Scientists reveal DNA packaging mechanism of HSV-1, the virus that causes cold sores
Biospace,
UCLA team’s results could lead to ways to improve antiviral therapy A new technique developed by researchers from the…
UCLA team’s results could lead to ways to improve antiviral therapy A new technique developed by researchers from the…
A new technique developed by researchers from the California NanoSystems Institute at UCLA has allowed them to become the first…
3-D cryo-electron microscopy reconstruction of the HSV-1 portal vertex, where DNA (red) is pumped into the viral shell.
编辑推荐: 这项研究展示了疱症病毒完整的非对称结构,获得了第一个真核生物病毒的DNA通道原子模型,也是第一次探测到DNA在通道里的扭曲状态。审稿人评论说,“作者采用最前沿的局部分类方法对疱疹病毒结构的完美解析,堪称高分辨冷冻电镜三维重建的匠心力作。” 疱疹病…
5月30日, 《自然》杂志在线发表了中国科学技术大学合肥微尺度物质科学国家研究中心、生命科学学院博士刘云涛、教授毕国强与合作者的研究论文,该工作利用冷冻电镜首次解析了人类疱疹病毒基因组包装的关键机制以及病毒的 DNA 基因组结构,有助于预防和控制疱疹病毒引发…