| Title |
Co-expression of KCNE2 and KChIP2c modulates the electrophysiologi-cal properties of Kv4.2 current in COS-7 cells
|
|---|---|
| Published in |
Acta Pharmacologica Sinica, June 2008
|
| DOI | 10.1111/j.1745-7254.2008.00804.x |
| Pubmed ID | |
| Authors |
Wen-juan LIU, Hai-tang WANG, Wei-wei Chen, Jian-xin DENG, Yong JIANG, Jie LIU |
| Abstract |
Several beta-subunits have been suggested to modulate the electrophysiological properties of the transient outward current (I(to)) in cardiac myocytes, including the obligatory beta-subunit K+-channel interacting protein (KChIP2) and KCNE2. However, neither KChIP2 nor KCNE2 modulation of Kv4.x (x=2 and/or 3) can fully recapitulate the electrophysiological properties of native I(to). The present study is to investigate how I(to) current is modulated when both KChIP2 and KCNE2 are coexpressed. |
Mendeley readers
The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 5 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 2 | 40% |
| Professor > Associate Professor | 1 | 20% |
| Student > Bachelor | 1 | 20% |
| Student > Master | 1 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 3 | 60% |
| Chemistry | 2 | 40% |