BRCA1とRNA干渉経路が交絡するという刺激的な論文。BRCA1とDicer、AgoなどのRNAi関連分子が複合体を形成し、DNA-RNAハイブリッド+単鎖DNAで構成されるR-ループとDNA損傷関連短鎖RNA(sdRNA)の合成に関与し、PALB2–RAD52複合体によるDNA修復を促進している。Nature誌。https://t.co/dNHj0tlS3J
RT @weldeiry: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 | Nature https://t.co/ax0qNCivlc
RT @weldeiry: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 | Nature https://t.co/ax0qNCivlc
RT @weldeiry: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 | Nature https://t.co/ax0qNCivlc
BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 | Nature https://t.co/ax0qNCivlc
RT @luzzi_s: #EESGenomeInstability What a terrific talk by Elodie Hatchi on BRCA1-mediated DNA damage repair though a new class of short RN…
#EESGenomeInstability What a terrific talk by Elodie Hatchi on BRCA1-mediated DNA damage repair though a new class of short RNAs at transcription termination pause sites! Related paper here: https://t.co/3kJoyjXwF4
So unbelievably proud of the brilliant @LianaGoehring for her work in discovering a new use for a gene frequently mutated in #breastcancer
RT @LianaGoehring: I'm so excited to finally share our work uncovering a new role for BRCA1 in small-RNA driven repair! I've learned so muc…
I'm so excited to finally share our work uncovering a new role for BRCA1 in small-RNA driven repair! I've learned so much from this project and this team @DanaFarber https://t.co/sJyrB0xuWi
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @A_Abakir: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/9yZVPxNu4k
Can't keep up! A tremendous study uncovering yet more of the RNA world in DNA repair. https://t.co/50vtOzB2BO
RT @A_Abakir: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/9yZVPxNu4k
RT @A_Abakir: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/9yZVPxNu4k
RT @A_Abakir: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/9yZVPxNu4k
BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/9yZVPxNu4k
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
RT @CaronPierre13: BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52. https://t.co/6uYCXxvmde
BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 https://t.co/ubFslgdIo2