Title |
A new chapter: hematopoietic stem cells are direct players in immunity
|
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Published in |
Cell & Bioscience, October 2011
|
DOI | 10.1186/2045-3701-1-33 |
Pubmed ID | |
Authors |
Junke Zheng, Chun Song, Cheng Cheng Zhang |
Abstract |
Several lines of evidence support the hypothesis that hematopoietic stem cells (HSCs) directly interact with the immune system and have potential for immune privilege. Although the microenvironment or niche provides protection for HSCs from immune attack, HSCs are also capable of interacting with the immune system as signal "providers" and signal "receivers". On the one hand, HSCs display surface immune inhibitory molecules to evade the attack from the innate and adaptive immune systems; on the other hand, HSCs are capable of directly sensing the signals from the immune system through their surface receptors. Thus, HSCs are important direct players in the immune system. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 4 | 18% |
Student > Ph. D. Student | 4 | 18% |
Student > Master | 3 | 14% |
Student > Bachelor | 2 | 9% |
Lecturer | 2 | 9% |
Other | 3 | 14% |
Unknown | 4 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 32% |
Agricultural and Biological Sciences | 6 | 27% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Mathematics | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Other | 2 | 9% |
Unknown | 4 | 18% |