by treating them with a drug that reduces inflammation and boosts the metabolism of i…
RT @aginghighlights: Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/nBND8jECKR https://t.co/zd5Ko1…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @GoldLabCharite: Reduced cellular metabolism in the periheral immune system drives cognitive decline and chronic inflammation. Elegant s…
Reduced cellular metabolism in the periheral immune system drives cognitive decline and chronic inflammation. Elegant study by @parasmin et al. in @nature with relevance for #immunometabolic depression https://t.co/kuL6U9MF0g https://t.co/U2xAzPpt8Q
RT @hugospiers: Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/1akSjPYZA2
RT @hugospiers: Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/1akSjPYZA2
"myeloid cell bioenergetics are suppressed in response to increased signalling by prostaglandin E2 (PGE2)" Minhas, P.S., et al. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature (2021). https://t.co/DfYt2ukrbe
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
"blockade of peripheral myeloid EP2 signalling is sufficient to restore cognition in aged mice" https://t.co/X3DkX5BfM1
RT @slavov_n: In ageing macrophages and microglia, PGE2 signalling promotes the sequestration of glucose into glycogen and reduces glucose…
Wow! Interesting findings! Really cool! Hope to figure out half of what they did!
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
This is awesome Mel! @dr_ohsopretty
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Layman's thoughts on recent-ish bio animal research into aging: seem like life longevity may be related to insulin/glucose (+ indirect inflammation) processing; may inversely be correlated w/ neural activity. - https://t.co/BJtrOT2Bol - https://t.co/C28d
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/9S7UsZGId8
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Reversing age-related cognitive decline via manipulation of myeloid cells in mice: https://t.co/Mz57mbYsR0
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
@DrPujaMehta1 @gpollara @LucyCKBell Oooor, PGE2 receptor antagonists? https://t.co/lm5SxJCiLi
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/unpRJMUmWY
RT @AgingBiology: Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/cgGAzluBfv
RT @CampbellNeuros1: Stunning paper from the journal Nature showing that age related decline in brain function can be suppressed by alterin…
RT @CampbellNeuros1: Stunning paper from the journal Nature showing that age related decline in brain function can be suppressed by alterin…
Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/MUZzcX66WX
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/Pgbw0pU9NE
RT @KrishRoyLab: Wow! Amazing! The #immunesystem strikes again. To me every known disorder/pathology is likely caused by immune dysfunction…
RT @AxL_Montagne: Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/TwlGkVuoKe
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
"Our study suggests that cognitive ageing is not a static or irrevocable condition but can be reversed by reprogramming myeloid glucose metabolism to restore youthful immune functions." https://t.co/pgYHNrmL3C
Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/yu1L7U26SO
RT @AxL_Montagne: Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/TwlGkVuoKe
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/TwlGkVuoKe
@dr_ohsopretty dropping another one of her gems🤩🥳
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @CampbellNeuros1: Stunning paper from the journal Nature showing that age related decline in brain function can be suppressed by alterin…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @AgingBiology: Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/cgGAzluBfv
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Neuroinflammation mechanisms of aging neurodegeneration, the PGE2 signalling pathway in macrophages and microglia. (Abstract. 20 Jan2021.)
RT @mkaeberlein: Impressive and important work. Yet more evidence that functional declines of aging are often reversible. Can't help but…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @KrishRoyLab: Wow! Amazing! The #immunesystem strikes again. To me every known disorder/pathology is likely caused by immune dysfunction…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
#liveforever! Beautiful @nature from @dr_ohsopretty @parasmin &co: #PGE2 via #EP2 dampens #metabolism of #phagocytes #microglia in #elder & #agedmice causing #succinate ⬆️ #inflammation cognitive impair! +pharmacological protection! https://t
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Very nice congrats!
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @KrishRoyLab: Wow! Amazing! The #immunesystem strikes again. To me every known disorder/pathology is likely caused by immune dysfunction…
Prostaglandin E2 suppresses macrophage and microglia bioenergetics, augmenting inflammation in aged mice. #inflammation #aging #metabolism @StanfordMed https://t.co/pHx2jqpqoD
Restoring metabolism of myeloid cells reverses cognitive decline in ageing https://t.co/DravFZgEXq
Wow! Amazing! The #immunesystem strikes again. To me every known disorder/pathology is likely caused by immune dysfunction or could be treated by restoring immune homeostasis, from Covid, to Cancer to now 👇 age related cognitive loss. #immunoengineering ht
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Stunning paper from the journal Nature showing that age related decline in brain function can be suppressed by altering metabolism of myeloid cells. $TSOI https://t.co/HsVcKiaMLl
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Restoring metabolism of myeloid cells reverses cognitive decline in ageing | Nature https://t.co/1akSjPYZA2
RT @FitzFitzsimons: inhibition of prostaglandin E2 receptor signalling rejuvenates cells, brain inflammation, hippocampal plasticity and me…
Prostaglandin E2 reduces glucose flux and mitochondrial respiration in ageing macrophages and microglia, and promotes cognitive decline. Cox2 inhibitor NSAIDs might rejuvenate cognitive ageing https://t.co/m7HZFbXhDU
RT @DrSTANtheMAN: Restoring #metabolism of myeloid cells reverses cognitive decline in #ageing | Nature #macrophages #microglia https://t…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
Very cool!!
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…
RT @dr_ohsopretty: Will go down in history as one of my most memorable postdoctoral discoveries and contributions. It was pure joy collabor…