| Title |
Attolitre-sized lipid bilayer chamber array for rapid detection of single transporters
|
|---|---|
| Published in |
Scientific Reports, June 2015
|
| DOI | 10.1038/srep11025 |
| Pubmed ID | |
| Authors |
Naoki Soga, Rikiya Watanabe, Hiroyuki Noji |
| Abstract |
We present an attolitre-sized arrayed lipid bilayer chamber system (aL-ALBiC) for rapid and massively parallel single-molecule assay of membrane transporter activity. Because of the small reaction volume (200 aL), the aL-ALBiC performed fast detection of single transporter activity, thereby enhancing the sensitivity, throughput, and accuracy of the analysis. Thus, aL-ALBiC broadens the opportunities for single-molecule analysis of various membrane transporters and can be used in pharmaceutical applications such as drug screening. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 86 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 31% |
| Researcher | 15 | 17% |
| Student > Postgraduate | 7 | 8% |
| Student > Master | 7 | 8% |
| Student > Bachelor | 6 | 7% |
| Other | 13 | 15% |
| Unknown | 13 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 17 | 19% |
| Biochemistry, Genetics and Molecular Biology | 13 | 15% |
| Agricultural and Biological Sciences | 11 | 13% |
| Physics and Astronomy | 11 | 13% |
| Chemistry | 9 | 10% |
| Other | 8 | 9% |
| Unknown | 19 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2015.
All research outputs
#20,278,422
of 22,811,321 outputs
Outputs from Scientific Reports
#105,188
of 123,118 outputs
Outputs of similar age
#222,202
of 266,120 outputs
Outputs of similar age from Scientific Reports
#1,537
of 1,841 outputs
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