@kidneydoc101 @TYoungstein @RichardHaynes3 @lastwalsh @GileadSciences Besides, plex has been suggested for covid. Just don't plex off the rituxan or remdesvir if you give those. https://t.co/68IbtMWwW8
Would plasmapheresis be worth trying among COVID-19 patients as well? An argument for the therapy: https://t.co/C1WIKQ9bYM
RT @PDKcritcare: It is diff than the convalescent transfusion but still with risks and a bit more labor intensive. It involves removal of p…
It is diff than the convalescent transfusion but still with risks and a bit more labor intensive. It involves removal of patient plasma and replacement with healthy donor. Some data in sepsis with mods and this is group that needs to be investigated- covid
RT @PDKcritcare: Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulati…
RT @PDKcritcare: Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulati…
RT @PDKcritcare: Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulati…
RT @PDKcritcare: Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulati…
RT @PDKcritcare: Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulati…
Definitely need to investigate this further. Mounting evidence/reports of inflammation and clotting- even on anticoagulation. #plex #TPE #COVIDー19 #sepsis #StrongerTogether #strongwork
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19. https://t.co/31xmZHVzp8 https://t.co/QDXHY1uL5R
@shyonekm @MorganEdde @TheRightMelissa @realDonaldTrump @BretBaier As well as plasmapheresis. https://t.co/c8yW5umZNE
This treatment theoretically should help treat the endotheliopathy and microcirculatory clotting demonstrates on autopsy. Any recommendation on systemic anticoagulation for these patients with markedly elevated ddimer? #COVID #COVIDー19 #CoronavirusUSA #ple
RT @DrAlexConcorde: @jopo899 .dralex: There's been quite a lot about this (& of course its multi-facetted just to make it more difficult) e…
@jopo899 .dralex: There's been quite a lot about this (& of course its multi-facetted just to make it more difficult) eg https://t.co/PW3rxqdrpP and https://t.co/T5JNXgUs4y and https://t.co/05PhMegVSA There's also the direct effects on RBCs...
This is a promising therapy that, in theory, treats the endotheliopathy and microclotting common to sepsis that we believe leads to organ failure and death. Needs more investigation. #plex #COVIDー19 #coronavirus #plasmapheresis #ARDS #sepsis #TPE #strongwo
https://t.co/JWiGtpE0Et @Maha_MEDD @mybmc @MoHFW_INDIA @ICMRDELHI Have you seen this ?
Resultados: En el subgrupo de pacientes que presentaron neumonía como fuente primaria de infección se vio una marcada disminución de mortalidad (47.8% vs 81.3%, p=0.05). Free full text https://t.co/oTgFWorLTj
RT @PDKcritcare: We have used in a handful of cases of sepsis with multiple organ dysfunction due to covid and have had very promising resu…
RT @Jaybgone: https://t.co/KXtFIouyAW Anyone getting calls for this yet?
https://t.co/KXtFIouyAW Anyone getting calls for this yet?
RT @PDKcritcare: Offers theoretical benefit by treating downstream effects of viral activation, potentially reversing the downstream effect…
Offers theoretical benefit by treating downstream effects of viral activation, potentially reversing the downstream effects. Needs further investigation ASAP. #COVID2019 #plex #plasmapheresis #ARDS #sepsis #strongwork
Certainly promising therapy that needs further investigation. By treating cytokine and endothelium along with microangiopathy could potentially reverse organ failure while awaiting viral clearance. #COVID2019 https://t.co/4HXXrZjRAj
Role of PLASMAPHRESIS in COVID!!! #COVID2019 https://t.co/rbETRzqlWu
RT @ProfMakris: Interesting proposal to use plasma exchange in the sick intensive care patients with COVID-19. I believe it is definitely w…
@arorasatyam12 @docrahulkats @RajbirCheema4
RT @ProfMakris: Interesting proposal to use plasma exchange in the sick intensive care patients with COVID-19. I believe it is definitely w…
RT @ProfMakris: Interesting proposal to use plasma exchange in the sick intensive care patients with COVID-19. I believe it is definitely w…
RT @ProfMakris: Interesting proposal to use plasma exchange in the sick intensive care patients with COVID-19. I believe it is definitely w…
This could also go with the finding of aps antibodies... maybe some similarities with CAPS physiopathology?
Interesting proposal to use plasma exchange in the sick intensive care patients with COVID-19. I believe it is definitely worth exploring, but only as part of a clinical trial as the procedure uses a lot of fresh frozen plasma. https://t.co/yx3ckYtnmt
@csentropy Here is a great treatment that has potential for unbelievable outcomes during the COID epidemic. @PDKcritcare https://t.co/v3nxKGTxgZ
This is a cool idea!!
