| Title |
Deep brain stimulation for obsessive-compulsive disorder and treatment-resistant depression: systematic review
|
|---|---|
| Published in |
BMC Research Notes, March 2010
|
| DOI | 10.1186/1756-0500-3-60 |
| Pubmed ID | |
| Authors |
Shaheen E Lakhan, Enoch Callaway |
| Abstract |
In spite of advances in psychotherapy and pharmacotherapy, there are still a significant number of patients with depression and obsessive-compulsive disorder that are not aided by either intervention. Although still in the experimental stage, deep brain stimulation (DBS) offers many advantages over other physically-invasive procedures as a treatment for these psychiatric disorders. The purpose of this study is to systematically review reports on clinical trials of DBS for obsessive-compulsive disorder (OCD) and treatment-resistant depression (TRD). Locations for stimulation, success rates and effects of the stimulation on brain metabolism are noted when available. The first observation of the effects of DBS on OCD and TRD came in the course of using DBS to treat movement disorders. Reports of changes in OCD and depression during such studies are reviewed with particular attention to electrode locations and associated adverse events; although these reports were adventitious observations rather than planned. Subsequent studies have been guided by more precise theories of structures involved in DBS and OICD. This study suggests stimulation sites and prognostic indicators for DBS. We also briefly review tractography, a relatively new procedure that holds great promise for the further development of DBS. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 3 | 2% |
| Netherlands | 2 | 1% |
| Germany | 2 | 1% |
| Turkey | 1 | <1% |
| France | 1 | <1% |
| Brazil | 1 | <1% |
| South Africa | 1 | <1% |
| Canada | 1 | <1% |
| Russia | 1 | <1% |
| Other | 3 | 2% |
| Unknown | 121 | 88% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 20% |
| Student > Ph. D. Student | 24 | 18% |
| Student > Bachelor | 16 | 12% |
| Other | 15 | 11% |
| Student > Master | 13 | 9% |
| Other | 30 | 22% |
| Unknown | 12 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 30% |
| Psychology | 22 | 16% |
| Agricultural and Biological Sciences | 17 | 12% |
| Neuroscience | 17 | 12% |
| Engineering | 8 | 6% |
| Other | 12 | 9% |
| Unknown | 20 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2022.
All research outputs
#1,572,153
of 23,570,677 outputs
Outputs from BMC Research Notes
#173
of 4,304 outputs
Outputs of similar age
#5,583
of 94,995 outputs
Outputs of similar age from BMC Research Notes
#2
of 13 outputs
Altmetric has tracked 23,570,677 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,304 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.