RT @duxpacis: Je te mets la référence de cette affirmation: https://t.co/N8zl0ppQSb
@Ari_Arifu2 Todos ignorantes menos tú? Y los que comulguen con tús teorías? 😆 Siendo médico en españa dudo hayas estudiado mucho. Más bien repetir y obedecer. A recetar antibióticos, también cuando no toca. Y a negar la ciencia en nombre de un dogma pich
RT @Locuste_: Puisque l'on trouve un RBD sur chaque protéine Spike, il y en a donc trois par spicule. Déployés simultanément, ils permett…
Puisque l'on trouve un RBD sur chaque protéine Spike, il y en a donc trois par spicule. Déployés simultanément, ils permettent ainsi la liaison d'une spicule avec trois récepteurs ACE2 en même temps. https://t.co/hmH5B1rXyX https://t.co/1FLaGtgHKE
Est ce celle ci @DIVIZIO1
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion | Nature https://t.co/Qver9KyoI8
Références Sur la Spike en général : https://t.co/44UsGKDwpX Changement de conformation de la Spike : https://t.co/N8zl0ppQSb
Je te mets la référence de cette affirmation: https://t.co/N8zl0ppQSb
@Christi22732005 @sarkasmus_sa1 @MathiasPriebe Dafür, dass es angeblich keine Tierversuche gab, findet man erstaunlich viele publizierte Studien über solche Tierversuche. https://t.co/OqZfiu8UCO https://t.co/aTABfGwlYy https://t.co/CgazFt9QPi
RT @carpe_diem0820: SARS-CoV-2 が感染する際の受容体結合と膜融合のためのスパイク蛋白質のプライミングの詳細 Receptor binding and priming of the spike protein of SARS-CoV-2 for m…
或いは、このnature論文で示された closed→open 構造変化の説明とも重なる。 標的細胞と膜融合をもたらし易くする構造変化をするというもの。 これを起こすのが荒瀬研のいう「感染増強抗体」なのだ。 (ただし抗体のFab単量体で結合してもダメ?っぽくて、図みたいな結合様式が必要らしい)
今までずっと「furin切断部位がS1とS2間にある」と思っていたが、実は少々違ってたみたいwスマン 正確には、S2内にあるっぽい。それを称して S2' と呼ぶ。 "S2 proximal to the secondary (S2′) cleavage site" 解離したS1は "S1-ACE2 dissociated monomer" >https://t.co/USl9vRxQHo
@noritren @FabrizioChiodo @RobiVil @giorgiogilestro @massimosandal Ma per i non addetti ai lavori, la forma fusa compare solo surante il binding con ACE2? (che poi sono quele domande da 1ML di $) (Immagine da https://t.co/wZHJAimbWU) https://t.co/R46q3toOg
I think of spike like a missile. We've seen a few optimizations: D614G: increased RBD p(Open), less S1 shedding -> more reliable homing beacon increased RBD affinity (multiple non-synonymous substitutions): increased accuracy of homing beacon https://
CryoEM!!(去年9月のNature) すごいんだけど、流行りの分野・手法にありがちな「クライオEMで撮れば、一般誌」みたいな感もあって、あまり好きじゃないの。 いや、すごいんだけどね。
https://t.co/wzs8WK2RKh -- We already understand so much; and based on what's there it may almost be easy to find out what exactly the mutations in the #B117 variant are changing; with some carefully set up molecular dynamics simulations. Who is doing that
RT @otavio_ranzani: Hoje saiu um estudo na @nature também usando CRYO-EM para mostrar o mecanismo de acoplamento da Proteína S e o receptor…
Nature ハイライト:SARS-CoV-2のスパイクは膜融合のための準備を行う | Nature | Nature Research: https://t.co/HqhfdGNGiL
RT @NatureJapan: Nature ハイライト:SARS-CoV-2のスパイクは膜融合のための準備を行う | Nature https://t.co/YEszdH6IQI #コロナウイルス #SARSCoV2
RT @NatureJapan: Nature ハイライト:SARS-CoV-2のスパイクは膜融合のための準備を行う | Nature https://t.co/YEszdH6IQI #コロナウイルス #SARSCoV2
Nature ハイライト:SARS-CoV-2のスパイクは膜融合のための準備を行う | Nature https://t.co/YEszdH6IQI #コロナウイルス #SARSCoV2
네이처 하이라이트:막 융합에 필요한 SARS-CoV-2 스파이크(Spike) 단백질의 수용체 결합과 프라이밍(Priming) https://t.co/JxYNazN0sN
Nature https://t.co/F4xrbVTIND
#カガク。#医。#生体分子。#感染。新型コロナウイルス(SARS-CoV-2|COVID-19)。Nature ハイライト「コロナウイルス:SARS-CoV-2のスパイクは膜融合のための準備を行う」 https://t.co/namQKTfCzk スパイク糖タンパク質。ACE2。論文は9/17刊。PDB 7A91~7A98(他データも引用)。
Sars News https://t.co/f1kIHCIRei
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion | Nature https://t.co/0eFto0DsSH
Sars 2 https://t.co/f1kIHCIRei
...the study of early-stage SARS-CoV-2 #infection of cells. Article by @donaldbenton, @wrobel_antoni, Pengqi Xu, Chloë Roustan, Stephen Martin, Peter Rosenthal, John Skehel & Steven Gamblin from @TheCrick & Sun Yat-sen University. Paper: https://
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
RT @ConquerCovid_19: A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in…
A study in @nature found the spike protein on #SARSCoV2 #coronavirus can adopt at least ten structural states when in contact with the human virus receptor ACE2. #SARSCoV2 infection begins when a spike protein binds with ACE2 cell surface receptors. https
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @FOHMaster: Am I the only one who finds this analysis extremely disturbing as it relates to #SARSCoV2 vaccine development? cc:@drbeen_m…
Sars-CoV-2 https://t.co/f1kIHCIRei
RT @FOHMaster: Am I the only one who finds this analysis extremely disturbing as it relates to #SARSCoV2 vaccine development? cc:@drbeen_m…
The ru$h to win the Covid19 vaccine development is do disturbing. This article ramps it up another notch.
