NEURONAL TRANSFECTION METHOD BASED ON ADIPOSE-DERIVED EXOSOMES AND USE THEREOF Application WO-2024050923-A1 World Intellectual Property Organisation (WIPO) 14 Mar 2024
miRNA biogenesis in exosomes for diagnosis and therapy Grant US-11926824-B2 United States of America 12 Mar 2024
Edible plant-derived microvesicle compositions for diagnosis and treatment of disease Grant US-11890382-B2 United States of America 06 Feb 2024
Extracellular vesicles and methods of using Grant US-11883434-B2 United States of America 30 Jan 2024
Method and device for high field strength electrotransfection of microvescicles and cells Grant US-11878300-B2 United States of America 23 Jan 2024
Extracellular vesicles and methods and uses thereof Grant US-11717480-B2 United States of America 08 Aug 2023
Vesicles comprising a PTEN inhibitor and uses of same Grant US-11648260-B2 United States of America 16 May 2023
Anti-C9ORF72 oligonucleotides and related methods Grant US-11629347-B2 United States of America 18 Apr 2023
PLASMID PLATFORM FOR STABLE EXPRESSION AND DELIVERY OF BIOMOLECULES Application WO-2023038479-A1 World Intellectual Property Organisation (WIPO) 16 Mar 2023
SMALL EXTRACELLULAR VESICLES EXPRESSING A DOMINANT NEGATIVE AMPK ALPHA 1 MUTANT FOR USE… Application EP-4137148-A1 European Patent Office 22 Feb 2023
Compositions for facilitating membrane fusion and uses thereof Grant US-11576872-B2 United States of America 14 Feb 2023
SMALL EXTRACELLULAR VESICLES EXPRESSING A DOMINANT NEGATIVE AMPK ALPHA 1 MUTANT FOR USE… Application WO-2023012076-A1 World Intellectual Property Organisation (WIPO) 09 Feb 2023
Endogenous Gag-based capsids and uses thereof Grant US-11505578-B2 United States of America 22 Nov 2022
Exosomal loading using hydrophobically modified oligonucleotides Grant US-11505807-B2 United States of America 22 Nov 2022
Gene editing methods and compositions for eliminating risk of JC virus activation and PML … Grant US-11491207-B2 United States of America 08 Nov 2022
EXTRACELLULAR VESICLES FROM MESENCHYMAL STROMAL CELLS FOR TREATMENT OF DISEASES Application WO-2022223767-A1 World Intellectual Property Organisation (WIPO) 27 Oct 2022
Compositions and methods relating to myomaker-induced muscle cell fusion Grant US-11471509-B2 United States of America 18 Oct 2022
NUCLEIC ACID DELIVERY SYSTEM AND APPLICATION THEREOF Application WO-2022206788-A1 World Intellectual Property Organisation (WIPO) 06 Oct 2022
Endogenous Gag-based capsids and uses thereof Grant US-11447527-B2 United States of America 20 Sep 2022
Composition for delivery of genetic material Grant US-11230715-B2 United States of America 25 Jan 2022
EXTRACELLULAR VESICLES FOR TREATING NEUROLOGICAL DISORDERS Application WO-2021184017-A1 World Intellectual Property Organisation (WIPO) 16 Sep 2021
PRODUCTS FOR SUPPRESSING OR REDUCING THE EXPRESSION OR ACTIVITY OF A SNORNA AND USES… Application WO-2021175966-A1 World Intellectual Property Organisation (WIPO) 10 Sep 2021
NEUROSOME/ASTROSOME COMPOSITIONS AND METHODS OF USE Application WO-2021091582-A1 World Intellectual Property Organisation (WIPO) 14 May 2021
EXOSOMES FOR TARGET SPECIFIC DELIVERY AND METHODS FOR PREPARING AND DELIVERING THE SAME Application EP-3668552-A4 European Patent Office 28 Apr 2021
Use of exosomes for the treatment of disease Grant US-10959952-B2 United States of America 30 Mar 2021
