RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
The future of actual CAR-T cells?
RT @nresearchnews: A @NatImmunol paper describes a new type of killer T-cell that could lead to a universal cancer therapy. The findings sh…
Exciting discovery in @NatImmunol, advancing our knowledge about the immune system and for the possibility of new medicines. A T-cell that finds MR1 in cancer cells; MR1 is flagging the distorted intracellular cancer metabolism to the immune system https
RT @zakkohane: Big deal POSSIBLE future cancer therapy: Beautiful result from CRISPR-Cas9 screen: MR1-targeted (MHC class I protein) T cell…
Crispr-cas9 screening revealed a TCR that recognizes class I like molecule MR1 & can kill many tumor cells types independent of class I. Is an HLA-independent pan-cancer immunotherapy using a MR1-specific TCR on the horizon? What does it recognize? htt
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @cowcreekgeek: @Alpha_57 This is real; this is a likely answer... https://t.co/FYtMG8wtzl
Study ($): Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 https://t.co/PJ3ctUvAgL #TCellReceptor #TCellReceptors #immunotherapy
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @EricTopol: Discovery of a T cell receptor clone (via genome-wide #CRISPR) with the potential of pan-#cancer, pan-population immunothera…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @IlanYLevine: @LibertyJen In fact, there were two potentially huge discoveries made this week: 1) Special T-cells which attack tumors…
RT @ingentium_mel: #genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell #cancer targeting via the monomorphic MHC class I-related p…
#genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell #cancer targeting via the monomorphic MHC class I-related protein MR1. https://t.co/bBqBu1A7ma
RT @IlanYLevine: @LibertyJen In fact, there were two potentially huge discoveries made this week: 1) Special T-cells which attack tumors…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
@LibertyJen In fact, there were two potentially huge discoveries made this week: 1) Special T-cells which attack tumors but not healthy cells https://t.co/Tbll9RMp2Q… & 2) Novel way to fight glioblastomas by enlisting immune system where it is not no
@Alpha_57 This is real; this is a likely answer... https://t.co/FYtMG8wtzl
New @NatImmunol paper: "These findings offer opportunities for HLA-independent, pan-cancer, pan-population immunotherapies". https://t.co/htMg9jbw2F
RT @ScienceCrisp: Genome-wide #CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related pro…
Genome-wide #CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Crowther MD [..] Sewell AK. Nat Immunol. 2020-01-20. https://t.co/9YzVffyGkO
RT @Kabe5rock: これは本当に凄い。市場が動くぞ https://t.co/tMacQ2bFJa
So excited about this finding!
@LluisMontoliu Otro éxito CRISPR-Cas9 https://t.co/Z3GOMyAQXB
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
Great advance in #immunology! #CRISPR #genomics https://t.co/CmP5NgTb55
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
Wow...
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
@KUMA_Tweet_2019 因みに、この論文。https://t.co/a6az24DVHl
https://t.co/NkzxwMNucC A new type of immune cell was discovered that could be used to kill most cancers. During lab tests, the T-cells were able to kill lung, skin, blood, colon, breast, bone, prostate, ovarian, kidney and cervical cancer cells, while not
RT @SarahJReports: Immune discovery 'may treat all cancer' https://t.co/hsxdPazGWo https://t.co/Z9QJEJ3YbN
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 | Nature Immunology https://t.co/EkPYwmeZBN
#Genome-wide #CRISPR–Cas9 screening reveals ubiquitous T cell #cancer targeting via the monomorphic MHC class I-related protein MR1 | Nature Immunology https://t.co/JtBMNRaw2q
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
これは本当に凄い。市場が動くぞ https://t.co/tMacQ2bFJa
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @EricTopol: Discovery of a T cell receptor clone (via genome-wide #CRISPR) with the potential of pan-#cancer, pan-population immunothera…
This could be big!
21k accesses in 2 days 🤯 @TcellResearch https://t.co/FI5KOwRhMe
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @FilippoMontemu1: Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related p…
Potential for HLA-independent pan-cancer immunotherapy using a MR1-specific TCR. #GAMBiT_2020 https://t.co/kt4gHBkD6z
RT @ARampotas: Universal CAR-Ts against a universal cancer antigen. This is huge ! Can t wait to see how it develops https://t.co/5hj971gwba
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 | Nature Immunology https://t.co/z8bJKmg8Hf
@JSheltzer Seems like the recent M1R paper suggests that some metabolic determinants may exist. Even if we don't know what they are yet. The paper describes a tumor-specific TCR that seems to recognize some (presumably metabolic) ligand being presented by
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC (potential for pan-cancer, pan-population CAR-T) https://t.co/fUauvPGPTy
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @zakkohane: Big deal POSSIBLE future cancer therapy: Beautiful result from CRISPR-Cas9 screen: MR1-targeted (MHC class I protein) T cell…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
Makale önemli. Bu immünoterapi sayesinde tüm kanser türlerinin iyileştirilebileceği söyleniyor. https://t.co/WZFWX1l6jC Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1 http
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
Trending on PubMed: Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. https://t.co/bHJ9TKxLsk
@eduardogade Tente este link:https://t.co/Il9e3hhwfu
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
Amazing breakthrough!
Small step for man, potentially a giant leap for mankind towards the treatment of #Cancer. Excellent paper👌 Also, a wonderful summary in the link below: https://t.co/pgIQCyeaSE
RT @YaleMichaels: This T cell receptor appears to be able to target dozens of different cancer types while ignoring healthy tissues.. but w…
RT @TcellResearch: Here's the link to that new paper, published today in Nature Immunology. https://t.co/sV65aofo8m
New @NatImmunol article gives insight to an HLA-independent #cancer treatment using T cell therapy recognizing a MHC class-1 protein MR1 (that does not vary amongst humans). It might be a treatment to help all patients suffering various #cancer types. h
Universal CAR-Ts against a universal cancer antigen. This is huge ! Can t wait to see how it develops
Very interesting paper suggesting MR1 as a pan-cancer target, while remaining inert to noncancerous cells. Removing one of the biggest disadvantages of immunotherapy!
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
RT @NatImmunol: Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted…
Sewell and colleagues show nonclassical MHC molecule MR1 is expressed on a wide variety of cancer types and can be targeted by conventional T cells.https://t.co/OEX9Uqb8fk https://t.co/2W8XA12k2C
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
HLA-indept, pan-cancer, pan-patient. Too good to be true? Hopefully not 🙏🏻 https://t.co/zGaqi9WLHe
@prayingmedic Thinking its this ref: https://t.co/BBQDxfRr1W interesting. should await phase I-III trial results.
RT @EricTopol: Discovery of a T cell receptor clone (via genome-wide #CRISPR) with the potential of pan-#cancer, pan-population immunothera…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @EricTopol: Discovery of a T cell receptor clone (via genome-wide #CRISPR) with the potential of pan-#cancer, pan-population immunothera…
Cancer cured! https://t.co/hLBnXlcxp2
RT @Labome: Genome-wide CRISPR–Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…
RT @davidasinclair: Wow! Immune cells found to target a cancer-ubiquitous protein called MR1 that recognizes vitamin B2 derivatives. Could…