| Title |
Precision genome engineering through adenine and cytosine base editing
|
|---|---|
| Published in |
Nature Plants, February 2018
|
| DOI | 10.1038/s41477-018-0115-z |
| Pubmed ID | |
| Authors |
Jin-Soo Kim |
| Abstract |
Adenine base editors (ABEs), composed of an engineered deaminase and a catalytically impaired CRISPR-Cas9 variant, are powerful new tools for targeted base editing in cells and organisms. Together with cytosine base editors (CBEs), ABEs enable single-nucleotide conversions cleanly, efficiently and reversibly without double-stranded DNA cleavage, advancing genome editing in a new dimension. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 152 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 22% |
| Student > Ph. D. Student | 26 | 17% |
| Student > Bachelor | 12 | 8% |
| Student > Master | 12 | 8% |
| Student > Doctoral Student | 7 | 5% |
| Other | 21 | 14% |
| Unknown | 41 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 57 | 38% |
| Biochemistry, Genetics and Molecular Biology | 33 | 22% |
| Chemical Engineering | 2 | 1% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 1% |
| Medicine and Dentistry | 2 | 1% |
| Other | 7 | 5% |
| Unknown | 49 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2024.
All research outputs
#3,223,622
of 25,382,440 outputs
Outputs from Nature Plants
#1,180
of 2,042 outputs
Outputs of similar age
#63,829
of 343,860 outputs
Outputs of similar age from Nature Plants
#21
of 44 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,042 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 50.6. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 343,860 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.