RT @biogerontology: That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out…
RT @biogerontology: That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out…
RT @biogerontology: That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out…
RT @biogerontology: That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out…
RT @biogerontology: That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out…
That was one epic moment I remember in generative AI for drug discovery. Got some criticism back then. And now, ten out of 20 pharma companies are using our software. And generative platform is used in agriculture, materials, even on clean energy @EricTopo
@ylecun Don't forget this one. Now, it is everywhere https://t.co/cyafxr1ZK5
RT @organischchemie: インシリコメディシンの論文あったなーと思ったらもう四年も前か https://t.co/iHiMGmOG8A これはDDR1阻害剤 この論文でもめっちゃ短い期間で薬が作れるって言ってた気がする
インシリコメディシンの論文あったなーと思ったらもう四年も前か https://t.co/iHiMGmOG8A これはDDR1阻害剤 この論文でもめっちゃ短い期間で薬が作れるって言ってた気がする
A 2019 paper in Nature Biotechnology reported the use of AI in the discovery of inhibitors of DDR1, a kinase which has been implicated in fibrosis. Many may have noticed that Compound 1 in https://t.co/MwXXTLFYny bears a striking resemblance to Pontatinib
@EricTopol, founder of the Scripps Research Translational Institute, said AI has already shown a lot of promise in reducing the time and cost of drug development, even though regulators had not yet approved a drug entirely developed using the technology ht
RT @Next_Gadgets: Artificial intelligence is rapidly advancing. It can now design novel druglike molecules in 46 days instead of years. htt…
RT @BRAINCURES: GENTRL was used to discover potent inhibitors of DDR1, a kinase target implicated in fibrosis and other diseases, in 21 day…
GENTRL was used to discover potent inhibitors of DDR1, a kinase target implicated in fibrosis and other diseases, in 21 days. 4 compounds were active in biochemical assays, & 2 were validated in cell-based assays. One lead candidate demonstrated favora
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
is this the sort of thing Thisby was talking about? @Natashatashaetc
@itamblyn I think this paper may be close to what you’re describing. The authors synthesize a few of the molecules proposed by a generative model. It’s been a couple years since I’ve read the paper so I could be mistaken. https://t.co/Fje55ou1mF
@andrewwhite01 This paper comes to mind regarding deep learning @biogerontology @InSilicoMeds https://t.co/njly7StbZg
@biogerontology et al used GENTRL to discover potent inhibitors of DDR1, in 21 days. 4 compounds were active in biochemical assays, and 2 were validated in cell-based assays. One lead candidate was tested and demonstrated favorable pharmacokinetics in mice
RT @Chemistry_Net: Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #De…
RT @Chemistry_Net: Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #De…
RT @Chemistry_Net: Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #De…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #DeepLearning https://t.co/xdeiUm13tL
RT @Chemistry_Net: Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #De…
RT @Chemistry_Net: Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #De…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors #chemistry #biochemistry #Bioinformatics #DeepLearning https://t.co/xdeiUm13tL
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
Read more about GENTRL here https://t.co/MlGQZ5yEco
RT @StefanoBerto83: @tangming2005 Here one example of drug discovery prediction I remember reading time ago. https://t.co/xjNwMP1C8U
RT @StefanoBerto83: @tangming2005 Here one example of drug discovery prediction I remember reading time ago. https://t.co/xjNwMP1C8U
@tangming2005 Here one example of drug discovery prediction I remember reading time ago. https://t.co/xjNwMP1C8U
The topic sounded familiar. Indeed it is: "Deep-learning enables rapid identification of potent DDR1 kinase inhibitors" by Alex Zhavoronkov, published in 2019. Not cited by the authors of the new paper. An impressive oversight by authors & referees (2/
@MaartenvSmeden It's work from @InSilicoMeds and went from discovering kinase inhibitors, that got tested in cell lines and mice - so at least a full workflow and not only theoretical: https://t.co/4ZXDd0PhQj
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
@MartinBJensen @LNuzhna @WillManidis @Dereklowe Regarding the much-lauded 2019 paper in Nature Biotechnology where they synthesized a lead (https://t.co/wglklBbDVK) , it was pointed out the drug was very similar to one in the training data: https://t.co/V
@DerekLowe, great article on considerations of AI drug candidate screenings https://t.co/xnEx1ntlmK What're your thoughts on using multi objective models to balance candidate optimisation (https://t.co/ta1hwJeSTm) against toxicity?
