Compositions and methods for transient delivery of nucleases Grant US-11920168-B2 United States of America 05 Mar 2024
Recombinant adeno-associated viruses for delivering gene editing molecules to embryonic… Grant US-11882815-B2 United States of America 30 Jan 2024
Methods of treating amyotrophic lateral sclerosis (ALS) Grant US-11859179-B2 United States of America 02 Jan 2024
Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization Grant US-11851657-B2 United States of America 26 Dec 2023
Method to enhance the efficiency of systemic AAV gene delivery to the central nervous… Grant US-11826433-B2 United States of America 28 Nov 2023
Compositions and methods for modulating dysferlin expression Grant US-11827886-B2 United States of America 28 Nov 2023
RAAV-based compositions and methods for treating amyotrophic lateral sclerosis Grant US-11760999-B2 United States of America 19 Sep 2023
SOD1 dual expression vectors and uses thereof Grant US-11739330-B2 United States of America 29 Aug 2023
Method of increasing the function of an AAV vector Grant US-11680274-B2 United States of America 20 Jun 2023
Adeno-associated virus capsid variants and methods of use thereof Grant US-11680249-B2 United States of America 20 Jun 2023
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-11565001-B2 United States of America 31 Jan 2023
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-11565000-B2 United States of America 31 Jan 2023
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-11554180-B2 United States of America 17 Jan 2023
Prostate-targeting adeno-associated virus serotype vectors Grant US-11426469-B2 United States of America 30 Aug 2022
AAV-based treatment of cholesterol-related disorders Grant US-11421230-B2 United States of America 23 Aug 2022
Methods and compositions for treating metabolic imbalance Grant US-11413356-B2 United States of America 16 Aug 2022
REDUCING CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS Application US-20220098613-A1 United States of America 31 Mar 2022
Methods and compositions for treating metabolic imbalance in neurodegenerative disease Grant US-11253576-B2 United States of America 22 Feb 2022
Compositions and methods for enhanced gene expression in cone cells Grant US-11248214-B2 United States of America 15 Feb 2022
Adeno-associated virus virions with variant capsid Grant US-11236402-B2 United States of America 01 Feb 2022
Compositions and methods for selective inhibition of grainyhead-like protein expression Grant US-11207426-B2 United States of America 28 Dec 2021
Adeno-associated virus variants and methods of use thereof Grant US-11136557-B2 United States of America 05 Oct 2021
Anti-angiogenic miRNA therapeutics for inhibiting corneal neovascularization Grant US-11060088-B2 United States of America 13 Jul 2021
Compositions and methods for intravitreal delivery of polynucleotides to retinal cones Grant US-11021519-B2 United States of America 01 Jun 2021
Heterologous targeting peptide grafted AAVS Grant US-11014976-B2 United States of America 25 May 2021
Assays for the detection of AAV neutralizing antibodies Grant US-10983110-B2 United States of America 20 Apr 2021
Recombinant AAV vectors useful for reducing immunity against transgene products Grant US-10975391-B2 United States of America 13 Apr 2021
RAAV-based compositions and methods for treating amyotrophic lateral sclerosis Grant US-10954518-B2 United States of America 23 Mar 2021
Method of increasing the function of an AAV vector Grant US-10947561-B2 United States of America 16 Mar 2021
Recombinant AAVS having useful transcytosis properties Grant US-10894949-B2 United States of America 19 Jan 2021
Adeno-associated virus variants and methods of use thereof Grant US-10883117-B2 United States of America 05 Jan 2021
RAAV-based compositions and methods for treating amyotrophic lateral sclerosis Grant US-10851375-B2 United States of America 01 Dec 2020
CNS targeting AAV vectors and methods of use thereof Grant US-10731178-B2 United States of America 04 Aug 2020
AAV-based treatment of cholesterol-related disorders Grant US-10731158-B2 United States of America 04 Aug 2020
RAAV-based compositions and methods for treating amyotrophic lateral sclerosis Grant US-10711274-B2 United States of America 14 Jul 2020
High efficiency library-identified AAV vectors Grant US-10711270-B2 United States of America 14 Jul 2020
Compositions and methods for modulating dysferlin expression Grant US-10689653-B2 United States of America 23 Jun 2020
Compositions and methods for transient delivery of nucleases Grant US-10584321-B2 United States of America 10 Mar 2020
Adeno-associated virus virions with variant capsid and methods of use thereof Application US-10494612-B2 United States of America 03 Dec 2019
Heterologous targeting peptide grafted AAVS Grant US-10370432-B2 United States of America 06 Aug 2019
RAAV-based compositions and methods for treating amyotrophic lateral sclerosis Grant US-10280418-B2 United States of America 07 May 2019
Mutant adeno-associated virus virions and methods of use thereof Application US-10214566-B2 United States of America 26 Feb 2019
Adeno-associated virus virions with variant capsid and methods of use thereof Application US-10214785-B2 United States of America 26 Feb 2019
AAV-based treatment of cholesterol-related disorders Grant US-10202600-B2 United States of America 12 Feb 2019
Adeno-associated virus virions with variant capsid and methods of use thereof Application US-10202657-B2 United States of America 12 Feb 2019
Recombinant AAVS having useful transcytosis properties Grant US-10072251-B2 United States of America 11 Sep 2018
Mutant adeno-associated virus virions and methods of use thereof Grant US-10046016-B2 United States of America 14 Aug 2018
RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies Grant US-9885057-B2 United States of America 06 Feb 2018
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-9856539-B2 United States of America 02 Jan 2018
CNS targeting AAV vectors and methods of use thereof Grant US-9701984-B2 United States of America 11 Jul 2017
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-9587282-B2 United States of America 07 Mar 2017
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-9458517-B2 United States of America 04 Oct 2016
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-9457103-B2 United States of America 04 Oct 2016
Mutant adeno-associated virus virions and methods of use thereof Application US-9441244-B2 United States of America 13 Sep 2016
AAV-based treatment of cholesterol-related disorders Grant US-9272053-B2 United States of America 01 Mar 2016
Mutant adeno-associated virus virions and methods of use thereof Application US-9233131-B2 United States of America 12 Jan 2016
Adeno-associated virus virions with variant capsid and methods of use thereof Grant US-9193956-B2 United States of America 24 Nov 2015
CNS targeting AAV vectors and methods of use thereof Grant US-9102949-B2 United States of America 11 Aug 2015
Multiple promoter expression cassettes for simultaneous delivery of RNAi agents Grant US-8691967-B2 United States of America 08 Apr 2014
Multiple promoter expression cassettes for simultaneous delivery of RNAi agents Grant US-8283461-B2 United States of America 09 Oct 2012
RNAi expression constructs with liver-specific enhancer/promoter Grant US-8008468-B2 United States of America 30 Aug 2011
Multiple promoter expression cassettes for simultaneous delivery of RNAi agents targeted… Application US-7727970-B2 United States of America 01 Jun 2010