Core idea is w. 150bp paired end seq, you can see whether a read is MNase-protected by nucleosome, by CTCF only, or by CTCF with cohesin - the data are consistent with the structure from Li 2020 (https://t.co/I1nHaMlHP7) showing cohesin at CTCF N-term http
RT @ID30_MASSIF1: New pub @ID30_MASSIF1 in @nature from @dpanne1 @embl and @LeicStructBio The structural basis for cohesin–CTCF-anchored lo…
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
Nature "The structural basis for cohesin–CTCF-anchored loops" https://t.co/ZJz4ZPcyBc https://t.co/116LXzRNBD cohesin の CES 領域に、今回結晶構造を解いている CTCF をはじめ、いろいろな蛋白質(由来のペプチド)が結合することを示している。他のペプチドとの構造も解いてほしい
NEW #LMBpublications The structural basis for cohesin-CTCF-anchored loops.https://t.co/PY28UVbDwo
I'll discuss recent work published here https://t.co/96cpUnKnwJ and here https://t.co/s5Sv93fott
RT @CTCF_Papers: The structural basis for cohesin-CTCF-anchored loops. https://t.co/RXmuxsjIq8
RT @chromatingroup: The transcription factor CTCF anchors chromatin loops via cohesin interaction. Yan Li and colleagues in @dpanne1 group…
RT @dpanne1: Fascinating how the interaction between a couple amino acids of CTCF and cohesin determine how our DNA is folded. Published in…
RT @RTB_HRoss: Biochemical Design: High-resolution crystal structure mapping reveals additional designs & functions in the cohesin-CTCF int…
RT @RTB_HRoss: Biochemical Design: High-resolution crystal structure mapping reveals additional designs & functions in the cohesin-CTCF int…
Biochemical Design: High-resolution crystal structure mapping reveals additional designs & functions in the cohesin-CTCF interaction that helps regulate chromatin folding. https://t.co/8J0DKTqbc0
Nice work
Fascinating how the interaction between a couple amino acids of CTCF and cohesin determine how our DNA is folded. Published in @nature read the paper here: https://t.co/eIP9FAopf0 @embl @esrfsynchrotron @LeicStructBio https://t.co/QHLryDbGjY
RT @chromatingroup: The transcription factor CTCF anchors chromatin loops via cohesin interaction. Yan Li and colleagues in @dpanne1 group…
The transcription factor CTCF anchors chromatin loops via cohesin interaction. Yan Li and colleagues in @dpanne1 group have solved the crystal structure of the SA2–SCC1 cohesins in a complex with small portion of the N-terminus of CTCF ….a thread 1/11 htt
네이처 하이라이트:코헤신-CTCF 연결 루프의 구조 https://t.co/8LdMPsKswG
Read my latest #research on CTCF-cohesin, published in @nature Read here: https://t.co/eIP9FAopf0
RT @pedrosaurio: Cancel everything, CTCF is not an octupus but rather a snake ... https://t.co/T3LGUOamar Beautiful! https://t.co/RsqORmz…
RT @pedrosaurio: Cancel everything, CTCF is not an octupus but rather a snake ... https://t.co/T3LGUOamar Beautiful! https://t.co/RsqORmz…
RT @pedrosaurio: Cancel everything, CTCF is not an octupus but rather a snake ... https://t.co/T3LGUOamar Beautiful! https://t.co/RsqORmz…
RT @pedrosaurio: Cancel everything, CTCF is not an octupus but rather a snake ... https://t.co/T3LGUOamar Beautiful! https://t.co/RsqORmz…
RT @pedrosaurio: Cancel everything, CTCF is not an octupus but rather a snake ... https://t.co/T3LGUOamar Beautiful! https://t.co/RsqORmz…
RT @deWitLab: The final version of our cohesin-CTCF structure/looping paper has been posted online. You can read it here: https://t.co/ZGSc…
The final version of our cohesin-CTCF structure/looping paper has been posted online. You can read it here: https://t.co/ZGScnJixiq
RT @dpanne1: Read my latest #research on CTCF-cohesin, published in @nature ) Read here: https://t.co/eIP9FAopf0
Read my latest #research on CTCF-cohesin, published in @nature ) Read here: https://t.co/eIP9FAopf0
The structural basis for cohesin–CTCF-anchored loops https://t.co/LZJYek4yif
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
@ElphegeNoraLab Does this figure S1 from https://t.co/I1nHaM3yAZ not clearly show direct CTCF-cohesin (well, Rad21-STAG2 cohesin interface) interaction? https://t.co/EZuem0vIf1
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
RT @generegulation: CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https:/…
CTCF mediates chromatin looping via N-terminal domain-dependent cohesin retention (new work by Pugacheva et al) https://t.co/EXm2FbMkFw. Also, see recent works by Li et al.: https://t.co/A5DC2EO49g; Nora et al.: https://t.co/hqeMw2RerD and Nishana et al.:
