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Clinical outcomes in Caucasian patients with polypoidal choroidal vasculopathy

Overview of attention for article published in Eye, July 2018
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Mentioned by

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3 tweeters

Citations

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4 Dimensions

Readers on

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13 Mendeley
Title
Clinical outcomes in Caucasian patients with polypoidal choroidal vasculopathy
Published in
Eye, July 2018
DOI 10.1038/s41433-018-0168-2
Pubmed ID
Authors

Eleftherios I. Agorogiannis, Ian A. Pearce, Sohraab Yadav, David G. Parry, Nicholas A. V. Beare

Abstract

To describe treatment outcomes in a cohort of Caucasian patients with polypoidal choroidal vasculopathy (PCV). Clinical charts from 48 eyes of 45 Caucasian patients with PCV were retrospectively reviewed. All cases were diagnosed with indocyanine green angiography. Best corrected visual acuity (BCVA) and optical coherence tomography (OCT) imaging were analyzed at baseline and final follow-up. Eyes were treated with a combination of verteporfin photodynamic therapy (PDT) and anti-vascular endothelial growth factor (VEGF) (n = 24), or PDT monotherapy (n = 9), or anti-VEGF monotherapy (n = 8), or no treatment (n = 7). Aflibercept was the anti-VEGF agent in 30 out of 32 eyes. Sixteen out of 24 eyes in the combination treatment group received initial PDT at diagnosis. All treatments led to stabilization of BCVA at final visit with a trend for better visual acuity in the anti-VEGF monotherapy group. There was a substantial reduction in central retinal thickness associated with resolution of subfoveal fluid and improvement in retinal pigment epithelial detachment in all treatment groups. BCVA and OCT findings remained stable in eyes which received no treatment. The use of PDT was associated with 0.5 fewer intravitreal injections per annum, which was not statistically significant. In the largest series of Caucasian patients with PCV presented to date, anti-VEGF monotherapy, PDT, or their combination preserved visual acuity and improved subfoveal exudative changes. Combination treatment was not superior to anti-VEGF monotherapy.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 23%
Student > Bachelor 2 15%
Other 2 15%
Student > Ph. D. Student 1 8%
Unknown 5 38%
Readers by discipline Count As %
Medicine and Dentistry 4 31%
Nursing and Health Professions 2 15%
Materials Science 1 8%
Agricultural and Biological Sciences 1 8%
Unknown 5 38%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2019.
All research outputs
#11,252,883
of 18,865,206 outputs
Outputs from Eye
#1,626
of 3,567 outputs
Outputs of similar age
#148,153
of 286,892 outputs
Outputs of similar age from Eye
#27
of 72 outputs
Altmetric has tracked 18,865,206 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,567 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,892 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.