RT @EvilArthurFleck: The risk haplotype 3p21.31 is linked to our Neanderthal DNA. The Denisovians of the mid-Paleolithic(early Asians) inte…
🤦🏻♂️🤦🏻♂️🤦🏻♂️ We've known that some diseases are prevalent in certain populations. (e.g. Tay-Sachs, Sickle cell ) . From 2021 https://t.co/hYwWXaOb2X 60% South Asians carry high-risk gene for COVID. THE #TRUTH IS #RACIST !! Congrats: #DOUBLESPEAK
@hsu_steve 4) Then there is the CambridgeU paper https://t.co/InVX8DGMEh "rs17713054G>A a probable causative variant .. arises from Neanderthal DNA .. confers over twofold increased risk of mortality .. carried by >60% with SAS ancestry, compared to
RT @dr_cottrell: Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus https://t.co/KAMS9bOIew
RT @dr_cottrell: Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus https://t.co/KAMS9bOIew
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus https://t.co/KAMS9bOIew
@NansTremouilles @LeSecond10 @LesbrosMarielle @DjooHeisenberg @kokacav @LaurentThines @HAS_sante @FrcsBraun @Elisabeth_Borne @EmmanuelMacron @Elysee @Cabinet_PM @gouvernementFR Gène LZTFL1 qui augmente très fortement les risques de décès en cas de Covid.
RT @EvilArthurFleck: @claushetting Yep. Sure. This scientist can answer this simple question with 3 tweets I did back in November 2021. Hap…
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…
RT @EvilArthurFleck: @claushetting Yep. Sure. This scientist can answer this simple question with 3 tweets I did back in November 2021. Hap…
@claushetting Yep. Sure. This scientist can answer this simple question with 3 tweets I did back in November 2021. Happy reading. 1. https://t.co/WnrdH6o51Z 2. https://t.co/k9bPoDWx1A 3. https://t.co/gTvLCmrxMx Thanks for the opportunity to answer this qu
@CiceroMD Yep. This scientist can answer that with 3 tweets I did back in November 2021. 1.https://t.co/WnrdH6o51Z 2. https://t.co/k9bPoDWx1A 3. https://t.co/gTvLCmrxMx
@dazugeberin @wie_jetzt @RWittenbrink Das Chromosom3p21.31 Haplotyp,Neandertaler-DNA,mit einer Verdoppelung des schweren COVID-Risk verbunden.Vmtl verantwortliche Genvariante👇betrifft auch Ostasiaten Chinesen,Japaner etc davon ausgeschlossen'reine'Afrikane
@darth_punjabi Whoever it is in the US that told you that you are 'immune', has deliberately lied to you, because they don't care about you. The reality is that people from South Asia are absolutely vulnerable to the virus and you should protect yourselves
RT @AltvaterUli: @QSehrose Scheint was dran zu sein: https://t.co/ZpW7CYT9dp
@QSehrose Scheint was dran zu sein: https://t.co/ZpW7CYT9dp
Trust the science… https://t.co/zm5cYbme1j
@beatesodeik @Stormageddon666 Konkret im Sinn hatte ich das hier aus UK mit LZTFL1: https://t.co/8Cyhz93zqn Bzw. das hier (inkl. TYK2), auch aus UK: https://t.co/IUXGwZJ1cU Aus DE sind mir solche Arbeiten bislang nicht bekannt.
@YodaBicycle @mfresow Einen Grund, warum uA in Asien immer noch etwas mehr Sorge vorherrscht, finden Sie in diesem Artikel: https://t.co/SIGZMYIlpl Wissenschaftlich: #1 https://t.co/ub0gneYpXq #2 https://t.co/aJNWppKUjx PS: freiwillig != vorgeschrieben
RT @mharisman: A single Neanderthal gene is likely to be responsible for up to a milln Covid deaths, an Oxford academic has claimed. The nu…
RT @mharisman: A single Neanderthal gene is likely to be responsible for up to a milln Covid deaths, an Oxford academic has claimed. The nu…
A single Neanderthal gene is likely to be responsible for up to a milln Covid deaths, an Oxford academic has claimed. The number of deaths globally from this genetic variant, which is found in 1 in 6 Britons, “is in the hundreds of thousands to a million”
Who has #Neanderthal DNA ? This is not great news for you. https://t.co/ozrwDprJMh
@PetziderBaer @kruevacanza @aosang @derspiegel Und hinzu kommt dann noch die Mutation von LZTFL1, die in Afrika nur 2 % haben, in Europa 15 % und in Indien 60 %. Das kann man zu Beginn einer Pandemie nicht wissen. https://t.co/dFAECJVv0k vgl. https://t.co/
"Selective spatial transcriptomic analysis of lung biopsies from patients with COVID-19 shows the presence of signals associated with epithelial–mesenchymal transition (EMT), a viral response pathway that is regulated by LZTFL1." https://t.co/8Cyhz93zqn
@phylogenomics Do you know if there is any evidence if this mutation also has any increased likelihood of Long Covid and also risk for kids with this mutation? This mutation causes 2x worse outcomes. https://t.co/ovsBwwVKkG
@AndrewDickson13 @AndrewLittleMP Here is the paper: https://t.co/ovsBwwVKkG.