METHODS, SYSTEMS, AND COMPOSITIONS FOR CELL-DERIVED/VESICLE-BASED MICRORNA DELIVERY Grant EP-3336190-B1 European Patent Office 24 Feb 2021
OLIGONUCLEOTIDE COMPOUNDS FOR TARGETING HUNTINGTIN MRNA Application EP-3766973-A1 European Patent Office 20 Jan 2021
Compositions and methods thereof for down-regulation of genes following oral delivery of… Grant US-10889825-B2 United States of America 12 Jan 2021
Extracellular vesicle-based diagnostics and engineered exosomes for targeted therapeutics… Grant US-10874610-B2 United States of America 29 Dec 2020
Therapeutic immune modulation by stem cell secreted exosomes Grant US-10869916-B2 United States of America 22 Dec 2020
Exosomal compositions and methods for the treatment of disease Grant US-10799457-B2 United States of America 13 Oct 2020
Exosomes for target-specific delivery and methods for making and delivering the same Application CN-111629761-A China 04 Sep 2020
TELOMERASE-CONTAINING EXOSOMES FOR TREATMENT OF DISEASES ASSOCIATED WITH AGING AND AGE-RELA… Application WO-2020163705-A1 World Intellectual Property Organisation (WIPO) 13 Aug 2020
Isolation of extracellular vesicles (EVs) from red blood cells for gene therapy Grant US-10709797-B2 United States of America 14 Jul 2020
Composition for delivery of genetic material Grant US-10704047-B2 United States of America 07 Jul 2020
Recombinant protein-based method for the delivery of silencer RNA to target the brain Grant US-10640539-B2 United States of America 05 May 2020
Targeted extracellular vesicles comprising membrane proteins with engineered… Grant US-10624849-B2 United States of America 21 Apr 2020
Targeted and modular exosome loading system Grant US-10538570-B2 United States of America 21 Jan 2020
VESICLES FOR TRACELESS DELIVERY OF GUIDE RNA MOLECULES AND/OR GUIDE RNA MOLECULE/RNA-GUIDED… Application WO-2020012335-A1 World Intellectual Property Organisation (WIPO) 16 Jan 2020
Exosomal loading using hydrophobically modified oligonucleotides Application US-10513710-B2 United States of America 24 Dec 2019
ENGINEERING EXTRACELLULAR VESICLES FOR AFFINITY PURIFICATION Application WO-2019238626-A1 World Intellectual Property Organisation (WIPO) 19 Dec 2019
CELL-TYPE SPECIFIC EXOSOMES AND USE THEREOF Application WO-2019198077-A1 World Intellectual Property Organisation (WIPO) 17 Oct 2019
MIRNA BIOGENESIS IN EXOSOMES FOR DIAGNOSIS AND THERAPY Application EP-3527670-A1 European Patent Office 21 Aug 2019
Composition for delivery of genetic material Grant US-10329561-B2 United States of America 25 Jun 2019
Methods, systems, and compositions relating to MiRNA-146a Application US-10308959-B2 United States of America 04 Jun 2019
Composition for delivery of genetic material Grant US-10233445-B2 United States of America 19 Mar 2019
Methods, systems, and compositions for cell-derived/vesicle-based microRNA delivery Application US-10227593-B2 United States of America 12 Mar 2019
Recombinant protein-based method for the delivery of silencer RNA to target the brain Application US-10208098-B2 United States of America 19 Feb 2019
COMPOSITIONS FOR FACILITATING MEMBRANE FUSION AND USES THEREOF Application WO-2018208728-A1 World Intellectual Property Organisation (WIPO) 15 Nov 2018
Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases Grant US-10100308-B2 United States of America 16 Oct 2018
EXTRACELLULAR VESICLE-BASED DIAGNOSTICS AND ENGINEERED EXOSOMES FOR TARGETED THERAPEUTICS… Application WO-2018075825-A1 World Intellectual Property Organisation (WIPO) 26 Apr 2018
