| Title |
Remission of severe aphthous stomatitis of celiac disease with etanercept
|
|---|---|
| Published in |
Clinical and Molecular Allergy, December 2013
|
| DOI | 10.1186/1476-7961-11-6 |
| Pubmed ID | |
| Authors |
Adey Hasan, Hiren Patel, Hana Saleh, George Youngberg, John Litchfield, Guha Krishnaswamy |
| Abstract |
Celiac disease is a common autoimmune disease triggered by gluten-containing foods (wheat, barley and rye) in genetically predisposed individuals. We present a patient with celiac disease complicated by severe aphthous stomatitis resulting in impairing swallowing, chewing and speaking. This led to weight loss, psychosocial problems as well as inability to perform her work. A variety of topical and systemic medications used resulted in either no improvement or only partial alleviation of the patient's symptoms. After informed consent, etanercept was initiated and resulted in complete remission of aphthous stomatitis, decrease in arthralgia and fatigue and considerable improvement in her quality of life. The use of newer biological agents for selected and severe manifestations of celiac disease may lead to improved morbidity in these patients, but more studies are needed to determine long-term efficacy as well as safety of these drugs in the mucosal and/or systemic complications of this disease. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 60 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 11 | 18% |
| Researcher | 11 | 18% |
| Student > Bachelor | 8 | 13% |
| Student > Doctoral Student | 4 | 7% |
| Student > Ph. D. Student | 2 | 3% |
| Other | 3 | 5% |
| Unknown | 21 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 37% |
| Nursing and Health Professions | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 3 | 5% |
| Agricultural and Biological Sciences | 2 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
| Other | 4 | 7% |
| Unknown | 23 | 38% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2014.
All research outputs
#16,136,546
of 23,936,280 outputs
Outputs from Clinical and Molecular Allergy
#162
of 215 outputs
Outputs of similar age
#197,997
of 313,673 outputs
Outputs of similar age from Clinical and Molecular Allergy
#2
of 2 outputs
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So far Altmetric has tracked 215 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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