RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats

Overview of attention for article published in Nature Neuroscience, July 2019

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RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats.

JRNLclub, 27 May 2020

Nat Neurosci. 2019 Sep;22(9):1383-1388. Yamada SB1,2, Gendron TF3, Niccoli T4,5,6, Genuth NR1,2,7, Grosely R8, Shi Y9, Glaria…

Gene essential to “hallmark” of ALS, identified

Scope Blog, 29 Jul 2019

There's a collection of neurodegenerative diseases that share a similar tell: protein-dense blobs that amass in the brain. They'r…