RT @FOHMaster: Am I the only one who finds this analysis extremely disturbing as it relates to #SARSCoV2 vaccine development? cc:@drbeen_m…
Am I the only one who finds this analysis extremely disturbing as it relates to #SARSCoV2 vaccine development? cc:@drbeen_medical https://t.co/shBVW1T5b2 https://t.co/PiVPOF2dPW
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
Sars 2 News https://t.co/f1kIHCIRei
Original research - @nature 🔥💯 https://t.co/3mCqfJvkxB
Benton, D.J., Wrobel, A.G., Xu, P. et al. Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion. Nature (2020). https://t.co/iadhsHhQnt https://t.co/iadhsHhQnt
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
RT @M_Publichealth: Receptor binding and priming of the spike #protein of #SARSCoV2 for membrane fusion https://t.co/S4o2R592FM #MedicReS…
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural rearrangements between the cl…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural rearrangements between the cl…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural basis of S2 unsheathing by AC…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural rearrangements between the cl…
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
Laitetaan huonounisille vielä vähän luettavaa.
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
RT @DelthiaRicks: Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor o…
Scientists uncover the structural mechanism involved in how the #coronavirus binds -- latches onto -- the ACE2 receptor of human cells to cause infection. It's not a single step but a series of minuscule conformational changes https://t.co/6BZ7ca5tZw https
#ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural basis of S2 unsheathing by ACE2 binding | Steven Gamblin @TheCrick https://t.co/02xp03fgv9 https://t.co/ZZ785cx1q9
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural rearrangements between the cl…
#ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Structural rearrangements between the closed and ACE2-bound | Steven Gamblin @TheCrick https://t.co/02xp03fgv9 https://t.co/9Jy31OIo8B
RT @GaetanBurgio: Really interesting #COVID19 paper on the sequential steps of #SARSCoV2 Spike bind to ACE2 receptor investigated using Cry…
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
RT @mmw_lmw: #ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steve…
#ReceptorBinding and #Priming of the spike protein of #SARSCoV2 for #MembraneFusion | Sequential steps in ACE2 binding | Steven Gamblin @TheCrick https://t.co/02xp03fgv9 https://t.co/FoFSJ4LuB3
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
RT @GaetanBurgio: Really interesting #COVID19 paper on the sequential steps of #SARSCoV2 Spike bind to ACE2 receptor investigated using Cry…
Scientists uncover the structural mechanism of coronavirus receptor binding https://t.co/K6AsxX6Oeo https://t.co/Gnty3AER5K https://t.co/qf8zKEfaRR
RT @manuelacasasoli: Uncovering the structural states of the SARS-CoV-2 spike protein, the coronavirus receptor binding. #Science #pandem…
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion https://t.co/pbhw4WTLj3
RT @EricTopol: Just out @nature is the structural biology elucidation of the obligatory membrane fusion by which #SARSCoV2 gets into cells…
#SARSCoV2 infection requires the fusion of virus and cell membranes to release the virus genome into the cell 🦠 Read about how this fusion occurs, from @nature https://t.co/1PgNplMnM5
RT @GaetanBurgio: Really interesting #COVID19 paper on the sequential steps of #SARSCoV2 Spike bind to ACE2 receptor investigated using Cry…
New data published in @nature revealing the series of conformational changes during the structural binding mechanism of #SARS-Cov-2 spike #protein and #human #virus #receptor #ACE2. https://t.co/Kw5DzC7EFW
RT @nature: A paper in Nature provides a detailed view, by cryoEM, of how binding of ACE2 by the SARS-CoV-2 spike leads to the conformation…
Really interesting #COVID19 paper on the sequential steps of #SARSCoV2 Spike bind to ACE2 receptor investigated using CryoEM => close conformation, trimers formation, fusion with ACE2, RBD opening -> open conformation -> Monomer https://t.co/OVg6
N/ Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion. https://t.co/A7yjPmDROy
RT @EricTopol: Just out @nature is the structural biology elucidation of the obligatory membrane fusion by which #SARSCoV2 gets into cells…