Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

RT @KimrynRathmell: Day 5 #RCCAwareness Building on the discovery of VHL mutation came the finding of a major transcription hub--disregulat…

RT @KimrynRathmell: Day 5 #RCCAwareness Building on the discovery of VHL mutation came the finding of a major transcription hub--disregulat…

And a mere 20 years later we figured out how to make HIF a druggable target..

RT @KimrynRathmell: Day 5 #RCCAwareness Building on the discovery of VHL mutation came the finding of a major transcription hub--disregulat…

Day 5 #RCCAwareness Building on the discovery of VHL mutation came the finding of a major transcription hub--disregulated Hypoxia Inducible Factors (HIF1 and HIF2) https://t.co/cGOOmFBzfQ driving VEGF and GLUT1 expression in #RCC without hypoxia. #Pseudoh