The evolution, evolvability and engineering of gene regulatory DNA
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Abstract Mutations in non-coding regulatory DNA sequences can alter gene expression, organismal phenotype and fitness1,2,3.
Abstract Mutations in non-coding regulatory DNA sequences can alter gene expression, organismal phenotype and fitness1,2,3.
Abstract DNA can determine where and when genes are expressed, but the full set of sequence determinants that control gene…
A new tool called DeepBind uses deep learning to analyze how proteins bind to DNA and RNA, allowing it to detect mutations that…
The binding specificities of RNA and DNAbinding proteins are determined from experimental data using a deep learning approach.
A new tool called DeepBind uses deep learning to analyze how proteins bind to DNA and RNA, allowing it to detect mutations that…