Title |
Active RHOA favors retention of human hematopoietic stem/progenitor cells in their niche
|
---|---|
Published in |
Journal of Biomedical Science, September 2013
|
DOI | 10.1186/1423-0127-20-66 |
Pubmed ID | |
Authors |
Bithiah Grace Jaganathan, Fernando Anjos-Afonso, Atul Kumar, Dominique Bonnet |
Abstract |
Hematopoietic stem/progenitor cells (HSPCs) maintain the hematopoietic system by balancing their self-renewal and differentiation events. Hematopoietic stem cells also migrate to various sites and interact with their specific microenvironment to maintain the integrity of the system. Rho GTPases have been found to control the migration of hematopoietic cells and other cell types. Although the role of RAC1, RAC2 and CDC42 has been studied, the role of RHOA in human hematopoietic stem cells is unclear. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 25% |
Researcher | 7 | 25% |
Student > Master | 5 | 18% |
Other | 2 | 7% |
Student > Bachelor | 1 | 4% |
Other | 3 | 11% |
Unknown | 3 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 10 | 36% |
Biochemistry, Genetics and Molecular Biology | 5 | 18% |
Mathematics | 1 | 4% |
Business, Management and Accounting | 1 | 4% |
Unspecified | 1 | 4% |
Other | 4 | 14% |
Unknown | 6 | 21% |