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p11 and its role in depression and therapeutic responses to antidepressants

Overview of attention for article published in Nature Reviews Neuroscience, September 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
1 news outlet
twitter
16 tweeters

Citations

dimensions_citation
114 Dimensions

Readers on

mendeley
177 Mendeley
citeulike
1 CiteULike
Title
p11 and its role in depression and therapeutic responses to antidepressants
Published in
Nature Reviews Neuroscience, September 2013
DOI 10.1038/nrn3564
Pubmed ID
Authors

Per Svenningsson, Yong Kim, Jennifer Warner-Schmidt, Yong-Seok Oh, Paul Greengard

Abstract

Studies of the multifunctional protein p11 (also known as S100A10) are shedding light on the molecular and cellular mechanisms underlying depression. Here, we review data implicating p11 in both the amplification of serotonergic signalling and the regulation of gene transcription. We summarize studies demonstrating that levels of p11 are regulated in depression and by antidepressant regimens and, conversely, that p11 regulates depression-like behaviours and/or responses to antidepressants. Current and future studies of p11 may provide a molecular and cellular framework for the development of novel antidepressant therapies.

Twitter Demographics

The data shown below were collected from the profiles of 16 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
Italy 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 170 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 39 22%
Researcher 28 16%
Student > Master 21 12%
Student > Bachelor 17 10%
Student > Doctoral Student 11 6%
Other 37 21%
Unknown 24 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 25%
Neuroscience 33 19%
Medicine and Dentistry 27 15%
Biochemistry, Genetics and Molecular Biology 23 13%
Psychology 8 5%
Other 13 7%
Unknown 29 16%

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2020.
All research outputs
#1,249,265
of 17,415,680 outputs
Outputs from Nature Reviews Neuroscience
#636
of 2,434 outputs
Outputs of similar age
#13,250
of 169,709 outputs
Outputs of similar age from Nature Reviews Neuroscience
#8
of 58 outputs
Altmetric has tracked 17,415,680 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,434 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.1. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,709 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.