RT @SperlingMD: Patient genotyping may predict response to 3 out of 4 FDA-approved #alzheimers drugs that increase a neurotransmitter invol…
Patient genotyping may predict response to 3 out of 4 FDA-approved #alzheimers drugs that increase a neurotransmitter involved in learning and memory. https://t.co/w4Mt4wrgxu
iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context. https://t.co/sZur6H3frI
iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context (Trans Pysch) https://t.co/tQ35078JwL https://t.co/tQ35078JwL
iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context. https://t.co/omfqJY2ita
iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context. https://t.co/sZur6H3frI #Neuralstemcells
融合遺伝子CHRFAM7Aが多いと、PNU調整α7ニコチン性アセチルコリン受容体電流脱感作が強まる。CHRFAM7AはAβ1–42取り込みの用量反応を緩和する。CHRFAM7AがあるとAβ1–42取り込みでニューロンのIL-1βやTNF-αが活性化するが、標準的インフラマソーム経路は活性化するとはいえない https://t.co/Q39tqYM6Pg
iPSC model of CHRFAM7A effect on α7 nicotinic acetylcholine receptor function in the human context @buffalostate #InducedPluripotent #StemCells https://t.co/sFHmD8FM8v https://t.co/alC2VHFczm