| Title |
Three-dimensional non-destructive soft-tissue visualization with X-ray staining micro-tomography
|
|---|---|
| Published in |
Scientific Reports, September 2015
|
| DOI | 10.1038/srep14088 |
| Pubmed ID | |
| Authors |
Juliana Martins de S. e Silva, Irene Zanette, Peter B. Noël, Mateus B. Cardoso, Melanie A. Kimm, Franz Pfeiffer |
| Abstract |
Low inherent contrast in soft tissues has been limiting the use of X-ray absorption micro-computed tomography (micro-CT) to access high-resolution structural information of animal organs. The staining agents used in micro-CT to improve the contrast fail in providing high-quality images of whole organs of animals due to diffusion problems of the staining agent into the sample. We demonstrate a staining protocol that incorporates a biochemical conditioning step prior to exposure to the staining agent that succeeds in overcoming the diffusion problems, thus quickly providing high-quality micro-CT images of whole organs of mammals. Besides of yielding non-distorted three-dimensional information at the same spatial resolution accessible in histological sections, micro-CT images of whole organs stained by our method enable easy screening of slices along any direction of the volume thus demonstrating new possibilities of structural analysis in biomedical science. |
Mendeley readers
The data shown below were compiled from readership statistics for 162 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| Unknown | 160 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 37 | 23% |
| Student > Ph. D. Student | 34 | 21% |
| Student > Bachelor | 26 | 16% |
| Student > Master | 23 | 14% |
| Student > Doctoral Student | 11 | 7% |
| Other | 10 | 6% |
| Unknown | 21 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 26 | 16% |
| Medicine and Dentistry | 25 | 15% |
| Agricultural and Biological Sciences | 17 | 10% |
| Physics and Astronomy | 17 | 10% |
| Biochemistry, Genetics and Molecular Biology | 13 | 8% |
| Other | 31 | 19% |
| Unknown | 33 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2018.
All research outputs
#2,943,474
of 22,829,083 outputs
Outputs from Scientific Reports
#25,277
of 123,250 outputs
Outputs of similar age
#41,992
of 274,965 outputs
Outputs of similar age from Scientific Reports
#441
of 2,234 outputs
Altmetric has tracked 22,829,083 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 123,250 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,965 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 2,234 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.