🔬 The structural basis for cohesin-CTCF-anchored loops. 📝 Nature. 👨🏻🔬 Li Y, et al. 🌎 https://t.co/UCh9WCz0O8 #science #research https://t.co/8O0u85KfIk
🔬 The structural basis for cohesin-CTCF-anchored loops. 📝 Nature. 👨🏻🔬 Li Y, et al. 🌎 https://t.co/UCh9WCz0O8 #science #research https://t.co/0xscUgSUXG
🔬 The structural basis for cohesin-CTCF-anchored loops. 📝 Nature. 👨🏻🔬 Li Y, et al. 🌎 https://t.co/UCh9WCz0O8 #science #research https://t.co/GOZukmnl8C
RT @oligopain: This thread describes some super exciting results about 'how' mammalian genomes are structured by loop extrusion. The 'why'…
🔬 The structural basis for cohesin-CTCF-anchored loops. 📝 Nature. 👨🏻🔬 Li Y, et al. 🌎 https://t.co/UCh9WCz0O8 #science #research https://t.co/waJ3KNr9gY
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
The structural basis for cohesin–CTCF-anchored loops | Nature https://t.co/cq92jEcNBA
RT @Anders_S_Hansen: 1/n Really important new paper identifying 2 amino acids in CTCF that interact with cohesin (SA2-Rad21 interface): htt…
RT @oligopain: This thread describes some super exciting results about 'how' mammalian genomes are structured by loop extrusion. The 'why'…
RT @oligopain: This thread describes some super exciting results about 'how' mammalian genomes are structured by loop extrusion. The 'why'…
RT @Anders_S_Hansen: 1/n Really important new paper identifying 2 amino acids in CTCF that interact with cohesin (SA2-Rad21 interface): htt…
This thread describes some super exciting results about 'how' mammalian genomes are structured by loop extrusion. The 'why' question remains open (imo) and more interesting than ever!
RT @ElphegeNoraLab: Fascinating discovery! CTCF does not merely block cohesin translocation, but also seem to protect it from unloading by…
RT @UrnovFyodor: Fellow intranuclear people - I encourage you to look at extended data fig 7a (effect on transcription) and the first para…
Fellow intranuclear people - I encourage you to look at extended data fig 7a (effect on transcription) and the first para on page 3. So much for us understanding what CTCF does, despite 1,910 papers about it. Also yay editing as tool to do definitive expts
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
RT @dpanne1: Our paper 'The structural basis for cohesin–CTCF-anchored loops' is now online: https://t.co/96cpUnsMFb
🔬 The structural basis for cohesin-CTCF-anchored loops. 📝 Nature. 👨🏻🔬 Li Y, et al. 🌎 https://t.co/UCh9WCz0O8 #science #research https://t.co/A1JsBc5Q4v
Trending on PubMed: The structural basis for cohesin-CTCF-anchored loops. https://t.co/exbyJCypg2
RT @Marjonvanruiten: Happy to share our recent work on the interaction between cohesin and CTCF. Fantastic collaboration with the group of…
RT @ElphegeNoraLab: Fascinating discovery! CTCF does not merely block cohesin translocation, but also seem to protect it from unloading by…
RT @GenomicsGurus: The structural basis for cohesin–CTCF-anchored loops https://t.co/3CBD1cjpEE
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
The structural basis for cohesin–CTCF-anchored loops https://t.co/3CBD1cjpEE
The structural basis for cohesin-CTCF-anchored loops. https://t.co/RXmuxsjIq8
The structural basis for cohesin-CTCF-anchored loops. https://t.co/GFKdsklHti
RT @Anders_S_Hansen: 1/n Really important new paper identifying 2 amino acids in CTCF that interact with cohesin (SA2-Rad21 interface): htt…
RT @LeicStructBio: wow, @dpanne1 's and colleagues' work on The structural basis for cohesin–CTCF-anchored loops https://t.co/7nsd2AkV7z in…
NEW #LMBpublications The structural basis for cohesin-CTCF-anchored loops.https://t.co/PY28UVbDwo
RT @ElphegeNoraLab: Fascinating discovery! CTCF does not merely block cohesin translocation, but also seem to protect it from unloading by…
RT @ID30_MASSIF1: New pub @ID30_MASSIF1 in @nature from @dpanne1 @embl and @LeicStructBio The structural basis for cohesin–CTCF-anchored lo…
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
RT @moncourvoisier: Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fu…
RT @ID30_MASSIF1: New pub @ID30_MASSIF1 in @nature from @dpanne1 @embl and @LeicStructBio The structural basis for cohesin–CTCF-anchored lo…
Another fantastic structure from @ID30_MASSIF1 data. @dpanne1 @embl (now @LeicStructBio) was an early uptake user of fully automated MX - he works with incredibly challenging systems = screening 1000s of 💎to get low res structures - thanks for having faith