Definite trend that seems to be associated with mortality and pathologic findings on autopsies. Both macro and micro clots. Seems anticoagulation needed but also ? role of tpe to assist reversing to endothelial activation of microcirculation. https://t.co/
Very encouraging and needs further exploration. Cytokines huge part but endothelial activation and microclots need to be addressed as well. #plex #plasmapheresis #Covid_19 #ARDS #sepsis @HarmonyFaithDPT @ingridmmn
the medical establishment is catching on: “A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19” https://t.co/LtbeReyEfE
RT @RobertLKruse: Been thinking about this as a treatment option for #COVID19. Need more data to confirm immune complex formation beyond hy…
Been thinking about this as a treatment option for #COVID19. Need more data to confirm immune complex formation beyond hypothesis but timing of anti-spike antibody formation is interesting. That said, antibodies in convalescent plasma seem to help. May hav
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @PDKcritcare: @HarmonyFaithDPT @kossler323 we have to treat the pathologic process that leads to organ failure while the virus is active…
Treating the microthrombosis May allow for organ stabilization and decrease recovery time, decreasing morbidity and preserving resources. #plex #tpe #Covid_19 #COVIDー19 #coronavirus #ARDS #sepsis #strongwork
RT @PDKcritcare: Treating the downstream effects of the virus, hopefully reversing the organ ischemia and failure. #COVIDー19 #TPE #plex #AR…
RT @ElieBalesh: With all of this in mind, plasmapheresis (a.k.a. therapeutic plasma exchange) to filter out pathogenic immune complexes fro…
RT @juliovacacelaMD: Revisión bibliográfica publicada por médicos del Lexington Medical Center🇺🇸 sobre el uso del plasma de pacientes que s…
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 https://t.co/6tQzJ3aVJJ #foamed
@HarmonyFaithDPT @kossler323 we have to treat the pathologic process that leads to organ failure while the virus is active. #COVID19 #plex #TPE #plasmapheresis #ARDS #sepsis #strongwork
Treating the downstream effects of the virus, hopefully reversing the organ ischemia and failure. #COVIDー19 #TPE #plex #ARDS #sepsis #plasmapheresis #strongwork
Efectos de la plasmaféresis: -Remoción de citoquinas inflamatorias -Estabilización de la membrana endotelial -Remisión del estado hipercoagulable https://t.co/ZW7znA7aG1 #MQC #COVIDー19 #hematology
@abtahi_parvaneh @NephRodby https://t.co/NKGHXgDHST. Published by our critical care colleagues here in Columbia (i’m not advocating for it for the record).
@AmandaJaneWilde @sthembete @DrZweliMkhize @nicd_sa @HealthZA @sindivanzyl Thank you. I see where your coming from and your passion. Here is the evidence I read: https://t.co/xQkuBm0HZm In selected patients it may be considered. However, in KZN, limiting f
@Lenin @ottosonnenh @Salud_Ec @PedroPabloDuart
RT @PDKcritcare: Cautiously hopeful this may help save lives and resources. Plasma donors readily available and cheaper than ventilators an…
Cautiously hopeful this may help save lives and resources. Plasma donors readily available and cheaper than ventilators and icu beds if the clinical response is what we hope. #COVIDー19 #coronavirus #plex #tpe #strongwork #ARDS #sepsis
Revisión bibliográfica publicada por médicos del Lexington Medical Center🇺🇸 sobre el uso del plasma de pacientes que superaron el COVID-19 como tratamiento para casos fulminantes. Indican que la terapia “se muestra prometedora” y proponen se investigue. h
We need to explore this promising therapy. Net result on resources could be favorable if indeed clinically efficacious. ?Less vents and less icu beds? #covid #coronavirus #plex #tpe @PDKcritcare #strongwork #ards #sepsis
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
I am not a pathologist, just bedside clinician. However, the endothelial induced microangiopathy has low level hemolysis, may not be detected on manual smear. Clinical surrogates of LDH and ddimer May guide treatment. TPE offering promise https://t.co/4HXX
https://t.co/4HXXrZjRAj plasma exchange may treat the downstream effects that are what leads to organ failure and death. Treating and containing this pathway seems like the necessary medicine. Needs full volume exchange with plasma. @ @PDKcritcare @Crit_Ca
@wittykidney @kmadass @NephRodby Of course #plex might help but not practical at scale. @TYoungstein signposted me to this study #COVID19 2/ https://t.co/gcIumSqVKM
RT @juliovacacela: Revisión bibliográfica realizada por médicos del Lexington Medical Center🇺🇸 sobre el uso del plasma de pacientes que sup…
RT @juliovacacela: Revisión bibliográfica realizada por médicos del Lexington Medical Center🇺🇸 sobre el uso del plasma de pacientes que sup…
Revisión bibliográfica realizada por médicos del Lexington Medical Center🇺🇸 sobre el uso del plasma de pacientes que superaron el COVID-19 como tratamiento para casos fulminantes. Indican que la terapia “se muestra prometedora” y proponen se investigue.
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
We need to explore this. Targeting a single component is unlikely to work. PLEX attacks on multiple levels. @PDKcritcare @SCCM @Crit_Care @emcrit #COVID19Pandemic #sepsis #ARDS #plex #plasma4coronavirus #plasmaexchange #strongwork
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
RT @Crit_Care: #CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment…
#CritCare #OpenAccess https://t.co/HL173hJUWz #COVID19 & global health Is therapeutic #PlasmaExchange a promise treatment of the systemic response? #FOAMed #FOAMcc #BMC #IntensiveCare #pandemics #coronavirus #infection #inflammation #cytokine #co
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant #COVID19 @Crit_Care | #ECM https://t.co/FOMVslQI43
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant #COVID19 @Crit_Care | #ECM https://t.co/ccce2e7iZb
Important info- please take into consideration with treatment of #Covid_19
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 https://t.co/5zqetmEH19 #covid19ase
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 https://t.co/5zqetmEH19 #covid19ase #feedly
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant #COVID19 | Critical Care | Full Text https://t.co/p7KFFfplEh
Plasma Transfusion is already a reality, DAMN! https://t.co/Rsc3xXtAB1
RT @PDKcritcare: COVID sets likely sets off the same cascade common so sepsis and other shock states. #TPE #plex might offer hope. If we ca…
COVID sets likely sets off the same cascade common so sepsis and other shock states. #TPE #plex might offer hope. If we can catch it early maybe we can avoid the morbidity and resource demand. #COVID19 #COVID19Pandemic #strongwork #ARDS #sepsis https://t.c
Interesting read.... A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulfiminant COVID-19 https://t.co/DlbpmwO2HC
RT @JanHartmannMD: A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminan…
A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 Via @Crit_Care https://t.co/VTT696NAKd