Showing items 1–100
EVOLVED CYTOSINE DEAMINASES AND METHODS OF EDITING DNA USING SAME
Application WO-2024040083-A1
World Intellectual Property Organisation (WIPO)
Genome engineering with Type I CRISPR systems in eukaryotic cells
Grant US-11905526-B2
United States of America
Genetic correction of mutated genes
Grant US-11898176-B2
United States of America
Tale RVD specifically recognizing DNA base modified by methylation and application thereof
Grant US-11897920-B2
United States of America
Highly sensitive in vitro assays to define substrate preferences and sites of nucleic-acid…
Grant US-11898203-B2
United States of America
Materials and methods for treatment of glycogen storage disease type 1A
Grant US-11866727-B2
United States of America
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-11859220-B2
United States of America
Materials and methods for treatment of alpha-1 antitrypsin deficiency
Grant US-11851653-B2
United States of America
Systems and methods for the treatment of hemoglobinopathies
Grant US-11851690-B2
United States of America
Highly sensitive in vitro assays to define substrate preferences and sites of nucleic…
Grant US-11845987-B2
United States of America
Materials and methods for treatment of pain related disorders
Grant US-11801313-B2
United States of America
BCL11A guide delivery
Grant US-11788087-B2
United States of America
NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
Application EP-4257696-A2
European Patent Office
NOVEL CRISPR DNA AND RNA TARGETING ENZYMES AND SYSTEMS
Application EP-4253551-A2
European Patent Office
Compositions and methods to treating hemoglobinopathies
Grant US-11739329-B2
United States of America
Methods for detecting site-specific and spurious genomic deamination induced by base…
Grant US-11725228-B2
United States of America
METHODS FOR INCREASING FETAL HEMOGLOBIN CONTENT BY EDITING THE +55-KB REGION OF THE…
Application WO-2023099591-A1
World Intellectual Property Organisation (WIPO)
CRISPR nuclease
Grant US-11666641-B2
United States of America
CRISPR-associated systems and components
Grant US-11667904-B2
United States of America
CRISPR-CAS12i systems
Grant US-11649444-B1
United States of America
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-11624058-B2
United States of America
Gene knockout method
Grant US-11624077-B2
United States of America
NOVEL CRISPR ENZYMES AND SYSTEMS
Application EP-4159856-A1
European Patent Office
Targeting BCL11A enhancer functional regions for fetal hemoglobin reinduction
Grant US-11572543-B2
United States of America
Materials and methods for treatment of hemoglobinopathies
Grant US-11566236-B2
United States of America
Materials and methods for treatment of friedreich ataxia and other related disorders
Grant US-11564997-B2
United States of America
Materials and methods for treatment of Spinocerebellar Ataxia Type 1 (SCA1) and other…
Grant US-11559588-B2
United States of America
Targeting BCL11A distal regulatory elements for fetal hemoglobin reinduction
Grant US-11542493-B2
United States of America
Endogenous Gag-based capsids and uses thereof
Grant US-11505578-B2
United States of America
Materials and methods for treatment of pain related disorders
Grant US-11459587-B2
United States of America
Endogenous Gag-based capsids and uses thereof
Grant US-11447527-B2
United States of America
ENGINEERED CRISPR/CAS13 SYSTEM AND USES THEREOF
Application WO-2022188039-A1
World Intellectual Property Organisation (WIPO)
COMPOSITIONS AND METHODS FOR THE TREATMENT OF HEMOGLOBINOPATHIES
Application EP-4053277-A1
European Patent Office
Materials and methods for treatment of primary hyperoxaluria type 1 (PH1) and other…
Grant US-11407997-B2
United States of America
MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES
Application US-20220211874-A1
United States of America