RT @NatureGenet: 🌟OUT NOW @NatureGenet from @jojdavies @DownesDamien and @jrmmhughes 🔎Identification of LZTFL1 as a candidate effector gen…
RT @jojdavies: Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited…
RT @jojdavies: Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited…
RT @jojdavies: Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited…
RT @jojdavies: Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited…
RT @jojdavies: Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited…
Delighted to have teamed up with @sunderdown to discuss how the main gene we identified as causing severe Covid is inherited from Neanderthal. #CheltSciFest @cheltfestivals https://t.co/uqJ5ZEcv2D
RT @EricTopol: Early in the pandemic, the chromosome 3p21.31 locus (haplotype arising from Neanderthal DNA) was found to be associated with…
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus (Nature Genetics 14/11/21) covid-19 https://t.co/REUs1VyWHy
"LZTFL1, as a candidate causal gene potentially responsible 4 the twofold > risk of respiratory failure from C-19" >60% of ppl w South Asian ancestry carry this risk variant Another reason to work on strategic therapies, personalized risk assessme
“We conclude that pulmonary epithelial cells undergoing EMT, rather than immune cells, are likely responsible for the 3p21.31-associated risk. Since the 3p21.31 effect is conferred by a gain-of-function, LZTFL1 may represent a therapeutic target.” https://
Our next @ATS_GG journal club is tomorrow (25th Feb) @ 12ET! Feat “Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus” (https://t.co/RY1pDIkZjJ) Register @ https://t.co/1pFGda9wE9 @ATS_AII @ATS_Assemblies https://t.co/Onm9UNZ
Happening TOMORROW! Register now👇 https://t.co/xHhMhzCMgH
Our next @ATS_GG journal club is on the 25th Feb @ 12ET! Feat “Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus” (https://t.co/RY1pDIkZjJ) Register @ https://t.co/1pFGda9wE9 @ATS_AII @ATS_Assemblies https://t.co/MXthcM0lu2
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus https://t.co/RY1pDIkZjJ
leucine zipper transcription factor like 1 gain-of-function allele rs17713054G>A is involved in patients at higher risk of death from SARS2. I’m confident there will be many such findings to explain SARS2 risk: https://t.co/A8OwL6QgRI
Our next @ATS_GG journal club is on the 25th Feb @ 12ET! Feat “Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus” (https://t.co/RY1pDICAbh) Register @ https://t.co/1pFGdar7vH @ATS_AII @ATS_Assemblies https://t.co/2mKpCtpjly
Another work from former colleague (see pinned tweet). Not bad for the millionth pub from your post doc. Congrats Damien.
