Title |
Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial
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Published in |
Journal of Perinatology, December 2016
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DOI | 10.1038/jp.2016.222 |
Pubmed ID | |
Authors |
J S Mercer, D A Erickson-Owens, J Collins, M O Barcelos, A B Parker, J F Padbury |
Abstract |
The objective of the study was to measure the effects of a 5-min delay (DCC) versus immediate cord clamping (ICC) on residual placental blood volume (RPBV) at birth, and hemoglobin and serum bilirubin at 24 to 48 h of age. In this prospective randomized controlled trial, 73 women with term (37 to 41 weeks) singleton fetuses were randomized to DCC (⩾5 min; n=37) or ICC (<20 s; n=36). Maternal and infant demographics were not different between the groups. Mean cord clamping time was 303±121 (DCC) versus 23±59 (ICC) s (P<0.001) with 10 protocol violations. Cord milking was the proxy for DCC (n=11) when the provider could not wait. Infants randomized to DCC compared with ICC had significantly less RPBV (20.0 versus 30.8 ml kg(-1), P<0.001), higher hemoglobin levels (19.4 versus 17.8 g dl(-1), P=0.002) at 24 to 48 h, with no difference in bilirubin levels. Term infants had early hematological advantage of DCC without increases in hyperbilirubinemia or symptomatic polycythemia.Journal of Perinatology advance online publication, 8 December 2016; doi:10.1038/jp.2016.222. |
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Canada | 5 | 24% |
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India | 1 | 5% |
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Demographic breakdown
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Scientists | 5 | 24% |
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Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 29 | 18% |
Student > Master | 25 | 16% |
Student > Postgraduate | 11 | 7% |
Other | 8 | 5% |
Researcher | 7 | 4% |
Other | 26 | 17% |
Unknown | 51 | 32% |
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Business, Management and Accounting | 4 | 3% |
Biochemistry, Genetics and Molecular Biology | 3 | 2% |
Sports and Recreations | 2 | 1% |
Other | 11 | 7% |
Unknown | 55 | 35% |