COMPOSITIONS CONTAINING PROTEIN LOADED EXOSOME AND METHODS FOR PREPARING AND DELIVERING… Application WO-2018062973-A1 World Intellectual Property Organisation (WIPO) 05 Apr 2018
AN IN VITRO METHOD FOR OBTAINING A BIOHYBRID VECTOR Application EP-3292861-A1 European Patent Office 14 Mar 2018
Methods and compositions for the packaging of nucleic acids into microglial exosomes for… Application US-9840542-B2 United States of America 12 Dec 2017
METHODS, SYSTEMS, AND COMPOSITIONS FOR CELL-DERIVED/VESICLE-BASED MICRORNA DELIVERY Grant EP-2791336-B1 European Patent Office 29 Nov 2017
Esosomi ingegnerizzati per il trattamento della leucemia mieloide cronica Application IT-UA20162620-A1 Italy 15 Oct 2017
3-D COLLAGEN SCAFFOLD-GENERATED EXOSOMES AND USES THEREOF Application WO-2017152035-A1 World Intellectual Property Organisation (WIPO) 08 Sep 2017
Compositions and methods for diagnosing autism Grant US-9752192-B2 United States of America 05 Sep 2017
EXOSOMES FOR DELIVERY OF BIOTHERAPEUTICS Application EP-3192526-A3 European Patent Office 30 Aug 2017
EXOSOME PACKAGING OF NUCLEIC ACIDS Application WO-2017054085-A1 World Intellectual Property Organisation (WIPO) 06 Apr 2017
USE OF EXOSOMES FOR THE TREATMENT OF DISEASE Application WO-2016201323-A1 World Intellectual Property Organisation (WIPO) 15 Dec 2016
MICROVESICLE, AND MANUFACTURING METHOD FOR SAME Application EP-2975125-A4 European Patent Office 26 Oct 2016
Therapeutic immune modulation by stem cell secreted exosomes Grant US-9427450-B2 United States of America 30 Aug 2016
Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases Grant US-9388414-B2 United States of America 12 Jul 2016
Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases Grant US-9388413-B2 United States of America 12 Jul 2016
NANOVESICULAR THERAPIES Application WO-2016077639-A3 World Intellectual Property Organisation (WIPO) 30 Jun 2016
Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease Grant US-9149492-B2 United States of America 06 Oct 2015
Retrograde transport peptide and use of same for delivery to central nervous system Grant US-9056892-B2 United States of America 16 Jun 2015
MICROPARTICLES, MIRNA AND WOUND THERAPY Application WO-2015052527-A1 World Intellectual Property Organisation (WIPO) 16 Apr 2015
THERAPEUTIC DELIVERY VESICLES Application WO-2014168548-A3 World Intellectual Property Organisation (WIPO) 04 Dec 2014
MIRNA BIOGENESIS IN EXOSOMES FOR DIAGNOSIS AND THERAPY Application WO-2014152622-A1 World Intellectual Property Organisation (WIPO) 25 Sep 2014
BRAIN-TARGETING FUNCTIONAL NUCLEIC ACID AND USE THEREOF Application EP-2702999-A4 European Patent Office 17 Sep 2014
COMPOSITION AND DELIVERY VEHICLE FOR ACTIVE AGENTS AND METHODS THEREFOR Application WO-2014057043-A1 World Intellectual Property Organisation (WIPO) 17 Apr 2014
BRAIN-TARGETING FUNCTIONAL NUCLEIC ACID AND USE THEREOF Application EP-2702999-A1 European Patent Office 05 Mar 2014
EXOSOME-BASED THERAPEUTICS AGAINST NEURODEGENERATIVE DISORDERS Application WO-2014028763-A1 World Intellectual Property Organisation (WIPO) 20 Feb 2014
COMBINATION FOR TREATING AN INFLAMMATORY DISORDER Application WO-2014003553-A1 World Intellectual Property Organisation (WIPO) 03 Jan 2014
In vivo delivery of double stranded RNA to a target cell Grant US-8524679-B2 United States of America 03 Sep 2013