Title |
Obesity-related metabolic dysfunction in dogs: a comparison with human metabolic syndrome
|
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Published in |
BMC Veterinary Research, August 2012
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DOI | 10.1186/1746-6148-8-147 |
Pubmed ID | |
Authors |
Asta Tvarijonaviciute, Jose J Ceron, Shelley L Holden, Daniel J Cuthbertson, Vincent Biourge, Penelope J Morris, Alexander J German |
Abstract |
Recently, metabolic syndrome (MS) has gained attention in human metabolic medicine given its associations with development of type 2 diabetes mellitus and cardiovascular disease. Canine obesity is associated with the development of insulin resistance, dyslipidaemia, and mild hypertension, but the authors are not aware of any existing studies examining the existence or prevalence of MS in obese dogs.Thirty-five obese dogs were assessed before and after weight loss (median percentage loss 29%, range 10-44%). The diagnostic criteria of the International Diabetes Federation were modified in order to define canine obesity-related metabolic dysfunction (ORMD), which included a measure of adiposity (using a 9-point body condition score [BCS]), systolic blood pressure, fasting plasma cholesterol, plasma triglyceride, and fasting plasma glucose. By way of comparison, total body fat mass was measured by dual-energy X-ray absorptiometry, whilst total adiponectin, fasting insulin, and high-sensitivity C-reactive protein (hsCRP) were measured using validated assays. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 33% |
United States | 1 | 33% |
United Kingdom | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 2 | <1% |
Denmark | 1 | <1% |
Unknown | 203 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 30 | 15% |
Student > Master | 24 | 12% |
Student > Doctoral Student | 22 | 11% |
Researcher | 21 | 10% |
Other | 20 | 10% |
Other | 52 | 25% |
Unknown | 37 | 18% |
Readers by discipline | Count | As % |
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Veterinary Science and Veterinary Medicine | 70 | 34% |
Medicine and Dentistry | 38 | 18% |
Agricultural and Biological Sciences | 28 | 14% |
Biochemistry, Genetics and Molecular Biology | 9 | 4% |
Nursing and Health Professions | 4 | 2% |
Other | 19 | 9% |
Unknown | 38 | 18% |