A Chemically Controlled Cas9 Switch Enables Temporal Modulation of Diverse Effectors
Science in Seattle,
CRISPR-Cas9 has yielded a plethora of effectors, including targeted transcriptional activators, base editors and prime editors.
CRISPR-Cas9 has yielded a plethora of effectors, including targeted transcriptional activators, base editors and prime editors.
Innovative and fast-moving genome editing tools, such as base and prime editing, are showing how ingenious thinking can bypass…
A genomic revolution is poised to cure sickle cell and other genetic diseases -- Read more on ScientificAmerican.com
Researchers treated sickle cell disease in mice by directly editing the defective hemoglobin gene that causes the disease.
A team led by researchers at the Broad Institute and St. Jude Children’s Research Hospital has now demonstrated that a base…