New from #The_MRC https://t.co/ZR2iXNvHvs A dynamic three step mechanism drives the HIV-1 prefusion reaction
@eli_fazeli @poutreda Sergi Padilla in Oxford we had a nice paper last year based 100% on microscopy. https://t.co/QgZGv3XSDU
A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction. https://t.co/KMVgRMd7RM
@barrosolab @Becker_Hickl @PhotoBioLab @LeicaMicro @PicoQuant @drmgmonaghan We did this in Oxford with Sergi Padilla @poutreda for endogenous expression levels last year https://t.co/ZP9b3CxfkL
Today testing some nanoscopy in #TIRF with @abbelight in Paris. To see if we can redo our dSTORM data from our latest paper on HIV entry https://t.co/ZP9b3CxfkL https://t.co/DUWM5nhyxW
@Fran_Bottanelli Do you have anyone with FRET/FLIM experience around ? If you care only at protein-protein interactions another option is cross correlation Number and Brightness (ccN&B) this does not need a specific "add on". Example from our lab https
@rita_strack If you have an hour to spare come down to @HumanGeneticsOx right around the corner to visit us ! We can show you how the quantitative imaging in our latest @NatureSMB came to light https://t.co/ZP9b3CxfkL
So true - integrating all of that together makes for a terrific approach
RT @hdrummer1: New insights into HIV fusion. https://t.co/btD4xev195
RT @hdrummer1: New insights into HIV fusion. https://t.co/btD4xev195
RT @hdrummer1: New insights into HIV fusion. https://t.co/btD4xev195
RT @tngo715: The time-resolved mechanism and stoichometry of HIV pre-fusion complex formation - HIV envelope with CD4 and chemokine co-rece…
A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction. https://t.co/zErhEm5QMQ
A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction. https://t.co/nuQj0dqdZv https://t.co/SuDEWBv2kB
A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction. by Iliopoulou M, Nolan R, Alvarez L, Watanabe Y, Coomer CA, Jakobsdottir GM, Bowden TA, Padilla-Parra S https://t.co/RzshGdH0bV
RT @Ikerbasque: Nuevo artículo de Sergi Padilla, investigador @Ikerbasque en @biocrucesHRI en @NatureSMB sobre el mecanismo molecular del p…
RT @Ikerbasque: Nuevo artículo de Sergi Padilla, investigador @Ikerbasque en @biocrucesHRI en @NatureSMB sobre el mecanismo molecular del p…
RT @Ikerbasque: Nuevo artículo de Sergi Padilla, investigador @Ikerbasque en @biocrucesHRI en @NatureSMB sobre el mecanismo molecular del p…
Nuevo artículo de Sergi Padilla, investigador @Ikerbasque en @biocrucesHRI en @NatureSMB sobre el mecanismo molecular del proceso de fusión del VIH a la célula huésped. Puede ayudar a crear terapias para inhibir los procesos de infección por VIH. Más info:
The time-resolved mechanism and stoichometry of HIV pre-fusion complex formation - HIV envelope with CD4 and chemokine co-receptors CCR5 and CXCR4. Awesome use of single molecule fluorescence to study protein:protein dynamics https://t.co/k8yryaQ6gz
From what I know this is the 1st time resolved stoichiometry of protein-protein interactions in live cells at the membrane; 1st also in the context of host-pathogen -> stoichiometry of viral induced host receptors changes on entry (HIV here).
Congrats Maro, sergi, and all others!! Recommended read. https://t.co/Wni8b9Ad6N
Congratulations to Maro Iliopoulou, Rory Nolan, Sergi Padilla-Parra and team for their latest work "A dynamic three-step mechanism drives the HIV-1 pre-fusion reaction" in @NatureSMB! https://t.co/AycOzTZuHN