Spatially coordinated heterochromatinization of long synaptic genes in fragile X syndrome
Cell,
Megabase-scale H3K9me3 domains are connected by inter-chromosomal interactions, harboring long synaptic genes prone to…
Megabase-scale H3K9me3 domains are connected by inter-chromosomal interactions, harboring long synaptic genes prone to…
Genomics workflows typically map reads onto a reference genome as the foundation for downstream analyses. However, this poses…
TScan-II is a genome-scale platform that integrates endogenous antigen processing and T cell signaling, facilitating multiplex…
A designer tRNA neochromosome containing all 275 nuclear tRNA genes of Saccharomyces cerevisiae reveals unexpected genomic…
mRNA transcription in budding yeast increases with cell size due to the equilibrium kinetics of dosage-limiting RNA polymerase…
Subunits of SWI/SNF chromatin remodeling complexes are often mutated in disease, but it has been difficult to predict gene…
Generation of a comprehensive human transcription factor (TF) barcoded ORF library and further application to embryonic stem…
nature.com - Determining the effect of DNA methylation on chromatin structure and function in higher organisms is challenging…
In the 1930s the pseudonym Nicolas Bourbaki was adopted by a group of French mathematicians who sought to axiomatize and…
Recent losses in honey bee colonies are unusual in their severity, geographical distribution, and, in some cases, failure to…
The winners of BioMed Central’s 4th Annual Research Awards were announced at London’s Swiss Re Tower last week. The event was…
Cloud computing is becoming an increasingly popular phenomenon in the world of computing. Analysing data in ‘the cloud…
The short read aligner Bowtie has gone legitimate, with a publication last month in Genome Biology and a mention by GT’s Daily…
As already mentioned in my first blog, an increasing number of means now exist for putting out messages to selected (and…