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Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche

Overview of attention for article published in Journal of Biomedical Science, September 2013
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Title
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche
Published in
Journal of Biomedical Science, September 2013
DOI 10.1186/1423-0127-20-66
Pubmed ID
Authors

Bithiah Grace Jaganathan, Fernando Anjos-Afonso, Atul Kumar, Dominique Bonnet

Abstract

Hematopoietic stem/progenitor cells (HSPCs) maintain the hematopoietic system by balancing their self-renewal and differentiation events. Hematopoietic stem cells also migrate to various sites and interact with their specific microenvironment to maintain the integrity of the system. Rho GTPases have been found to control the migration of hematopoietic cells and other cell types. Although the role of RAC1, RAC2 and CDC42 has been studied, the role of RHOA in human hematopoietic stem cells is unclear.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 25%
Researcher 7 25%
Student > Master 5 18%
Other 2 7%
Student > Bachelor 1 4%
Other 3 11%
Unknown 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 36%
Biochemistry, Genetics and Molecular Biology 5 18%
Mathematics 1 4%
Business, Management and Accounting 1 4%
Unspecified 1 4%
Other 4 14%
Unknown 6 21%