Bet.
Interesting method from Rodrigues et al "To introduce timestamps, we tag RNA with a reporter motif consisting of multiple MS2 binding sites that recruit the adenosine deaminase ADAR2 fused to an MS2 capsid protein" https://t.co/AA7ehVkKZK
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
By exploiting RNA editing, @SGRodriques et al developed "RNA timestamps", a method for inferring the age of individual RNAs in RNA-seq data https://t.co/DbztlYT7Gm
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @markwbudde: Very cool: engineering A->I in RNA can encode mRNA age. I once saw global polyA shortening after blocking transcription, an…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @nobolly: RNA timestamps identify the age of single molecules in RNA sequencing | Nat Biotech https://t.co/xEAsPQg3bm A-to-I edits by a…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @nobolly: RNA timestamps identify the age of single molecules in RNA sequencing | Nat Biotech https://t.co/xEAsPQg3bm A-to-I edits by a…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
interesting
RT @daweonline: RNA timestamps identify the age of single molecules in RNA sequencing | Nature Biotechnology https://t.co/PuAAEiLDRh
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @daweonline: RNA timestamps identify the age of single molecules in RNA sequencing | Nature Biotechnology https://t.co/PuAAEiLDRh
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
Very cool: engineering A->I in RNA can encode mRNA age. I once saw global polyA shortening after blocking transcription, and learned that polyA length shortens with time. Measuring the polyA tail length should achieve something similar, without engineer
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
Really cool advancement on scRNAseq 😁!
Pretty clever approach for clocking mRNA age by tagging it with an A to I editor, so that As gradually turn to Is.
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @daweonline: RNA timestamps identify the age of single molecules in RNA sequencing | Nature Biotechnology https://t.co/PuAAEiLDRh
RT @daweonline: RNA timestamps identify the age of single molecules in RNA sequencing | Nature Biotechnology https://t.co/PuAAEiLDRh
Very cool paper- RNA timestamps enable temporal analysis of gene expression, in single cells!
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @raflynn5: Using ADAR to repeatedly edit RNAs, allowing for the tracking of their "age" from Fei Chen @eboyden3 @HSCRB @broadinstitute…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @coregenomics: A seriously cool modification to #rnaseq that means you can see when individual promoters were active. The method is beau…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RNAの年齢(転写からの経過時間)を見積もるツール。 標的RNAにMS2結合配列を付けておいて、MS2に融合したアデノシンデアミナーゼを発現させれば、時間経過とともに標的RNA上でA to I(イノシン)の編集が蓄積するので、そこから見積りが可能 https://t.co/ngg4LdmPrM
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @coregenomics: A seriously cool modification to #rnaseq that means you can see when individual promoters were active. The method is beau…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @raflynn5: Using ADAR to repeatedly edit RNAs, allowing for the tracking of their "age" from Fei Chen @eboyden3 @HSCRB @broadinstitute…
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @raflynn5: Using ADAR to repeatedly edit RNAs, allowing for the tracking of their "age" from Fei Chen @eboyden3 @HSCRB @broadinstitute…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RNA timestamps identify the age of single molecules in RNA sequencing | Nature Biotechnology https://t.co/PuAAEiLDRh
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @xgraubove: «ADAR2 binding to tagged RNA causes A-to-I edits to accumulate over time, allowing the age of the RNA to be inferred **with…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @xgraubove: «ADAR2 binding to tagged RNA causes A-to-I edits to accumulate over time, allowing the age of the RNA to be inferred **with…
«ADAR2 binding to tagged RNA causes A-to-I edits to accumulate over time, allowing the age of the RNA to be inferred **with hour-scale accuracy**.» This is outrageously futuristic.
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @markowetzlab: The beginning of the end of pseudo-time algorithms https://t.co/Ov4WAxd53D
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
My god the possibilities! I was just thinking the other day I needed a good general “science is cool” moment. Here it is!
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @SGRodriques: New paper out today in @NatureBiotech with Linlin Chen, Fei Chen, @eboyden3, and many other wonderful coauthors, demonstra…
RT @coregenomics: A seriously cool modification to #rnaseq that means you can see when individual promoters were active. The method is beau…
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @NatureBiotech: RNA timestamps identify the age of single molecules in RNA sequencing https://t.co/5r00Hrpnyc https://t.co/ozsPFcHkAz
RT @VY_stem: Slowly but surely going from Pseudotime predictions, to real time observations using single cell RNA-seq! 👏 https://t.co/Hre0h…