| Title |
The psychological impact of genetic information on children: a systematic review
|
|---|---|
| Published in |
Genetics in Medicine, January 2016
|
| DOI | 10.1038/gim.2015.181 |
| Pubmed ID | |
| Authors |
Claire E. Wakefield, Lucy V. Hanlon, Katherine M. Tucker, Andrea F. Patenaude, Christina Signorelli, Jordana K. McLoone, Richard J. Cohn |
| Abstract |
This review assessed the psychological impact that acquiring personal and familial genetic information has on children. We also examined the concordance between the available empirical data and clinical guidance/perspectives articles. We screened 591 abstracts and identified 13 studies, representing 966 children. Ten studies assessed 386 children tested for familial adenomatous polyposis (n = 171), hereditary cardiac disease (n = 134), and other conditions (n = 81). Three studies addressed the impact of BRCA1/2 testing of a family member on 580 children. Serious adverse psychological outcomes were uncommon. Most studies reported no significant increase in mean anxiety, depression, and distress scores (n = 8, 61.5%); however, some children experienced intrafamilial distress, discrimination, and guilt/regret. Some children were more concerned about their own health or their family members' health. There was limited consistency between anticipated adverse impact and empirical data. The review identified little conclusive evidence of deleterious psychological consequences for children acquiring genetic information. However, there is a lack of data regarding genetic testing for conditions that may not be treatable/modifiable, as well as a dearth of longitudinal studies. Therefore, clinical caution remains essential for the ethical integration of genetic testing into pediatrics. Further research assessing the potential positive and negative effects of genetic testing in childhood is warranted.Genet Med advance online publication 07 January 2016Genetics in Medicine (2015); doi:10.1038/gim.2015.181. |
X Demographics
The data shown below were collected from the profiles of 78 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 21 | 27% |
| Australia | 8 | 10% |
| United Kingdom | 3 | 4% |
| Spain | 2 | 3% |
| Canada | 2 | 3% |
| Lebanon | 1 | 1% |
| Germany | 1 | 1% |
| Côte d'Ivoire | 1 | 1% |
| South Africa | 1 | 1% |
| Other | 3 | 4% |
| Unknown | 35 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 48 | 62% |
| Scientists | 22 | 28% |
| Practitioners (doctors, other healthcare professionals) | 5 | 6% |
| Science communicators (journalists, bloggers, editors) | 3 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 140 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 139 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 29 | 21% |
| Student > Bachelor | 22 | 16% |
| Researcher | 18 | 13% |
| Other | 10 | 7% |
| Student > Doctoral Student | 9 | 6% |
| Other | 25 | 18% |
| Unknown | 27 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 18% |
| Medicine and Dentistry | 25 | 18% |
| Psychology | 21 | 15% |
| Agricultural and Biological Sciences | 11 | 8% |
| Nursing and Health Professions | 8 | 6% |
| Other | 16 | 11% |
| Unknown | 34 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2023.
All research outputs
#719,050
of 25,658,541 outputs
Outputs from Genetics in Medicine
#188
of 2,956 outputs
Outputs of similar age
#12,404
of 401,671 outputs
Outputs of similar age from Genetics in Medicine
#2
of 59 outputs
Altmetric has tracked 25,658,541 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,956 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.0. This one has done particularly well, scoring higher than 93% of its peers.
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We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.