RT @ShorterLab: Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in precl…
Variant-selective stereopure #oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models $WVE $IONS $PRQR $BPTH $NBSE $RHHBY #antisense #gapmer #ASO @jwattsgroup @HastingsLab @Mendell_lab @AntisenseL http
RT @NatureComms: C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonuc…
RT @NatureComms: C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonuc…
このG4C2リピートに限らずショートリピートによる神経変性を治療できる未来が来るかも。 オリゴはフォスフォジエステル結合じゃなくてPSで繋がってて、スプライシングマシナリに保護されてないリピートを認識してRNase Hで分解させるって感じ。
RT @NatureComms: C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonuc…
RT @NatureComms: C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonuc…
RT @NatureComms: C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonuc…
C9orf72 expansion mutations are the most common genetic cause of #ALS and #FTD. @WaveLifeSci generated stereopure oligonucleotides depleting expansion-containing transcripts and protecting motor #neurons. https://t.co/6eBcVS8sm6
New article: Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models. https://t.co/Qbj3xFGlO9 #MS #multiplesclerosis #neurology https://t.co/itr95Iksu0
RT @ShorterLab: Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in precl…
RT @ShorterLab: Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in precl…
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72 -repeat expansion in preclinical models | Nature Communications https://t.co/XOI8xIdR6z
RT @ShorterLab: Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in precl…
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models: https://t.co/Sg5dGZc4OX
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models https://t.co/bnnLxTem0w
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models https://t.co/qvXA3Jv528
Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models - Nature - ALS via BrainSights for iOS https://t.co/suCuKujZH3