@IgorUlitsky Perhaps work from @sandberglab may help https://t.co/kOHvvAUrLa
@dominic_grun @cartalop @GenomeBiology @ReynaERosales @Nina_CabezasW How does VarID2 method relate to the stochastic dynamics of RNA production/removal (https://t.co/qMmJBWM6iF @GorinGennady) and to the bursting rates (https://t.co/FRE3qAnHTQ)?
"Repetition adds no quantity of present force, no intensity; it reproduces the same impression: yet it has the power of fraying" Derrida pg 78 FSW, WD Wow enhancer dynamics in genomic regulatory contexts probably drive repetition of gene expression http
RT @vitaliikl: @slavov_n @arjunrajlab This paper by @AntonJohnAnton could give a partial answer: https://t.co/FRE3qAnHTQ. The magnitude of…
RT @vitaliikl: @slavov_n @arjunrajlab This paper by @AntonJohnAnton could give a partial answer: https://t.co/FRE3qAnHTQ. The magnitude of…
RT @vitaliikl: @slavov_n @arjunrajlab This paper by @AntonJohnAnton could give a partial answer: https://t.co/FRE3qAnHTQ. The magnitude of…
RT @vitaliikl: @slavov_n @arjunrajlab This paper by @AntonJohnAnton could give a partial answer: https://t.co/FRE3qAnHTQ. The magnitude of…
@slavov_n @arjunrajlab This paper by @AntonJohnAnton could give a partial answer: https://t.co/FRE3qAnHTQ. The magnitude of differences in burst frequency rate across genes is much greater than differences in degradation rate across genes.
TIL about transcriptional bursting. Freakin' fascinating! Who knew? (Fine, maybe y'all knew. I didn't know.) #todayilearned #genetics #kinetics https://t.co/zzFdvJFvXr
Maybe a little late to share: "Notably, we provide transcriptome-wide evidence that enhancers control burst frequencies, and demonstrate that cell-type-specific gene expression is primarily shaped by changes in burst frequencies." https://t.co/gqxfPlVakm
Genomic encoding of transcriptional burst kinetics | Nature https://t.co/E6MJ0cd3aL
@Alfons_Valencia Interesting, how does this relate to Larrson et al., 2019 paper who show core promoters and enhancers control transcriptional burst size and frequency respectively and cell-type-specific gene expression is primarily shaped by changes in bu
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
マウスシングルセルRNA-seqのデータを使った転写バーストの解析。やっぱりエンハンサーが制御してるのはバーストのsizeじゃなくてfrequencyなんだな、そしてfrequencyと発現量は相関する。 先月のNature。 https://t.co/WKWtWC5jWK
RT @AntonJohnAnton: We used single-cell RNA sequencing to uncover determinants of transcriptional burst kinetics in mammalian cells. Read a…
We used single-cell RNA sequencing to uncover determinants of transcriptional burst kinetics in mammalian cells. Read at https://t.co/jfryMUCONW!
Great work of @sandberglab on details of enhancer, promoter and transcriptional dynamics. #VisualAbstract #Genomics More: https://t.co/ieGg7qwN1h https://t.co/QLRvpzzHFu
Great genome wide paper showing that transcription burst frequency is primarily encoded in enhancers and burst size in core promoters. https://t.co/i5CXCUFvsT
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
Finally managed to get round to reading this fascinating paper from Rickard Sandberg's group using allele specific scRNA-seq to study transcriptional burst kinetics. Amazing work - a powerful approach to study the impact of DNA variants on transcription.
Genomic encoding of transcriptional burst kinetics https://t.co/BtARzycbS3 $$ https://t.co/W87zqJmgbp
Genomic encoding of transcriptional burst kinetics https://t.co/SMcmw1hztY
Amazing paper. Dr. RenBing!
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
RT @pandolfatto: Genomic encoding of transcriptional burst kinetics. https://t.co/nx5HqmEUg4
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
Genomic encoding of transcriptional burst kinetics. https://t.co/nx5HqmEUg4
RT @CircadianClocks: Genomic encoding of transcriptional burst kinetics | Nature https://t.co/RJ9lEe7bW4
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
https://t.co/44DaxB2gyD Enhancers dictate transcriptional burst frequency, and core promoters - burst size...
RT @CircadianClocks: Genomic encoding of transcriptional burst kinetics | Nature https://t.co/RJ9lEe7bW4
Genomic encoding of transcriptional burst kinetics | Nature https://t.co/RJ9lEe7bW4
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
RT @mirimiam: “burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
“burst frequency is primarily encoded in enhancers and burst size in core promoters” https://t.co/cXmNoGaf8V
Sometimes I feel that the code of life reads like music. I wonder whether #Tolkien knew it...
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
Core promoter elements and enhancers regulate the size and frequency, respectively, of transcriptional bursting. https://t.co/otnIrtnMm7
RT @notSoJunkDNA: Genomic encoding of transcriptional burst kinetics https://t.co/4a6zv9HO2P https://t.co/4qQKHisbbm
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
RT @daSpliceIsRight: what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https:/…
what better way to kick off 2019 than with this exciting paper on transcriptional bursting from @sandberglab ! https://t.co/FkbuQ1RImh
RNA polymerase transcriptional burst frequency controlled by enhancers and promoters determine burst size. #scRNAseq #RNAseq #QBio #transcription https://t.co/K3W8zVCP9H
Last week in @nature, an interesting paper about the kinetics of transcription from @karolinskainst and @UCSanDiego https://t.co/CAkUxzuDEr
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
Genomic encoding of transcriptional burst kinetics https://t.co/ZnrczBbfyU via @nresearchnews
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
Pretty! https://t.co/24NOnpZLE2
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
burst frequencyはエンハンサー、 burst sizeは中核プロモーター。Genomic encoding of transcriptional burst kinetics https://t.co/ImH8Yuekxj
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
Cool work!!
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
RT @lorenzpasquali: SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional p…
SC and AS RNA sequencing to understand transcription dynamics: -Promoter sequence composition affect transcriptional pulsing size. -Enhancers modulate pulse frequency to shape cell-type-specific gene expression https://t.co/SZ25wtelNE @nature
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @Magda_Skipper: Allele-specific single-cell RNA sequencing provides insights into transcription kinetics - core promoter sequences affec…
RT @jaybradner: Enhancers drive cell-type (and surely cell-state) specific bursts of transcription. Gorgeous study, powerful especially for…