@matthewshaw1111 This goes for conventional drugs, too. Remember that ADR- Adverse Drug Reactions- are the 6th to 4th leading cause of death. Not faulty or error or misdosed- those are called ADE- Adverse Dug Events. Drug trials are designed to mask the d
“Adverse events account for more than 100,000 deaths per year in the United States1, representing the 4th leading cause of death, after heart disease, cancer and stroke, but well ahead of diabetes, pulmonary diseases and AIDS.” https://t.co/Wm1XcYX8Ry
【併用による副作用データベース】 FAERSを用いている。化合物名はRxNormでnormalize。AEに対して登録されている化合物のペアについて寄与率を計算。尤度比検定を行う。validationはシクロスポリンに着目。 https://t.co/72wGIOoCb0
Database of adverse events associated with drugs and drug combinations https://t.co/bo6acVzbA5
Database of adverse events associated with drugs and drug combinations https://t.co/GXwicohGjX #nor論文 複数の薬剤の組み合わせで出るASについての解析。色んな情報を使った色んな解析が出て、使える情報や解析法がもっと出てきて欲しい