@suneel_bvs Two studies leap to mind: https://t.co/iDe8A6KS8z and https://t.co/fGv9LPfAiI (but see also and https://t.co/r6JTRgkync and https://t.co/UDLb31FauO)
@andrewgwils This depends on how you define strong empirical results, but I'd say that generative models have been fairly successful in computational chemistry (both academia and industry), see e.g. startups like Insilico Medicine, Generate Biomedicines an
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @olexandr: @jakeith01 @ProfvLilienfeld @PeONor This is a book chapter about #compchem: https://t.co/wPZ1pAGjR7 and also recent high prof…
RT @olexandr: @jakeith01 @ProfvLilienfeld @PeONor This is a book chapter about #compchem: https://t.co/wPZ1pAGjR7 and also recent high prof…
RT @olexandr: @jakeith01 @ProfvLilienfeld @PeONor This is a book chapter about #compchem: https://t.co/wPZ1pAGjR7 and also recent high prof…
RT @olexandr: @jakeith01 @ProfvLilienfeld @PeONor This is a book chapter about #compchem: https://t.co/wPZ1pAGjR7 and also recent high prof…
@jakeith01 @ProfvLilienfeld @PeONor This is a book chapter about #compchem: https://t.co/wPZ1pAGjR7 and also recent high profile paper about ML “suggesting” new compounds: https://t.co/pl0m2qGKfa
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
Recent preclinical de novo drug discovery successes based on AI, admittedly not yet FDA approved. 1. DDR1 kinase inhibitors https://t.co/YjOaUJsKA3 2. Antibiotics https://t.co/6NdW78d45R
RT @kaifulee: Fully agree, @EricTopol. AI drug discovery in 46 days! Very encouraging to see the AI empowered breakthrough by our newly add…
RT @kaifulee: Fully agree, @EricTopol. AI drug discovery in 46 days! Very encouraging to see the AI empowered breakthrough by our newly add…
RT @kaifulee: Fully agree, @EricTopol. AI drug discovery in 46 days! Very encouraging to see the AI empowered breakthrough by our newly add…
ZANIMLJIVOSTI MOLEKULARNE 2019: Primenom veštačke inteligencije je dizajnirano šest novih inhibitora proteina kinaze DDR1 koja je uključena u fibrozu i druge bolesti. . https://t.co/WdEQvi60v7 . https://t.co/IicTrv36tx T: +381 11 3975744 [email protected]@imgge.bg.ac.r">[email protected]>
RT @alycemayfosh: Papers like this get me so excited! So I'm starting a group for #researchers to share & discuss new #technologies in rese…
RT @alycemayfosh: Papers like this get me so excited! So I'm starting a group for #researchers to share & discuss new #technologies in rese…
Papers like this get me so excited! So I'm starting a group for #researchers to share & discuss new #technologies in research. Think #MachineLearning, #AI & #QuantumComputing. Open to students, E/M/SrCRs & entrepreneurs. You interested? #Academ
RT @lamethodeFC: [#Etude] 02/09/2019 > Le #DeepLearning et son implication dans la découverte d’un potentiel médicament contre la #fibrose…
RT @lamethodeFC: [#Etude] 02/09/2019 > Le #DeepLearning et son implication dans la découverte d’un potentiel médicament contre la #fibrose…
[#Etude] 02/09/2019 > Le #DeepLearning et son implication dans la découverte d’un potentiel médicament contre la #fibrose https://t.co/2ovyb4Tm3V via @NatureBiotech #LaMethSci
RT @kylejnorton: @Deloitte published a report on AI-powered drug discovery culminating with AI discovering a drug-like molecule in 46 days.…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @AndreEsteva: GAN-based RL discovers drug candidate for fibrosis in 21 days. Proves to be favorable in mice. 1) Encoder: chemical space…
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @machinelearnflx: Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRl…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @machinelearnflx: Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRl…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @machinelearnflx: Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRl…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @cnancyxu: There are a lot of minds in #AI for #DrugDiscovery nowadays, and it finally looks like we’re making progress. Designed, valid…
@jeremyphoward A similar one, used to find molecules to fight some cancers: https://t.co/1Vk16l1DGQ
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
RT @EricTopol: There's been a lot of buzz about #AI for drug discovery. But I think this is the best case yet: All in 46 days! https://t.co…
Now aexample of catalyzing drug development efforts previous.... https://t.co/V2ivPXjIES
RT @machinelearnflx: Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRl…
Deep learning enables rapid identification of potent DDR1 kinase inhibitors | Nature Biotechnology https://t.co/JMyaRlO52S #DeepLearning #Iot
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @EricTopol: Now a 3rd example of #AI catalyzing drug development efforts. Previous @InSilicoMeds @NatureBiotech https://t.co/O6pwmnrX3K…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
RT @EricTopol: Now a 3rd example of #AI catalyzing drug development efforts. Previous @InSilicoMeds @NatureBiotech https://t.co/O6pwmnrX3K…
RT @NatureBiotech: #Deeplearning enables rapid identification of potent DDR1 kinase inhibitors https://t.co/9hyDYFCm7f https://t.co/sNBZDZm…
AI for drug design is here !