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Genomic-scale prioritization of drug targets: the TDR Targets database

Overview of attention for article published in Nature Reviews Drug Discovery, October 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

policy
2 policy sources
patent
2 patents
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
265 Dimensions

Readers on

mendeley
309 Mendeley
citeulike
7 CiteULike
connotea
3 Connotea
Title
Genomic-scale prioritization of drug targets: the TDR Targets database
Published in
Nature Reviews Drug Discovery, October 2008
DOI 10.1038/nrd2684
Pubmed ID
Authors

Fernán Agüero, Bissan Al-Lazikani, Martin Aslett, Matthew Berriman, Frederick S. Buckner, Robert K. Campbell, Santiago Carmona, Ian M. Carruthers, A. W. Edith Chan, Feng Chen, Gregory J. Crowther, Maria A. Doyle, Christiane Hertz-Fowler, Andrew L. Hopkins, Gregg McAllister, Solomon Nwaka, John P. Overington, Arnab Pain, Gaia V. Paolini, Ursula Pieper, Stuart A. Ralph, Aaron Riechers, David S. Roos, Andrej Sali, Dhanasekaran Shanmugam, Takashi Suzuki, Wesley C. Van Voorhis, Christophe L. M. J. Verlinde

Abstract

The increasing availability of genomic data for pathogens that cause tropical diseases has created new opportunities for drug discovery and development. However, if the potential of such data is to be fully exploited, the data must be effectively integrated and be easy to interrogate. Here, we discuss the development of the TDR Targets database (http://tdrtargets.org), which encompasses extensive genetic, biochemical and pharmacological data related to tropical disease pathogens, as well as computationally predicted druggability for potential targets and compound desirability information. By allowing the integration and weighting of this information, this database aims to facilitate the identification and prioritization of candidate drug targets for pathogens.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 309 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 7 2%
United Kingdom 6 2%
United States 5 2%
Germany 2 <1%
India 2 <1%
Turkey 1 <1%
Austria 1 <1%
Chile 1 <1%
France 1 <1%
Other 10 3%
Unknown 273 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 71 23%
Student > Ph. D. Student 56 18%
Student > Master 37 12%
Professor > Associate Professor 22 7%
Student > Doctoral Student 21 7%
Other 62 20%
Unknown 40 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 106 34%
Biochemistry, Genetics and Molecular Biology 43 14%
Medicine and Dentistry 33 11%
Chemistry 31 10%
Computer Science 11 4%
Other 32 10%
Unknown 53 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2021.
All research outputs
#2,457,465
of 22,769,322 outputs
Outputs from Nature Reviews Drug Discovery
#1,125
of 3,362 outputs
Outputs of similar age
#7,296
of 90,771 outputs
Outputs of similar age from Nature Reviews Drug Discovery
#4
of 21 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,362 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 90,771 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 21 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.