High efficiency base editors comprising Gam Grant US-11932884-B2 United States of America 19 Mar 2024
Methods and compositions for simultaneous editing of both strands of a target double-strand… Grant US-11912985-B2 United States of America 27 Feb 2024
Editing of CCR2 receptor gene to protect against HIV infection Grant US-11820969-B2 United States of America 21 Nov 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11795452-B2 United States of America 24 Oct 2023
Methods and compositions for evolving base editors using phage-assisted continuous… Grant US-11732274-B2 United States of America 22 Aug 2023
Adenosine nucleobase editors and uses thereof Grant US-11702651-B2 United States of America 18 Jul 2023
Programmable CAS9-recombinase fusion proteins and uses thereof Grant US-11661590-B2 United States of America 30 May 2023
Methods and compositions for prime editing nucleotide sequences Grant US-11643652-B2 United States of America 09 May 2023
CAS9 proteins including ligand-dependent inteins Grant US-11578343-B2 United States of America 14 Feb 2023
Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and… Grant US-11560566-B2 United States of America 24 Jan 2023
Incorporation of unnatural amino acids into proteins using base editing Grant US-11542509-B2 United States of America 03 Jan 2023
DNase H activity of Neisseria meningitidis Cas9 Grant US-11453864-B2 United States of America 27 Sep 2022
Methods and compositions for prime editing nucleotide sequences Grant US-11447770-B1 United States of America 20 Sep 2022
CRISPR-related methods and compositions with governing gRNAS Grant US-11390887-B2 United States of America 19 Jul 2022
Detection of gene loci with CRISPR arrayed repeats and/or polychromatic single guide… Grant US-11390908-B2 United States of America 19 Jul 2022
High efficiency base editors comprising Gam Grant US-11319532-B2 United States of America 03 May 2022
Nucleobase editors comprising nucleic acid programmable DNA binding proteins Grant US-11268082-B2 United States of America 08 Mar 2022
Fusions of Cas9 domains and nucleic acid-editing domains Grant US-11053481-B2 United States of America 06 Jul 2021
Engineered transcription activator-like effector (TALE) domains and uses thereof Grant US-11046948-B2 United States of America 29 Jun 2021
Adenosine nucleobase editors and uses thereof Grant US-10947530-B2 United States of America 16 Mar 2021
Precise microbiota engineering at the cellular level Grant US-10752906-B2 United States of America 25 Aug 2020
Editing of CCR5 receptor gene to protect against HIV infection Grant US-10745677-B2 United States of America 18 Aug 2020
CRISPR-based genome modification and regulation Grant US-10745716-B2 United States of America 18 Aug 2020
CRISPR-based genome modification and regulation Grant US-10731181-B2 United States of America 04 Aug 2020
CAS9 proteins including ligand-dependent inteins Grant US-10704062-B2 United States of America 07 Jul 2020
CRISPR-related methods and compositions with governing gRNAs Grant US-10640788-B2 United States of America 05 May 2020
Methods for identifying a target site of a CAS9 nuclease Grant US-10508298-B2 United States of America 17 Dec 2019
DELIVERY, ENGINEERING AND OPTIMIZATION OF SYSTEMS, METHODS AND COMPOSITIONS FOR TARGETING… Grant EP-3011032-B1 European Patent Office 16 Oct 2019
Evaluation and improvement of nuclease cleavage specificity Grant US-10323236-B2 United States of America 18 Jun 2019
SELF-INACTIVATING (SIN) CRISPR/CAS OR CRISPR/CPF1 SYSTEMS AND USES THEREOF Application WO-2019092505-A1 World Intellectual Property Organisation (WIPO) 16 May 2019
CRISPR/CAS SYSTEMS FOR TREATMENT OF DMD Application WO-2019092507-A2 World Intellectual Property Organisation (WIPO) 16 May 2019
Using programmable DNA binding proteins to enhance targeted genome modification Grant US-10266851-B2 United States of America 23 Apr 2019
Engineered transcription activator-like effector (TALE) domains and uses thereof Application US-10227581-B2 United States of America 12 Mar 2019
CRISPR-related methods and compositions with governing gRNAS Grant US-10190137-B2 United States of America 29 Jan 2019
Adenosine nucleobase editors and uses thereof Grant US-10113163-B2 United States of America 30 Oct 2018
NUCLEOBASE EDITORS COMPRISING NUCLEIC ACID PROGRAMMABLE DNA BINDING PROTEINS Application WO-2018176009-A1 World Intellectual Property Organisation (WIPO) 27 Sep 2018
CAS9 proteins including ligand-dependent inteins Grant US-10077453-B2 United States of America 18 Sep 2018
CRISPR-related methods and compositions with governing gRNAS Grant US-9834791-B2 United States of America 05 Dec 2017
DETECTION OF GENE LOCI WITH CRISPR ARRAYED REPEATS AND/OR POLYCHROMATIC SINGLE GUIDE… Application WO-2017040813-A2 World Intellectual Property Organisation (WIPO) 09 Mar 2017
CRISPR-BASED GENOME MODIFICATION AND REGULATION Application EP-3138912-A1 European Patent Office 08 Mar 2017
Cas9-recombinase fusion proteins and uses thereof Grant US-9388430-B2 United States of America 12 Jul 2016
Engineered transcription activator-like effector (TALE) domains and uses thereof Grant US-9359599-B2 United States of America 07 Jun 2016
Evaluation and improvement of nuclease cleavage specificity Grant US-9322006-B2 United States of America 26 Apr 2016
Cas9-FokI fusion proteins and uses thereof Application US-9322037-B2 United States of America 26 Apr 2016
Methods for identifying a target site of a Cas9 nuclease Grant US-9163284-B2 United States of America 20 Oct 2015
PRECISE MICROBIOTA ENGINEERING AT THE CELLULAR LEVEL Application WO-2015069682-A3 World Intellectual Property Organisation (WIPO) 02 Jul 2015
Methods for correcting presenilin point mutations Application US-9068179-B1 United States of America 30 Jun 2015
CAS VARIANTS FOR GENE EDITING Application WO-2015089406-A1 World Intellectual Property Organisation (WIPO) 18 Jun 2015