PROTECTED GUIDE RNAS (PGRNAS)
Application EP-3985115-A1
European Patent Office
ENGINEERED CRISPR/CAS13 SYSTEM AND USES THEREOF
Application WO-2022068912-A1
World Intellectual Property Organisation (WIPO)
BIFUNCTIONAL LENTIVIRAL VECTORS ALLOWING THE BS-GLOBIN SILENCING AND EXPRESSION OF AN ANTI…
Application WO-2022063754-A1
World Intellectual Property Organisation (WIPO)
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-11286468-B2
United States of America
Materials and methods for treatment of hemoglobinopathies
Grant US-11268077-B2
United States of America
Vectors and compositions for treating hemoglobinopathies
Grant US-11261441-B2
United States of America
Method for improving gene knockout efficiency
Application CN-114032240-A
China
CRISPR/CAS-related methods and compositions for treating sickle cell disease
Grant US-11242525-B2
United States of America
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-11220678-B2
United States of America
Materials and methods for treatment of Amyotrophic Lateral Sclerosis (ALS) and other…
Grant US-11174469-B2
United States of America
Compositions and methods for epigenome editing
Grant US-11155796-B2
United States of America
PROTECTED GUIDE RNAS (PGRNAS)
Application EP-3889260-A1
European Patent Office
Compositions and methods to treating hemoglobinopathies
Grant US-11124794-B2
United States of America
Materials and methods for treatment of hereditary haemochromatosis
Grant US-11083799-B2
United States of America
Full interrogation of nuclease DSBs and sequencing (FIND-seq)
Grant US-11028429-B2
United States of America
METHOD FOR EDITING BCL11A GENE IN HAEMATOPOIETIC STEM/PROGENITOR CELLS
Application WO-2021037232-A1
World Intellectual Property Organisation (WIPO)
TARGETING BCL11A ENHANCER FUNCTIONAL REGIONS FOR FETAL HEMOGLOBIN REINDUCTION
Application EP-3763814-A1
European Patent Office
METHODS FOR TREATING METABOLIC DISORDERS BY TARGETING ADCY5
Application WO-2020243661-A1
World Intellectual Property Organisation (WIPO)
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-10808233-B2
United States of America
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-10767168-B2
United States of America
CRISPR HAVING OR ASSOCIATED WITH DESTABILIZATION DOMAINS
Application EP-3702456-A1
European Patent Office
TARGETING BCL11A ENHANCER FUNCTIONAL REGIONS FOR FETAL HEMOGLOBIN REINDUCTION
Grant EP-3294873-B1
European Patent Office
Comprehensive in vitro reporting of cleavage events by sequencing (CIRCLE-seq)
Grant US-10738303-B2
United States of America
Materials and methods for treatment of hemoglobinopathies
Grant US-10738305-B2
United States of America
CRISPR-ASSOCIATED TRANSPOSASE SYSTEMS AND METHODS OF USE THEREOF
Application WO-2020131862-A1
World Intellectual Property Organisation (WIPO)
METHODS FOR IDENTIFYING NEOANTIGENS
Application WO-2020131586-A2
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR ENZYMES AND SYSTEMS
Application EP-3666895-A1
European Patent Office
Compositions and methods to treating hemoglobinopathies
Grant US-10662429-B2
United States of America
METHODS FOR MODULATING DNA REPAIR OUTCOMES
Application EP-3653709-A1
European Patent Office
METHODS AND COMPOSITIONS FOR MODULATING MICROENVIRONMENT
Application WO-2020081730-A2
World Intellectual Property Organisation (WIPO)
METHOD OF IDENTIFYING AND TREATING A PERSON HAVING A PREDISPOSITION TO OR AFFLICTED WITH…
Application EP-3626832-A2
European Patent Office
METHODS FOR INCREASING FETAL HEMOGLOBIN CONTENT IN EUKARYOTIC CELLS AND USES THEREOF FOR…
Application WO-2020053224-A1
World Intellectual Property Organisation (WIPO)
METHODS AND COMPOSITIONS FOR OPTOCHEMICAL CONTROL OF CRISPR-CAS9
Application WO-2020041380-A1
World Intellectual Property Organisation (WIPO)
DEGRADATION DOMAIN MODIFICATIONS FOR SPATIO-TEMPORAL CONTROL OF RNA-GUIDED NUCLEASES
