@shaharsu I’m glad you asked that! These proteins (NHE1, AE2, CA2, PI3Ky) are commonly called ubiquitous but besides NHE1 they’re understudied. NHE1 localizes to the leading edge in many different migrating cells incl cancer cells, immune cells, microglia.
RT @KKLabJHU: Pleased to see our recent @NatureComms article with @SXS_biophysics,@KaustavBera11,@mistrigr featured in Editors’ Highlights…
RT @NatureComms: .@KKLabJHU and colleagues show that SWELL1 and NHE1 regulate cell volume to propel confined cells, favouring breast cancer…
RT @KKLabJHU: Pleased to see our recent @NatureComms article with @SXS_biophysics,@KaustavBera11,@mistrigr featured in Editors’ Highlights…
RT @KKLabJHU: Pleased to see our recent @NatureComms article with @SXS_biophysics,@KaustavBera11,@mistrigr featured in Editors’ Highlights…
RT @KKLabJHU: Pleased to see our recent @NatureComms article with @SXS_biophysics,@KaustavBera11,@mistrigr featured in Editors’ Highlights…
Pleased to see our recent @NatureComms article with @SXS_biophysics,@KaustavBera11,@mistrigr featured in Editors’ Highlights of Cancer! https://t.co/Ljf0G2FGbc We delineate roles of ion channels & transporters in breast cancer cell migration & meta
RT @NatureComms: .@KKLabJHU and colleagues show that SWELL1 and NHE1 regulate cell volume to propel confined cells, favouring breast cancer…
RT @NatureComms: .@KKLabJHU and colleagues show that SWELL1 and NHE1 regulate cell volume to propel confined cells, favouring breast cancer…
New research explores how cancer cells spread in human body @binghamtonu @NatureComms https://t.co/wxBGbX06eT https://t.co/W5tw4K4b2d
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
.@KKLabJHU and colleagues show that SWELL1 and NHE1 regulate cell volume to propel confined cells, favouring breast cancer cell extravasation and metastasis @SXS_biophysics https://t.co/aa5EH0SAyf
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @mistrigr: Proud to be part of this exciting work on the role of SWELL1 and NHE1 in breast cancer cell migration and metastasis. Congrat…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
Proud to be part of this exciting work on the role of SWELL1 and NHE1 in breast cancer cell migration and metastasis. Congrats to @KKLabJHU and @SXS_biophysics! 🎉
Privileged to be a part of this publication @NatureComms where we show that ion channels on the cell membrane, which typically regulate cancer cell volume, also help them migrate and metastasize in vivo 🤩! Thanks to @KKLabJHU @SXS_biophysics @INBT_JHU for
RT @KKLabJHU: Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear c…
Pleased to share our #NCI funded work @NatureComms. Optogenetics & math modeling show that SWELL1 polarization at cell rear confers migration direction. SWELL1 & NHE1 coordinate to facilitate breast cancer migration, extravasation and metastasis. @
New article: Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis https://t.co/GC4XasLTVp #breastcancer #oncology https://t.co/hiU5paOxmu
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
🆕 Brand-new in @NatureComms! Researchers at Konstantopoulos Lab (@KKLabJHU) and collaborators studied the physiological relevance of the Osmotic Engine Model, and identify 🔍 two of the elusive molecules mediating cell rear shrinkage. #metastasis 🔓 https
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
RT @SXS_biophysics: Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Cong…
Definitive exploration of the Osmotic Engine Model of cell migration using optogenetic control of NHE1 and SWELL1. Congrats to Yuqi and Yizeng, and all of our collaborators! https://t.co/clRwTCRpKB