The first five years of the collaboration yielded many successes including new E3 ligase recruiters for targeted protein degradation: https://t.co/ySlNlGslAg https://t.co/O1sPb5KfTY https://t.co/AwX2boTfFE https://t.co/SR9vRldCzH https://t.co/fy6HWM6yOw h
@DanNomura @UCB_Chemistry @j_sprads @genentech Congrats Dr. Jessica Spradlin @j_sprads! You did some amazing work as a graduate student in @DanNomura's lab! Like this beautiful research in @nchembio. :) https://t.co/3cLoBDzkpZ
去年出たNat. Chem. Biol. の文献はこれ https://t.co/BaGmBoC1vX
RT @PhytoceuticalsI: #Plant #terpenoids #research and #applications is a hot topic for the @PhytoceuticalsI International. Here is a great…
RT @CBioscien: Harnessing the anti-cancer natural product for targeted protein degradation #cancer #CBioscien #biology #oncology https://t…
Harnessing the anti-cancer natural product for targeted protein degradation #cancer #CBioscien #biology #oncology https://t.co/dS0p088sOY https://t.co/nWIziVklOM
抗がん剤として機能する天然物のNimbolideがE3ユビキチンリガーゼの1つであるRNF114のリガンドとして機能するらしく、それを利用したたんぱく質誘導分解 https://t.co/wpciGXN0cm
#Plant #terpenoids #research and #applications is a hot topic for the @PhytoceuticalsI International. Here is a great #information about a unique #druggable #modalities accessed by #natural #products for #cancer #therapy: https://t.co/9gpBb4LgJS https://t
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @jaybradner: Intriguing implications for #drugdiscovery – the study found that nimbolide can be used to recruit RNF114 for targeted pro…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @jaybradner: Intriguing implications for #drugdiscovery – the study found that nimbolide can be used to recruit RNF114 for targeted pro…
RT @jaybradner: Intriguing implications for #drugdiscovery – the study found that nimbolide can be used to recruit RNF114 for targeted pro…
Intriguing implications for #drugdiscovery – the study found that nimbolide can be used to recruit RNF114 for targeted protein degradation – and that synthetic small molecules that act on RNF114 the same way could do the same. #chembio
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @theresaoei: Nice use of activity based protein profiling to identify the mechanism of nimbolide’s inhibition of an E3 ligase. PLUS deve…
Nice use of activity based protein profiling to identify the mechanism of nimbolide’s inhibition of an E3 ligase. PLUS development for targeted protein degradation!
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
Here is the shareable link to Dan's paper: https://t.co/VFdjXRrL03
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
@XiruiH lol
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
Another great study using chemoproteomics and a covalent strategy to discover and recruit a new E3 ligase. Great to see this live from the preprint last year. Big day for #targetedproteindegradation! Congrats @DanNomura lab and co!!
RT @j_sprads: So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_C…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @j_sprads: So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_C…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @j_sprads: So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_C…
RT @j_sprads: So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_C…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
Amazing work to elucidate the mechanism of RNF114 recruitment, subsequent downstream effects, and now another E3 ligase recruiter for the #PROTAC chemistry toolbox!
RT @OlzmannLab: New research in @nchembio from @DanNomura and Tom Maimone identifies the anticancer mechanism of nimbolide and describes a…
New research in @nchembio from @DanNomura and Tom Maimone identifies the anticancer mechanism of nimbolide and describes a new degrader. Happy to have contributed in a small way to this beautiful study. @berkeleyMCB @UCB_Chemistry @BerkeleyMetBio https://t
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @CarolynBertozzi: Beautiful work, I have been looking forward to the final publication after the preview on @ChemRxiv and #ACS2019 Orlan…
Beautiful work, I have been looking forward to the final publication after the preview on @ChemRxiv and #ACS2019 Orlando. Congratulations to team @UCB_Chemistry and @NovartisScience
RT @j_sprads: So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_C…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
So excited to see this paper in print! What a fun project to work on with great scientists across @NovartisScience and @UCB_Chemistry
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
RT @DanNomura: Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide fo…
Our paper with @NovartisScience and Tom Maimone's lab @UCBerkeley on Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation applications is out in @nchembio !! Congrats to our grad student @j_sprads !! https://t.co/ySlNlGaKbG