Application WO-2020041387-A1
World Intellectual Property Organisation (WIPO)
NOVEL CAS12B ENZYMES AND SYSTEMS
Application WO-2020033601-A1
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
Application WO-2020018142-A1
World Intellectual Property Organisation (WIPO)
Genomewide unbiased identification of DSBs evaluated by sequencing (GUIDE-seq)
Grant US-10501794-B2
United States of America
METHODS AND COMPOSITIONS FOR DETECTING AND MODULATING MICROENVIRONMENT GENE SIGNATURES…
Application WO-2019232542-A2
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR-ASSOCIATED SYSTEMS AND COMPONENTS
Application WO-2019222555-A1
World Intellectual Property Organisation (WIPO)
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Application US-10479982-B2
United States of America
Targeting BCL11A distal regulatory elements for fetal hemoglobin reinduction
Grant US-10472619-B2
United States of America
SEQUENCING-BASED PROTEOMICS
Application WO-2019210268-A2
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR DNA AND RNA TARGETING ENZYMES AND SYSTEMS
Application WO-2019178428-A1
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR DNA TARGETING ENZYMES AND SYSTEMS
Application WO-2019178427-A1
World Intellectual Property Organisation (WIPO)
MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES
Application WO-2019150196-A1
World Intellectual Property Organisation (WIPO)
TARGETING BCL11A DISTAL REGULATORY ELEMENTS FOR FETAL HEMOGLOBIN REINDUCTION
Application EP-3502240-A1
European Patent Office
METHODS AND COMPOSITIONS FOR TREATING CANCER BY TARGETING THE CLEC2D-KLRB1 PATHWAY
Application WO-2019094983-A1
World Intellectual Property Organisation (WIPO)
Compositions and methods to treating hemoglobinopathies
Grant US-10287588-B2
United States of America
SYNTHETIC RNAS AND METHODS OF USE
Application WO-2019087113-A1
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND COMPONENTS
Application WO-2019090175-A1
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND COMPONENTS
Application WO-2019090173-A1
World Intellectual Property Organisation (WIPO)
NOVEL CRISPR-ASSOCIATED TRANSPOSON SYSTEMS AND COMPONENTS
Application WO-2019090174-A1
World Intellectual Property Organisation (WIPO)
METHOD FOR IMPROVING FETAL HEMOGLOBIN EXPRESSION
Application WO-2019080917-A1
World Intellectual Property Organisation (WIPO)
METHOD FOR INCREASING FETAL HEMOGLOBIN EXPRESSION LEVEL
Application WO-2019080920-A1
World Intellectual Property Organisation (WIPO)
MATERIALS AND METHODS FOR TREATMENT OF HEMOGLOBINOPATHIES
Application WO-2019081982-A1
World Intellectual Property Organisation (WIPO)
SYSTEMS, METHODS, AND COMPOSITIONS FOR TARGETED NUCLEIC ACID EDITING
Application WO-2019060746-A1
World Intellectual Property Organisation (WIPO)
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-10202589-B2
United States of America
NOVEL CRISPR RNA TARGETING ENZYMES AND SYSTEMS AND USES THEREOF
Application WO-2019006471-A2
World Intellectual Property Organisation (WIPO)
CRISPR/CAS-ADENINE DEAMINASE BASED COMPOSITIONS, SYSTEMS, AND METHODS FOR TARGETED…
Application WO-2019005884-A1
World Intellectual Property Organisation (WIPO)
METHODS FOR THE TREATMENT OF DISEASE WITH GENE EDITING SYSTEMS
Application WO-2019003193-A1
World Intellectual Property Organisation (WIPO)
METHODS AND COMPOSITIONS FOR DETERMINATION OF MUTATIONS IN SINGLE REPLICATION EVENTS
Application WO-2018209145-A1
World Intellectual Property Organisation (WIPO)
TARGETING BCL11A ENHANCER FUNCTIONAL REGIONS FOR FETAL HEMOGLOBIN REINDUCTION
Application EP-3294873-A4
European Patent Office
METHODS AND COMPOSITIONS FOR ENHANCING GENE EDITING
Application WO-2018083606-A1
World Intellectual Property Organisation (WIPO)
Engineered CRISPR-Cas9 nucleases with altered PAM specificity
Grant US-9944912-B2
United States of America
Showing items 1–100