Por medio de GWAS, se identificó al gen LZTFL1, que ha sido poco estudiado, como causante de incrementar el riesgo de falla respiratoria por #COVID19 https://t.co/808NkybmMl
LZTFL1 gene #COVID https://t.co/Ce1pOGOUlD
RT @mttcrown: How did I miss this paper describing the gain-of-function SNP in LZTFL1, rs17713054G>A, as a probable causative variant to th…
How did I miss this paper describing the gain-of-function SNP in LZTFL1, rs17713054G>A, as a probable causative variant to the increased risk of respiratory failure due to COVID? #LZTFL1 #multiomics https://t.co/2jZIDrseBm
@RickABright @AC360 @CNN @SenSanders @CDCDirector @CDCgov LZTFL1 And Cilia. I think it's time anti vaxxers stop being Cilia and start getting serious. Also maybe this will point to the origin better in hedgehogs or something https://t.co/CvsoQ4kW7w
RT @GainOfDystopia: @Supernova_Style @MelpomeneMel @DecodingTrolls That was just one article. We can go into technical details. There ar…
@Supernova_Style @MelpomeneMel @DecodingTrolls That was just one article. We can go into technical details. There are harmful genes, and conversely protective ones: https://t.co/kvSmzYfJws
@DocBLaw Wonder if he/she has this gene: https://t.co/cxCFHAwj9O
@BarakRaveh @HovavDror פשטני מדי. לדוגמא https://t.co/Me6SANakde
[無料公開 | COVID-19特別翻訳記事] COVID-19リスク座位のエフェクター候補遺伝子として特定されたLZTFL1 Nature Genetics 2021年11月号 https://t.co/WPgSNXAtPL
RT @cctranslates: “I’m healthy/eat healthily/am young/got a strong immune system; I’ll be fine.” 15% of ppl of European & 60+% of S Asian…
RT @cctranslates: “I’m healthy/eat healthily/am young/got a strong immune system; I’ll be fine.” 15% of ppl of European & 60+% of S Asian…
“I’m healthy/eat healthily/am young/got a strong immune system; I’ll be fine.” 15% of ppl of European & 60+% of S Asian descent carry a gene that doubles risk of severe illness/death from COVID. How would you know? Vaccination greatly reduces this ri
RT @EricTopol: Early in the pandemic, the chromosome 3p21.31 locus (haplotype arising from Neanderthal DNA) was found to be associated with…
@nevercunninplan @Willmusic4food @PaulStenton1 @fascinatorfun There's also this: Bit more mind bending https://t.co/cE5aGJGaqz
RT @genotipia: Artículo original en: https://t.co/OKuOnWndIJ
Artículo original en: https://t.co/OKuOnWndIJ
Covid-19 risk locus! https://t.co/Oy4YZKb2EG
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus https://t.co/AA7sVoHj4L https://t.co/chfPxvxSMX
RT @BioDecoded: Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus | Nature Genetics https://t.co/5JWA2VLElr #…
RT @mharisman: "Two studies identified a region of chromosome 3p21.31 as having the strongest association, while a third study also identif…
"Two studies identified a region of chromosome 3p21.31 as having the strongest association, while a third study also identified this locus as conferring susceptibility to infection11. The 3p21.31 risk haplotype, which arises from Neanderthal DNA and is.."
Great paper from @jrmmhughes and @jojdavies @jdavieslab demonstrating the potential for using chromosome conformation capture (3C) analysis to identify the gene promotors in physical contact with a candidate enhancer sequence https://t.co/H8LUTASszy
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…
@PunkKia Absolutely nothing mysterious is going on its just basic genetics. https://t.co/0tqJvwk6TO
It didn't go unnoticed to me that very few people liked this thread explaining some science. But then I guess very few people actually understood it. And that, I guess, would explain why so many of you just did whatever your TV told you to do.
RT @EntropicEq: @pseudo_sapiens Apparantly ICMR's HoD Epidemiology isn't exactly epidemiolog-ing!!! n = ~4200 & the usual prelim/needs fur…
@pseudo_sapiens Apparantly ICMR's HoD Epidemiology isn't exactly epidemiolog-ing!!! n = ~4200 & the usual prelim/needs further work disclaimer applies... https://t.co/5VTZfEedFS
RT @BioDecoded: Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus | Nature Genetics https://t.co/5JWA2VLElr #…
RT @TNYBN123: Er is een gen gevonden dat ervoor zorgt dat de kans dat je aan Covid-19 overlijdt verdubbelt. Het gen, LZTFL1, wordt gedragen…
RT @TNYBN123: Er is een gen gevonden dat ervoor zorgt dat de kans dat je aan Covid-19 overlijdt verdubbelt. Het gen, LZTFL1, wordt gedragen…
Er is een gen gevonden dat ervoor zorgt dat de kans dat je aan Covid-19 overlijdt verdubbelt. Het gen, LZTFL1, wordt gedragen door 60% van de mensen van Zuid-Aziatische afkomst en 15% van de mensen van Europese afkomst. https://t.co/LKUJEFh8rx https://t
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus | Nature Genetics https://t.co/7ufwKZHbA4
@TheChai_vinist @Paulanasenya @DottaAtoti @oleturana waambiwe!
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…
RT @EvilArthurFleck: The risk haplotype 3p21.31 is linked to our Neanderthal DNA. The Denisovians of the mid-Paleolithic(early Asians) inte…
The risk haplotype 3p21.31 is linked to our Neanderthal DNA. The Denisovians of the mid-Paleolithic(early Asians) interbred with them. Homosapiens moving into Europe in the late-Paleolithic raped them to extinction. Those that stayed on the African contine
RT @EvilArthurFleck: Here's one for us real science nerds. Having the genetic risk haplotype 3p21.31 raises your risk of catching Covid &…