RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
@EricTopol See also this paper from June 2019, with a 6h TAT, 96.6% sensitivity and 41.7% specificity (up to 100%/100% "after confirmatory quantitative PCR and pathobiont-specific gene analyses"). Sequencing accuracy & yield has improved substantially
RT @ae_mather: Foods have their own DNA that makes sequencing the bacteria present difficult. We combined/optimised methods by https://t.co…
Foods have their own DNA that makes sequencing the bacteria present difficult. We combined/optimised methods by https://t.co/sQo8DxOFAh and https://t.co/GokBtrQXPl to deplete the host (food) DNA. The % of prokaryotic reads ↑↑ by an average of 13x, up to 90
A9 - (8/11) This is already possible (in the research context) using nanopore sequencing. Here is @Justin_OGrady et al. showing the feasibility of identifying respiratory pathogens in ~ 6 hours using metagenomics. #ATSchat https://t.co/7DtdHvshd1
RT @TMC_online_: • Charalampous ve ark. Nature’da yayınlanan çalışmalarında alt solunum yolu enfeksiyonu şüpheli 40 hastada metagenomik sap…
RT @TMC_online_: • Charalampous ve ark. Nature’da yayınlanan çalışmalarında alt solunum yolu enfeksiyonu şüpheli 40 hastada metagenomik sap…
• Charalampous ve ark. Nature’da yayınlanan çalışmalarında alt solunum yolu enfeksiyonu şüpheli 40 hastada metagenomik saptamanın bakteriyel ve viral patojenler için oldukça duyarlı olduğunu gösterdi. https://t.co/dkEFBmUaGV @Justin_OGrady @NatureBiotech
@edschenck @Leopoldo_Segal @benjaminwumd Knowing the burden and diversity of bacteria in patient's respiratory tract might really clarify who is infected, who is colonized, and who's got non-pathogenic respiratory microbiota. Not unthinkable using existing
The depletion method that I followed was: @Justin_OGrady https://t.co/Xh6s3sYJWw
@hoellenmotte @NanoporeConf Hi. I wrote all the comments to the questions in my speaker chat. Please have a look there. Basically I followed Justin Ogrady's protocol for human DNA depletion: https://t.co/Xh6s3sYJWw
RT @sanchak74: I am probably not being able to evoke the same sense of disbelief I feel that this has not been done in 3 months. "Our opti…
RT @sanchak74: I am probably not being able to evoke the same sense of disbelief I feel that this has not been done in 3 months. "Our opti…
I am probably not being able to evoke the same sense of disbelief I feel that this has not been done in 3 months. "Our optimized method (6 h from sample to result) was 96.6% sensitive and 41.7% specific for pathogen detection compared with culture" https
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @pathogenomenick: @JoJofoth @winstanley_c @aaron_weimann @samstudio8 @Scalene and Laura Wright learnt @Justin_OGrady's saponin depletion…
@JoJofoth @winstanley_c @aaron_weimann @samstudio8 @Scalene and Laura Wright learnt @Justin_OGrady's saponin depletion method as published in NBT recently: https://t.co/WU48Kp5oxL - gives excellent enrichment and reveals lower abundance members of the comm
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @mira_ale: Secuenciación masiva del ADN con la técnica de nanoporos, para detectar patógenos respiratorios. Se plantea como alternativa…
RT @mira_ale: Secuenciación masiva del ADN con la técnica de nanoporos, para detectar patógenos respiratorios. Se plantea como alternativa…
RT @mira_ale: Secuenciación masiva del ADN con la técnica de nanoporos, para detectar patógenos respiratorios. Se plantea como alternativa…
RT @mira_ale: Secuenciación masiva del ADN con la técnica de nanoporos, para detectar patógenos respiratorios. Se plantea como alternativa…
Secuenciación masiva del ADN con la técnica de nanoporos, para detectar patógenos respiratorios. Se plantea como alternativa rápida al cultivo y con el añadido de identificar a la vez resistencias a antibióticos
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
@LabCflores @thedvke
RT @niklasjlang: @nanopore technologies definitetly have the potential to revolutionize #clinical #diagnostics! - combining #metagenomics a…
