| Title |
The placenta as a model for understanding the origin and evolution of vertebrate organs
|
|---|---|
| Published in |
Nature Ecology & Evolution, March 2017
|
| DOI | 10.1038/s41559-017-0072 |
| Pubmed ID | |
| Authors |
Oliver W. Griffith, Günter P. Wagner |
| Abstract |
How organs originate and evolve is a question fundamental to understanding the evolution of complex multicellular life forms. Vertebrates have a relatively standard body plan with more or less the same conserved set of organs. The placenta is a comparatively more recently evolved organ, derived in many lineages independently. Using placentas as a model, we discuss the genetic basis for organ origins. We show that the evolution of placentas occurs by acquiring new functional attributes to existing tissues, changes in the patterning and development of tissues, and the evolution of novel cell types. We argue that a diversity of genomic changes facilitated these physiological transformations and that these changes are likely to have occurred during the evolution of organs more broadly. Finally, we argue that a key aspect to understanding the evolutionary origin of organs is that they are likely to result from novel interactions between distinct cell populations. |
X Demographics
The data shown below were collected from the profiles of 94 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 16 | 17% |
| United Kingdom | 7 | 7% |
| Australia | 6 | 6% |
| Brazil | 3 | 3% |
| Chile | 3 | 3% |
| Japan | 2 | 2% |
| Italy | 2 | 2% |
| Spain | 2 | 2% |
| Germany | 2 | 2% |
| Other | 12 | 13% |
| Unknown | 39 | 41% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 52 | 55% |
| Scientists | 39 | 41% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
| Practitioners (doctors, other healthcare professionals) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 125 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 25% |
| Researcher | 18 | 14% |
| Student > Master | 17 | 14% |
| Student > Bachelor | 14 | 11% |
| Professor > Associate Professor | 9 | 7% |
| Other | 16 | 13% |
| Unknown | 20 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 33% |
| Biochemistry, Genetics and Molecular Biology | 40 | 32% |
| Philosophy | 4 | 3% |
| Medicine and Dentistry | 4 | 3% |
| Immunology and Microbiology | 3 | 2% |
| Other | 10 | 8% |
| Unknown | 23 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 110. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 March 2023.
All research outputs
#388,363
of 25,918,104 outputs
Outputs from Nature Ecology & Evolution
#728
of 2,176 outputs
Outputs of similar age
#8,100
of 325,745 outputs
Outputs of similar age from Nature Ecology & Evolution
#36
of 95 outputs
Altmetric has tracked 25,918,104 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,176 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 149.7. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,745 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.