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The structure and function of G-protein-coupled receptors

Overview of attention for article published in Nature, May 2009
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

news
5 news outlets
blogs
2 blogs
twitter
2 X users
patent
25 patents
wikipedia
4 Wikipedia pages

Citations

dimensions_citation
1934 Dimensions

Readers on

mendeley
3198 Mendeley
citeulike
16 CiteULike
connotea
5 Connotea
Title
The structure and function of G-protein-coupled receptors
Published in
Nature, May 2009
DOI 10.1038/nature08144
Pubmed ID
Authors

Daniel M. Rosenbaum, Søren G. F. Rasmussen, Brian K. Kobilka

Abstract

G-protein-coupled receptors (GPCRs) mediate most of our physiological responses to hormones, neurotransmitters and environmental stimulants, and so have great potential as therapeutic targets for a broad spectrum of diseases. They are also fascinating molecules from the perspective of membrane-protein structure and biology. Great progress has been made over the past three decades in understanding diverse GPCRs, from pharmacology to functional characterization in vivo. Recent high-resolution structural studies have provided insights into the molecular mechanisms of GPCR activation and constitutive activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 3,198 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 35 1%
United Kingdom 16 <1%
Germany 13 <1%
Canada 7 <1%
Denmark 6 <1%
France 5 <1%
Netherlands 4 <1%
India 4 <1%
Brazil 3 <1%
Other 38 1%
Unknown 3067 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 631 20%
Student > Bachelor 607 19%
Student > Master 443 14%
Researcher 366 11%
Student > Doctoral Student 125 4%
Other 365 11%
Unknown 661 21%
Readers by discipline Count As %
Agricultural and Biological Sciences 789 25%
Biochemistry, Genetics and Molecular Biology 638 20%
Chemistry 312 10%
Pharmacology, Toxicology and Pharmaceutical Science 219 7%
Medicine and Dentistry 176 6%
Other 355 11%
Unknown 709 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 69. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2024.
All research outputs
#549,626
of 23,565,002 outputs
Outputs from Nature
#23,441
of 92,619 outputs
Outputs of similar age
#1,214
of 98,472 outputs
Outputs of similar age from Nature
#31
of 531 outputs
Altmetric has tracked 23,565,002 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 92,619 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 100.5. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,472 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 531 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.