@nanopore technologies definitetly have the potential to revolutionize #clinical #diagnostics! - combining #metagenomics and nanopore enables diagnosis of lung infections via sputum in < 6 hrs with very high sensitivity! https://t.co/mZYGDRmB02 @Nature
@Justin_OGrady @medrxivpreprint @Pitt_CMM great team work on this one @PACCM @Pitt_CMM. Justin's protocol clearly works! https://t.co/4aft5MeHxx
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @LaskerFDN: Scientists at @TheQuadram and @uniofeastanglia developed a nanopore metagenomic sequencing method that more rapidly and accu…
Scientists at @TheQuadram and @uniofeastanglia developed a nanopore metagenomic sequencing method that more rapidly and accurately characterizes bacterial lower respiratory infections compared to the current gold standard clinical diagnosis. https://t.co/P
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @aroob_alhumaidy: This day’s Article: https://t.co/ILGGihd9Vt #MolecularInBrief #Nanopore #AMR
RT @aroob_alhumaidy: This day’s Article: https://t.co/ILGGihd9Vt #MolecularInBrief #Nanopore #AMR
This day’s Article: https://t.co/ILGGihd9Vt #MolecularInBrief #Nanopore #AMR
RT @Justin_OGrady: Interested in a Postdoc implementing this clinical metagenomics method in hospitals in collaboration with a diagnostics…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection The researchers developed a metagenomics method for bacterial LRI diagnosis that features efficient saponin-based host DNA depletion and nanopore sequencing. ht
cc @susheelbusi @LauradeNies
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection | Nature Biotechnology https://t.co/1EVDjW9gyU
Nice result to aim for NGS in diagnostics
Nanppore-based diagnostics of respiratory infections https://t.co/1TqgCbtuRf
Diagnosis of respiratory infections using nanopore metagenomic sequencing in 6 hours @NatureBiotech https://t.co/k2j1Vhl1Du
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
This is important because a delayed diagnosis can mean a mild infection has run rampant by the time you know what it is and what to use to treat it.
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
RT @EricTopol: Rapid @nanopore metagenomics: sequencing to make the microbial diagnosis of lung infection via sputum in < 6 hrs with very h…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
This might change the ICU health care practices. https://t.co/tGpmAkeUqw
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @nresearchnews: In @NatureBiotech, researchers present a metagenomics protocol that achieves untargeted diagnosis of bacterial lower res…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection | Nature Biotechnology https://t.co/k9zPg0Pkpj
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. https://t.co/e7JeOFj30E
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
#nanopore #metagenomic #sequencing for infectious disease #MedLab https://t.co/Agn9WuwY9t
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/DlA8LXNz2G
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. https://t.co/QBNMmwlM4x via @circleboom
RT @NanoporePapers: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. https://t.co/dqzzLqbOc…
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. https://t.co/0pKYus6ubF
Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection. https://t.co/dqzzLqbOc2 #NatBiotechnol
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
RT @Justin_OGrady: In case anyone is interested- I wrote a 'Behind the paper' blog post on the Nature Research Bioengineering community abo…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @NatureBiotech: Nanopore metagenomics enables rapid clinical diagnosis of bacterial lower respiratory infection https://t.co/3422Qdzd6B…
RT @Justin_OGrady: Interested in a Postdoc implementing this clinical metagenomics method in hospitals in collaboration with a diagnostics…
RT @Justin_OGrady: Delighted to share our paper on the diagnosis of respiratory tract infection using @nanopore metagenomics published toda…
Metagenomics used in diagnosis of respiratory tract infection!
RT @Justin_OGrady: In case anyone is interested- I wrote a 'Behind the paper' blog post on the Nature Research Bioengineering community abo…