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Case report: severe asymptomatic hyponatremia in Prader-Willi Syndrome

Overview of attention for article published in BMC Pediatrics, February 2016
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Title
Case report: severe asymptomatic hyponatremia in Prader-Willi Syndrome
Published in
BMC Pediatrics, February 2016
DOI 10.1186/s12887-016-0563-4
Pubmed ID
Authors

Daniel Landau, Harry J. Hirsch, Varda Gross-Tsur

Abstract

Prader-Willi syndrome is a complex neurogenetic, multisystem disorder. Despite the variable endocrine abnormalities and hypothalamic-pituitary axis dysfunction, hyponatremia has been reported in only a few PWS patients. In previously reported PWS individuals, hyponatremia was associated with abnormal fluid intake or during desmopressin treatment. We describe an infant with Prader-Willi syndrome who had severe, prolonged asymptomatic hyponatremia without a history of excessive fluid intake or desmopressin treatment. We compare the findings with those of the few other reported cases and describe, for the first time, results of a hypertonic saline infusion test and studies of adrenal cortical function. Hyponatremia should be suspected in children with Prader-Willi syndrome, especially in infants with severe failure to thrive. Further studies are needed to determine the pathophysiology of hyponatremia in this syndrome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 27%
Other 2 18%
Student > Bachelor 2 18%
Student > Ph. D. Student 2 18%
Lecturer 1 9%
Other 0 0%
Unknown 1 9%
Readers by discipline Count As %
Medicine and Dentistry 5 45%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Agricultural and Biological Sciences 1 9%
Nursing and Health Professions 1 9%
Unknown 3 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2016.
All research outputs
#20,310,658
of 22,851,489 outputs
Outputs from BMC Pediatrics
#2,596
of 3,007 outputs
Outputs of similar age
#251,807
of 298,014 outputs
Outputs of similar age from BMC Pediatrics
#27
of 29 outputs
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