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p11 and its role in depression and therapeutic responses to antidepressants

Overview of attention for article published in Nature Reviews Neuroscience, September 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

news
1 news outlet
twitter
16 X users
patent
1 patent

Citations

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144 Dimensions

Readers on

mendeley
194 Mendeley
citeulike
1 CiteULike
Title
p11 and its role in depression and therapeutic responses to antidepressants
Published in
Nature Reviews Neuroscience, September 2013
DOI 10.1038/nrn3564
Pubmed ID
Authors

Per Svenningsson, Yong Kim, Jennifer Warner-Schmidt, Yong-Seok Oh, Paul Greengard

Abstract

Studies of the multifunctional protein p11 (also known as S100A10) are shedding light on the molecular and cellular mechanisms underlying depression. Here, we review data implicating p11 in both the amplification of serotonergic signalling and the regulation of gene transcription. We summarize studies demonstrating that levels of p11 are regulated in depression and by antidepressant regimens and, conversely, that p11 regulates depression-like behaviours and/or responses to antidepressants. Current and future studies of p11 may provide a molecular and cellular framework for the development of novel antidepressant therapies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 194 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 4 2%
Italy 1 <1%
Germany 1 <1%
Canada 1 <1%
Unknown 187 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 40 21%
Researcher 35 18%
Student > Master 22 11%
Student > Bachelor 18 9%
Student > Doctoral Student 11 6%
Other 37 19%
Unknown 31 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 44 23%
Neuroscience 42 22%
Medicine and Dentistry 26 13%
Biochemistry, Genetics and Molecular Biology 23 12%
Psychology 7 4%
Other 14 7%
Unknown 38 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2022.
All research outputs
#1,581,864
of 23,577,654 outputs
Outputs from Nature Reviews Neuroscience
#707
of 2,689 outputs
Outputs of similar age
#14,368
of 198,427 outputs
Outputs of similar age from Nature Reviews Neuroscience
#9
of 57 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,689 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.6. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 198,427 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 57 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.