↓ Skip to main content

Adaptation to dietary conditions by trehalose metabolism in Drosophila

Overview of attention for article published in Scientific Reports, May 2017
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

twitter
7 tweeters
facebook
1 Facebook page

Citations

dimensions_citation
30 Dimensions

Readers on

mendeley
69 Mendeley
Title
Adaptation to dietary conditions by trehalose metabolism in Drosophila
Published in
Scientific Reports, May 2017
DOI 10.1038/s41598-017-01754-9
Pubmed ID
Authors

Tetsuo Yasugi, Takayuki Yamada, Takashi Nishimura

Abstract

Trehalose is a non-reducing disaccharide that serves as the main sugar component of haemolymph in insects. Trehalose hydrolysis enzyme, called trehalase, is highly conserved from bacteria to humans. However, our understanding of the physiological role of trehalase remains incomplete. Here, we analyze the phenotypes of several Trehalase (Treh) loss-of-function alleles in a comparative manner in Drosophila. The previously reported mutant phenotype of Treh affecting neuroepithelial stem cell maintenance and differentiation in the optic lobe is caused by second-site alleles in addition to Treh. We further report that the survival rate of Treh null mutants is significantly influenced by dietary conditions. Treh mutant larvae are lethal not only on a low-sugar diet but also under low-protein diet conditions. A reduction in adaptation ability under poor food conditions in Treh mutants is mainly caused by the overaccumulation of trehalose rather than the loss of Treh, because the additional loss of Tps1 mitigates the lethal effect of Treh mutants. These results demonstrate that proper trehalose metabolism plays a critical role in adaptation under various environmental conditions.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 69 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 32%
Researcher 11 16%
Student > Master 7 10%
Student > Bachelor 6 9%
Student > Doctoral Student 5 7%
Other 10 14%
Unknown 8 12%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 31 45%
Agricultural and Biological Sciences 23 33%
Neuroscience 2 3%
Unspecified 1 1%
Nursing and Health Professions 1 1%
Other 3 4%
Unknown 8 12%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 July 2017.
All research outputs
#3,058,910
of 11,465,445 outputs
Outputs from Scientific Reports
#16,855
of 49,545 outputs
Outputs of similar age
#86,309
of 265,743 outputs
Outputs of similar age from Scientific Reports
#1,174
of 3,202 outputs
Altmetric has tracked 11,465,445 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 49,545 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 265,743 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 3,202 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.