| Title |
High-sensitivity intravascular photoacoustic imaging of lipid–laden plaque with a collinear catheter design
|
|---|---|
| Published in |
Scientific Reports, April 2016
|
| DOI | 10.1038/srep25236 |
| Pubmed ID | |
| Authors |
Yingchun Cao, Jie Hui, Ayeeshik Kole, Pu Wang, Qianhuan Yu, Weibiao Chen, Michael Sturek, Ji-Xin Cheng |
| Abstract |
A highly sensitive catheter probe is critical to catheter-based intravascular photoacoustic imaging. Here, we present a photoacoustic catheter probe design on the basis of collinear alignment of the incident optical wave and the photoacoustically generated sound wave within a miniature catheter housing for the first time. Such collinear catheter design with an outer diameter of 1.6 mm provided highly efficient overlap between optical and acoustic waves over an imaging depth of >6 mm in D2O medium. Intravascular photoacoustic imaging of lipid-laden atherosclerotic plaque and perivascular fat was demonstrated, where a lab-built 500 Hz optical parametric oscillator outputting nanosecond optical pulses at a wavelength of 1.7 μm was used for overtone excitation of C-H bonds. In addition to intravascular imaging, the presented catheter design will benefit other photoacoustic applications such as needle-based intramuscular imaging. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 25% |
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 74 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 14 | 19% |
| Researcher | 11 | 15% |
| Student > Doctoral Student | 7 | 9% |
| Student > Bachelor | 7 | 9% |
| Other | 7 | 9% |
| Other | 12 | 16% |
| Unknown | 16 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 26 | 35% |
| Physics and Astronomy | 12 | 16% |
| Medicine and Dentistry | 8 | 11% |
| Chemistry | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Other | 3 | 4% |
| Unknown | 16 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 166. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2020.
All research outputs
#205,015
of 22,869,263 outputs
Outputs from Scientific Reports
#2,395
of 123,517 outputs
Outputs of similar age
#4,268
of 299,124 outputs
Outputs of similar age from Scientific Reports
#69
of 3,150 outputs
Altmetric has tracked 22,869,263 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
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